This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research article
Outcomes of a retrospective study on sustained release betamethasone for transient radicular symptoms in patients after Transforaminal Lumbar Interbody Fusion operation
Weihu Ma
Ningbo No 6 Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0003-3568-6201
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Objective To observe the efficacy and Complications of gelatin sponge sustained release betamethasone for transient radicular symptoms in patients after TLIF operation.
Method A total of 218 patients with single-level LDH were retrospectively analyzed from March 2017 to July 2019. Patients were divided into observation group and control groups according to different approach.Clinical data such as lasegue sign, VAS score, ODI index were compared, the data analyzed by SPSS 24.0 statistical software.
Results 186 patients were finally included. The observation group has significantly different between the control groups(P<0.05)at five days after surgery. And there was no significant difference in VAS and ODI between the four groups (P > 0.05)at 2-3 months after surgery, . There was no significant difference in blood glucose before and after operation in the observation group(P > 0.05), and numeration of leukocyte in the four groups was significantly higher than before operation (P<0.05), but there was no statistically significant difference between the four groups before and after operation (P > 0.05). The patients in the four groups had basically the same satisfaction with the final efficacy (> 90%) . In addition, there was the same Complications in four groups(eg.postoperative nausea, vomiting and other complications.)
Conclusion the use of gelatin sponge sustained-release steroids and other mixed solutions can significantly relieve transient radicular symptoms after TLIF operation,and does not influence the occurrence of postoperative complications.
Keywords
TLIF, Lumbar disc herniation, radicular symptoms, steroid
Figure 1
Figure 2
Figure 3
Figure 4
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 30 Dec, 2019
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedic Surgery
Learn more about our company.
This is a preprint. It has not completed peer review.
Research article
Outcomes of a retrospective study on sustained release betamethasone for transient radicular symptoms in patients after Transforaminal Lumbar Interbody Fusion operation
Weihu Ma
Ningbo No 6 Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0003-3568-6201
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 30 Dec, 2019
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedic Surgery
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Objective To observe the efficacy and Complications of gelatin sponge sustained release betamethasone for transient radicular symptoms in patients after TLIF operation.
Method A total of 218 patients with single-level LDH were retrospectively analyzed from March 2017 to July 2019. Patients were divided into observation group and control groups according to different approach.Clinical data such as lasegue sign, VAS score, ODI index were compared, the data analyzed by SPSS 24.0 statistical software.
Results 186 patients were finally included. The observation group has significantly different between the control groups(P<0.05)at five days after surgery. And there was no significant difference in VAS and ODI between the four groups (P > 0.05)at 2-3 months after surgery, . There was no significant difference in blood glucose before and after operation in the observation group(P > 0.05), and numeration of leukocyte in the four groups was significantly higher than before operation (P<0.05), but there was no statistically significant difference between the four groups before and after operation (P > 0.05). The patients in the four groups had basically the same satisfaction with the final efficacy (> 90%) . In addition, there was the same Complications in four groups(eg.postoperative nausea, vomiting and other complications.)
Conclusion the use of gelatin sponge sustained-release steroids and other mixed solutions can significantly relieve transient radicular symptoms after TLIF operation,and does not influence the occurrence of postoperative complications.
Figure 1
Figure 2
Figure 3
Figure 4