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Method Article
Crystallization of Cryptophane-A and Cryptophane-A Derivatives with and without Encapsulated Guests
Ivan J. Dmochowski
Department of Chemistry, University of Pennsylvania, 231 South 34th St., Philadelphia, PA 19104
Corresponding Author
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Detailed protocols for crystallizing cryptophane-guest complexes are provided. Cryptophane molecular cages (cryptophane-A, also tripropargyl and triallyl derivatives) were crystallized with water, xenon, methanol, or without guest via the vapor diffusion method and with chloroform via slow evaporation. The average time required to grow cryptophane crystals is 1 week.
Keywords
xenon, cryptophane, host-guest chemistry, small molecule X-ray crystallography, organic chemistry, analytical chemistry
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Protocol Crystallization of Cryptophane-A and Cryptophane-A Derivatives
commented on 05 June, 2011
Hello,I was wondering if you have a refined crystal structure for these compounds.Thanks!
commented on 06 June, 2011
Todd, we deposited the coordinates to several cryptophane structures in conjunction with our 2010 Nature Communications paper: O. Taratula, P.A. Hill, N.S. Khan, P.J. Carroll, I.J. Dmochowski, Crystallographic observation of â–induced fit' in a cryptophane host-guest model system, Nature Commun., 1:148, doi:10.1038/ncomms1151, 2010.If you just want to see the structures, you can refer to that paper. Best wishes,Ivan
commented on 05 June, 2011
Hello,I was wondering if you have a refined crystal structure for these compounds.Thanks!
commented on 06 June, 2011
Todd, we deposited the coordinates to several cryptophane structures in conjunction with our 2010 Nature Communications paper: O. Taratula, P.A. Hill, N.S. Khan, P.J. Carroll, I.J. Dmochowski, Crystallographic observation of â–induced fit' in a cryptophane host-guest model system, Nature Commun., 1:148, doi:10.1038/ncomms1151, 2010.If you just want to see the structures, you can refer to that paper. Best wishes,Ivan
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Associated Publications
Crystallographic observation of 'induced fit' in a cryptophane host–guest model system
by Olena Taratula, P. Aru Hill, Najat S. Khan, +2
Nature Communications (02 February, 2011)
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This is a preprint. It has not completed peer review.
Method Article
Crystallization of Cryptophane-A and Cryptophane-A Derivatives with and without Encapsulated Guests
Ivan J. Dmochowski
Department of Chemistry, University of Pennsylvania, 231 South 34th St., Philadelphia, PA 19104
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 04 Feb, 2011
Community comments: 4
Metrics
Comments: 4
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY-NC 3.0 License. Read Full License
Detailed protocols for crystallizing cryptophane-guest complexes are provided. Cryptophane molecular cages (cryptophane-A, also tripropargyl and triallyl derivatives) were crystallized with water, xenon, methanol, or without guest via the vapor diffusion method and with chloroform via slow evaporation. The average time required to grow cryptophane crystals is 1 week.
Figure 1
Figure 2
commented on 05 June, 2011
Hello,I was wondering if you have a refined crystal structure for these compounds.Thanks!
commented on 06 June, 2011
Todd, we deposited the coordinates to several cryptophane structures in conjunction with our 2010 Nature Communications paper: O. Taratula, P.A. Hill, N.S. Khan, P.J. Carroll, I.J. Dmochowski, Crystallographic observation of â–induced fit' in a cryptophane host-guest model system, Nature Commun., 1:148, doi:10.1038/ncomms1151, 2010.If you just want to see the structures, you can refer to that paper. Best wishes,Ivan
commented on 05 June, 2011
Hello,I was wondering if you have a refined crystal structure for these compounds.Thanks!
commented on 06 June, 2011
Todd, we deposited the coordinates to several cryptophane structures in conjunction with our 2010 Nature Communications paper: O. Taratula, P.A. Hill, N.S. Khan, P.J. Carroll, I.J. Dmochowski, Crystallographic observation of â–induced fit' in a cryptophane host-guest model system, Nature Commun., 1:148, doi:10.1038/ncomms1151, 2010.If you just want to see the structures, you can refer to that paper. Best wishes,Ivan
Associated Publications
Crystallographic observation of 'induced fit' in a cryptophane host–guest model system
by Olena Taratula, P. Aru Hill, Najat S. Khan, +2
Nature Communications (02 February, 2011)