This preprint is under consideration at BMC Pediatrics. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
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Research Article
Qi Yan
School of public health, Xinjiang Medical University
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
Allergic rhinitis is a disease associated with impaired quality of life and heredity. This study aimed to investigate the association of allergic rhinitis (AR) in preschool children with exposure to indoor environment-related factors early in life.
Methods
In August 2019, we implemented a study among 2020 preschool children in Urumqi City using a case-control design. The study included parental reports for the occurrence of AR in children, parental history of respiratory disease, and indoor environmental correlates of maternal exposure from 1 year prior to pregnancy until the child's age of 0-1 years.
Results
Mode of birth (caesarean section) (OR=1.31, 95%CI=1.02~1.67), father with AR (OR=2.67, 95%CI=2.08~3.44), mother with AR (OR=3.70, 95%CI=2.88~4.74), mother with asthma (OR=3.11, 95%CI=1.18~8.20), and mother with newly purchased furniture in the parents' residence during pregnancy (OR=1.49, 95%CI=1.03~2.14) were risk factors for AR in children.
Conclusions
The focus of allergic rhinitis should should be on children with a family history of AR and asthma and caesarean delivery. Primary prevention efforts for AR in preschool children are avoiding exposure of children to indoor environmental hazardous factors early in life.
Keywords
Parental, Gestational, Early-life Exposure, Preschool Children
No competing interests reported.
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Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 08 Nov, 2021
No community comments so far
Reviewers agreed
On 29 Nov, 2021
Reviewers invited
Invitations sent on 28 Oct, 2021
Editor assigned
On 28 Oct, 2021
Editor invited
On 27 Oct, 2021
Submission checks complete
On 27 Oct, 2021
First submitted
On 26 Oct, 2021
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Subject Areas
Pediatrics
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This preprint is under consideration at BMC Pediatrics. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Qi Yan
School of public health, Xinjiang Medical University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 08 Nov, 2021
No community comments so far
Reviewers agreed
On 29 Nov, 2021
Reviewers invited
Invitations sent on 28 Oct, 2021
Editor assigned
On 28 Oct, 2021
Editor invited
On 27 Oct, 2021
Submission checks complete
On 27 Oct, 2021
First submitted
On 26 Oct, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Pediatrics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
Allergic rhinitis is a disease associated with impaired quality of life and heredity. This study aimed to investigate the association of allergic rhinitis (AR) in preschool children with exposure to indoor environment-related factors early in life.
Methods
In August 2019, we implemented a study among 2020 preschool children in Urumqi City using a case-control design. The study included parental reports for the occurrence of AR in children, parental history of respiratory disease, and indoor environmental correlates of maternal exposure from 1 year prior to pregnancy until the child's age of 0-1 years.
Results
Mode of birth (caesarean section) (OR=1.31, 95%CI=1.02~1.67), father with AR (OR=2.67, 95%CI=2.08~3.44), mother with AR (OR=3.70, 95%CI=2.88~4.74), mother with asthma (OR=3.11, 95%CI=1.18~8.20), and mother with newly purchased furniture in the parents' residence during pregnancy (OR=1.49, 95%CI=1.03~2.14) were risk factors for AR in children.
Conclusions
The focus of allergic rhinitis should should be on children with a family history of AR and asthma and caesarean delivery. Primary prevention efforts for AR in preschool children are avoiding exposure of children to indoor environmental hazardous factors early in life.
No competing interests reported.
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