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Method Article
M. Ryan Corces
Howard Chang Lab
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
We present Omni-ATAC, an improved ATAC-seq protocol for chromatin accessibility profiling that works universally across multiple cell types and cell contexts with significant improvement of signal-to-background ratio and information content. The Omni-ATAC protocol enables chromatin accessibility profiling from material that was previously deemed intractable including frozen tissue samples.
Keywords
ATAC-seq
Figure 1
Howard Y. Chang and William J. Greenleaf are co-founders and consultants of Epinomics. Anshul Kundaje is a member of the scientific advisory board of Epinomics.
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Posted 29 Aug, 2017
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Genetics
Associated Publications
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
by M Ryan Corces, Alexandro E Trevino, Emily G Hamilton, +12
Nature Methods (29 August, 2017)
An open repository of community-contributed protocols sponsored by Nature Research.
Learn more about Protocol Exchange
Method Article
M. Ryan Corces
Howard Chang Lab
Corresponding Author
Version History
CURRENT STATUS: Posted
Version 1
Posted 29 Aug, 2017
Community comments: 1
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Genetics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
We present Omni-ATAC, an improved ATAC-seq protocol for chromatin accessibility profiling that works universally across multiple cell types and cell contexts with significant improvement of signal-to-background ratio and information content. The Omni-ATAC protocol enables chromatin accessibility profiling from material that was previously deemed intractable including frozen tissue samples.
Figure 1
Howard Y. Chang and William J. Greenleaf are co-founders and consultants of Epinomics. Anshul Kundaje is a member of the scientific advisory board of Epinomics.
Loading...
Associated Publications
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
by M Ryan Corces, Alexandro E Trevino, Emily G Hamilton, +12
Nature Methods (29 August, 2017)