This preprint is under consideration at The International Journal of Cardiovascular Imaging. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
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Research Article
Amiliana Mardiani Soesanto
Dept. Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/ National Cardiovascular Center, Harapan Kita
Corresponding Author
ORCiD: https://orcid.org/0000-0001-7898-4570
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This work is licensed under a CC BY 4.0 License. Read Full License
Background: Several studies have reported left ventricular systolic dysfunction as measured by the global longitudinal strain (GLS) in patients with mitral stenosis. This study aims to determine left ventricular systolic function changes using global longitudinal strain early after balloon mitral valvuloplasty (BMV) and on long-term observation.
Methods: Baseline echocardiography data and GLS were taken before BMV, followed up early after (2 to 7 days), and in the long-term (6 months to 1 year) after BMV.
Result: Among 36 patients, the mean age was 43.41±10.04 y.o, female dominant (72%); the majority have atrial fibrillation (56%), with a median mitral valve area (MVA) before BMV of 0.6 (0.2-1.3) cm2 and mean mitral valve gradient before BMV of 12.95 ± 5.29 mmHg. GLS increased from -14.34 ± 3.05% to 15.84 ±3.11% and increased further to -17.29 ± 2.80% (p<0.05), at pre-BMV- early post-BMV, and long-term follow up, respectively.
Conclusions: There is a significant improvement in LV GLS early after BMV compare to baseline. The GLS improved further at long-term evaluation (six months until one year) after BMV.
Keywords
GLS, stenosis mitral, BMV, left ventricular, valvuloplasty
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CURRENT STATUS: Under Review
Version 1
Posted 29 Oct, 2021
No community comments so far
Editor invited
On 05 Dec, 2021
Reviews received
Received 07 Nov, 2021
Reviewers invited
Invitations sent on 27 Oct, 2021
Editor assigned
On 26 Oct, 2021
First submitted
On 25 Oct, 2021
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This preprint is under consideration at The International Journal of Cardiovascular Imaging. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Amiliana Mardiani Soesanto
Dept. Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/ National Cardiovascular Center, Harapan Kita
Corresponding Author
ORCiD: https://orcid.org/0000-0001-7898-4570
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 29 Oct, 2021
No community comments so far
Editor invited
On 05 Dec, 2021
Reviews received
Received 07 Nov, 2021
Reviewers invited
Invitations sent on 27 Oct, 2021
Editor assigned
On 26 Oct, 2021
First submitted
On 25 Oct, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Several studies have reported left ventricular systolic dysfunction as measured by the global longitudinal strain (GLS) in patients with mitral stenosis. This study aims to determine left ventricular systolic function changes using global longitudinal strain early after balloon mitral valvuloplasty (BMV) and on long-term observation.
Methods: Baseline echocardiography data and GLS were taken before BMV, followed up early after (2 to 7 days), and in the long-term (6 months to 1 year) after BMV.
Result: Among 36 patients, the mean age was 43.41±10.04 y.o, female dominant (72%); the majority have atrial fibrillation (56%), with a median mitral valve area (MVA) before BMV of 0.6 (0.2-1.3) cm2 and mean mitral valve gradient before BMV of 12.95 ± 5.29 mmHg. GLS increased from -14.34 ± 3.05% to 15.84 ±3.11% and increased further to -17.29 ± 2.80% (p<0.05), at pre-BMV- early post-BMV, and long-term follow up, respectively.
Conclusions: There is a significant improvement in LV GLS early after BMV compare to baseline. The GLS improved further at long-term evaluation (six months until one year) after BMV.
Figure 1
This is a list of supplementary files associated with this preprint. Click to download.
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