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Protocol
Patrícia Rezende do Prado
University of São Paulo at Ribeirão Preto College of Nursing
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3563-6602
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Critically ill patients are vulnerable to corneal injury and the incidence of this adverse event remains high in these patients. Randomized clinical trials have been assessing different types of interventions, hindering nurses' clinical practice for the prevention of corneal injury in critically ill patients. The aim of this systematic review is to identify the most effective nursing interventions to prevent corneal injury in critically ill sedated and mechanically ventilated patients.
Methods: A systematic review of intervention studies will be conducted and reported according to the Preferred Reporting Items for Systematic Reviews and Meta Analyses 2020, in the following electronic databases: Cumulative Index to Nursing and Allied Health Literature, Cochrane Central, Embase, Latin American and Caribbean Literature in Health Sciences, Livivo, PubMed, Scopus and Web of Science. The search of the grey literature will be undertaken on Google Scholar. No language or year of publication restrictions will be applied for the selection of primary studies. Study selection and data extraction will be performed by two independent reviewers who will screen the titles and abstracts of the retrieved papers to assess the studies for inclusion. Disagreements between reviewers, during study selection, will be resolved by discussion with a third reviewer. The inclusion criteria will be epidemiologic intervention studies evaluating nursing interventions to prevent or decrease the occurrence of corneal injury in critically ill sedated and mechanically ventilated patients. Methodological quality of the studies will be assessed using the Risk of Bias and Robins-2 tools. Quality of evidence will be assessed using the Grading of Recommendations Assessment, Development and Evaluation system.
Discussion: this study has a potencial to identify the most effective nursing interventions for prevention corneal injury in critically ill sedated and mechanically ventilated patients.
Systematic review registration: The protocol of this research is approved in PROSPERO under protocol No. 253289.
Keywords
Nursing, Intensive care units, Corneal injuries, Disease prevention, Evidence-based nursing, Systematic review protocol.
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CURRENT STATUS: Under Review
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Posted 15 Nov, 2021
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On 11 Nov, 2021
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This preprint is under consideration at Systematic Reviews. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Protocol
Patrícia Rezende do Prado
University of São Paulo at Ribeirão Preto College of Nursing
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3563-6602
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 15 Nov, 2021
Community comments: 1
Submission checks complete
On 11 Nov, 2021
First submitted
On 04 Nov, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Internal Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Critically ill patients are vulnerable to corneal injury and the incidence of this adverse event remains high in these patients. Randomized clinical trials have been assessing different types of interventions, hindering nurses' clinical practice for the prevention of corneal injury in critically ill patients. The aim of this systematic review is to identify the most effective nursing interventions to prevent corneal injury in critically ill sedated and mechanically ventilated patients.
Methods: A systematic review of intervention studies will be conducted and reported according to the Preferred Reporting Items for Systematic Reviews and Meta Analyses 2020, in the following electronic databases: Cumulative Index to Nursing and Allied Health Literature, Cochrane Central, Embase, Latin American and Caribbean Literature in Health Sciences, Livivo, PubMed, Scopus and Web of Science. The search of the grey literature will be undertaken on Google Scholar. No language or year of publication restrictions will be applied for the selection of primary studies. Study selection and data extraction will be performed by two independent reviewers who will screen the titles and abstracts of the retrieved papers to assess the studies for inclusion. Disagreements between reviewers, during study selection, will be resolved by discussion with a third reviewer. The inclusion criteria will be epidemiologic intervention studies evaluating nursing interventions to prevent or decrease the occurrence of corneal injury in critically ill sedated and mechanically ventilated patients. Methodological quality of the studies will be assessed using the Risk of Bias and Robins-2 tools. Quality of evidence will be assessed using the Grading of Recommendations Assessment, Development and Evaluation system.
Discussion: this study has a potencial to identify the most effective nursing interventions for prevention corneal injury in critically ill sedated and mechanically ventilated patients.
Systematic review registration: The protocol of this research is approved in PROSPERO under protocol No. 253289.
This is a list of supplementary files associated with this preprint. Click to download.
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