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Research Article
Mei-Hua Hu
Chang Gung University
Corresponding Author
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Surgery is required for the treatment of intussusception when enema reduction is unsuccessful, or when the patient develops peritonitis, bowel perforation, or intestinal damage. We aimed to evaluate the clinical and laboratory parameters that may be used to predict the need for bowel resection in children with intussusception. This observational retrospective study included children who were admitted to the pediatric emergency room with intussusception. Multivariate logistic regression models were used to evaluate factors associated with bowel resection. In total, 584 children with intussusception were admitted to the pediatric emergency room; 129 of these children underwent surgery. Multivariate analysis revealed the following independent predictors of surgery for intussusception: abdominal pain (odds ratio [OR] = 0.372; p = 0.013), bloody stool (OR = 3.553; p = 0.044), and hyponatremia (OR = 4.12; 95% p = 0.003). Symptoms for at least 2 days before surgery (OR = 6.863; p = 0.009), long intussusception (OR = 5.088; p = 0.014), pathological lead point (OR = 6.926; p = 0.003), and intensive care unit admission (OR = 11.777; p = 0.001) were factors independently associated with bowel resection. These findings can be used to identify patients at high risk of needing surgery and bowel resection.
Keywords
intussusception, resection, hyponatremia, gangrene, operation
No competing interests reported.
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This preprint is under consideration at Scientific Reports. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Mei-Hua Hu
Chang Gung University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 16 Nov, 2021
No community comments so far
Editor invited
On 14 Nov, 2021
Submission checks complete
On 14 Nov, 2021
First submitted
On 02 Nov, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Surgery is required for the treatment of intussusception when enema reduction is unsuccessful, or when the patient develops peritonitis, bowel perforation, or intestinal damage. We aimed to evaluate the clinical and laboratory parameters that may be used to predict the need for bowel resection in children with intussusception. This observational retrospective study included children who were admitted to the pediatric emergency room with intussusception. Multivariate logistic regression models were used to evaluate factors associated with bowel resection. In total, 584 children with intussusception were admitted to the pediatric emergency room; 129 of these children underwent surgery. Multivariate analysis revealed the following independent predictors of surgery for intussusception: abdominal pain (odds ratio [OR] = 0.372; p = 0.013), bloody stool (OR = 3.553; p = 0.044), and hyponatremia (OR = 4.12; 95% p = 0.003). Symptoms for at least 2 days before surgery (OR = 6.863; p = 0.009), long intussusception (OR = 5.088; p = 0.014), pathological lead point (OR = 6.926; p = 0.003), and intensive care unit admission (OR = 11.777; p = 0.001) were factors independently associated with bowel resection. These findings can be used to identify patients at high risk of needing surgery and bowel resection.
No competing interests reported.
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