Synthesis of terpyridine-modified peptides
The synthesis of peptides with a terpyridine chelating ligand attached to a lysine side chain is described. The main advantage of this methodology relies on the introduction of the terpyridine unit while the peptide is still in the solid phase, thus avoiding reactions in solution and laborious HPLC purifications of synthetic intermediates.
Figure 1
Posted 22 May, 2013
Synthesis of terpyridine-modified peptides
Posted 22 May, 2013
The synthesis of peptides with a terpyridine chelating ligand attached to a lysine side chain is described. The main advantage of this methodology relies on the introduction of the terpyridine unit while the peptide is still in the solid phase, thus avoiding reactions in solution and laborious HPLC purifications of synthetic intermediates.
Figure 1