This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Sara Hajishizari
Tehran University of Medical Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0001-9856-811X
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Objective: Low resting metabolic rate (RMR) as a risk factor for weight gain and obesity can be influenced by many factors. Researchers have pointed out the role of appetite and related hormones in obesity and energy intake. The aim of this study was to investigate the relationship between appetite and related hormones in the two groups with normal and impaired resting metabolic rate in overweight or obese Iranian women.
Methods: In this case-control study, 42 healthy female volunteers aged 18-50 years (21 cases,and 21 controls) participated and were evaluated for RMR by indirect calorimetry. Body composition was determined by a body composition analyzer. The Filint questionnaire was used to assess appetite. We also used ELISA kits to assess appetite-related hormones. Finally, the data were analyzed using SPSS software version 25.
Results: The results of the study showed that there is a negative relationship between ghrelin hormone level (p-value = 0.024) and RMR, and there is a positive relationship between insulin hormone level (p-value = 0.001) and RMR. Also, result of the appetite questionnaire showed that in general, both appetite (p-value = 0.044) and hunger index (p-value = 0.043) have a positive relationship with RMR. There was no significant relationship between leptin levels and RMR.
Conclusion: As the results of this study show, it seems that appetite and related hormones have a possible role in promoting RMR.
Keywords
Energy expenditure, Obesity, Resting metabolic rate, Appetite, Ghrelin, Leptin, Insulin
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Sara Hajishizari
Tehran University of Medical Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0001-9856-811X
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 01 Nov, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Nutrition & Dietetics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Objective: Low resting metabolic rate (RMR) as a risk factor for weight gain and obesity can be influenced by many factors. Researchers have pointed out the role of appetite and related hormones in obesity and energy intake. The aim of this study was to investigate the relationship between appetite and related hormones in the two groups with normal and impaired resting metabolic rate in overweight or obese Iranian women.
Methods: In this case-control study, 42 healthy female volunteers aged 18-50 years (21 cases,and 21 controls) participated and were evaluated for RMR by indirect calorimetry. Body composition was determined by a body composition analyzer. The Filint questionnaire was used to assess appetite. We also used ELISA kits to assess appetite-related hormones. Finally, the data were analyzed using SPSS software version 25.
Results: The results of the study showed that there is a negative relationship between ghrelin hormone level (p-value = 0.024) and RMR, and there is a positive relationship between insulin hormone level (p-value = 0.001) and RMR. Also, result of the appetite questionnaire showed that in general, both appetite (p-value = 0.044) and hunger index (p-value = 0.043) have a positive relationship with RMR. There was no significant relationship between leptin levels and RMR.
Conclusion: As the results of this study show, it seems that appetite and related hormones have a possible role in promoting RMR.
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