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Alkalizing properties of new calcium-silicate endodontic biomaterials

Katarzyna Kot, Łukasz Kucharski, Ewa Marek, Krzysztof Safranow, Mariusz Lipski

Abstract

Background: Calcium silicate-based cements (CSC), are self-setting hydraulic biomaterials widely used for reparative procedures in dentistry and endodontics. These materials possess bio-properties like biocompatibility, biointeractivity (release calcium (Ca2+ ) and hydroxyl (OH-) ions), and bioactivity (apatite-forming ability in contact with body fluids). Methods: Six calcium silicate-based materials were selected for this study: TheraCal LC (Bisco Inc. Schamburg, IL, USA), MTA Plus (Prevest Denpro, Jammu, India Avalon Biomed Inc, Bradenton, FL, USA), Biodentine (Septodont, Saint-Maur-des-Fossés, France), RetroMTA (BioMTA, Seoul, Korea), MTA Flow (Ultradent Products, Inc., South Jordan UT, USA), and OrthoMTA (BioMTA, Seoul, Korea). The pH was analysed immediately after immersion (baseline) and after 1 hour, 3 hours, 1 day, 2 days, 3 days, 1 week, 2 weeks, 3 weeks and 1 year with a pH meter, previously calibrated with solutions of known pH. To analyze the change in pH levels of the materials at each time point, 1- and 2-way analysis of variance, ANOVA followed by Tukey's multiple comparison test. The level of significance was set at p < 0.05. Results: Analysis of the tested materials showed statistically significant differences in terms of pH changes as a function of time showed a gradual rise in the pH of all materials. Conclusion: All tested materials exhibited continuous hydroxyl ion release resulting in a rise in pH until the end of time of experience. Because of the highly alkaline pH values of these materials, they possess biointeractivity properties.

Keywords
calcium silicate-based cements, biomaterials, pH, alkalizing properties

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Preprint: Please note that this article has not completed peer review.

Alkalizing properties of new calcium-silicate endodontic biomaterials

Katarzyna Kot, Łukasz Kucharski, Ewa Marek, Krzysztof Safranow, Mariusz Lipski

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Abstract

Background: Calcium silicate-based cements (CSC), are self-setting hydraulic biomaterials widely used for reparative procedures in dentistry and endodontics. These materials possess bio-properties like biocompatibility, biointeractivity (release calcium (Ca2+ ) and hydroxyl (OH-) ions), and bioactivity (apatite-forming ability in contact with body fluids). Methods: Six calcium silicate-based materials were selected for this study: TheraCal LC (Bisco Inc. Schamburg, IL, USA), MTA Plus (Prevest Denpro, Jammu, India Avalon Biomed Inc, Bradenton, FL, USA), Biodentine (Septodont, Saint-Maur-des-Fossés, France), RetroMTA (BioMTA, Seoul, Korea), MTA Flow (Ultradent Products, Inc., South Jordan UT, USA), and OrthoMTA (BioMTA, Seoul, Korea). The pH was analysed immediately after immersion (baseline) and after 1 hour, 3 hours, 1 day, 2 days, 3 days, 1 week, 2 weeks, 3 weeks and 1 year with a pH meter, previously calibrated with solutions of known pH. To analyze the change in pH levels of the materials at each time point, 1- and 2-way analysis of variance, ANOVA followed by Tukey's multiple comparison test. The level of significance was set at p < 0.05. Results: Analysis of the tested materials showed statistically significant differences in terms of pH changes as a function of time showed a gradual rise in the pH of all materials. Conclusion: All tested materials exhibited continuous hydroxyl ion release resulting in a rise in pH until the end of time of experience. Because of the highly alkaline pH values of these materials, they possess biointeractivity properties.

Figures

Background

Methods

Results

Discussion

Conclusion

Abbreviations

Declarations

References

Tables

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