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Research article
Elnaz Faramarzi
liver and Gastrointestinal Diseases Research center, Tabriz university of Medical Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0003-4128-433X
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background : The aim of present study was to evaluate the association between diabetic retinopathy (DR), dietary inflammatory index (DII), and metabolic syndrome (MetS) in patients with type 2 diabetes in a cohort study in Iran.
Methods: This cross-sectional study was a part of the large Azar eye cohort study that included 1378 patients with type 2 diabetes. To diagnose DR, two mydriatric fundus photographs were captured using a digital fundus camera. The DR severity was classified as non-proliferative diabetic retinopathy (NPDR) or proliferative diabetic retinopathy (PDR). MetS was determined on the basis of the ATPIII criteria. DII was calculated according to Shivappa et al. method.
Results: Of 1378 diabetic patients, 185 (13.4%) had NPDR and 142 (10.3%) had PDR. The risk of NPDR and PDR increased by 2.65-fold and 2.01-fold, respectively, in patients having blood glucose levels that fell outside the recommended range. There was no statistically significant relationship between Mets, Mets components, and DII in NPDR and PDR.
Conclusion: The results suggest that intensive glycemic control, rather than conventional control, may help reduce the progression of DR. It seems that longitudinal studies and clinical trials for evaluating role of DII in DR are necessary.
Keywords
Type 2 diabetes, diabetic retinopathy, non-proliferative diabetic retinopathy, proliferative diabetic retinopathy, metabolic syndrome
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Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 18 Nov, 2020
No community comments so far
Review #1 received
Received 25 Jul, 2021
Reviewer #2 agreed
On 27 Jun, 2021
Reviews received
Received 27 Jun, 2021
Reviewer #1 agreed
On 09 Apr, 2021
Reviewers invited
Invitations sent on 22 Mar, 2021
Editor assigned
On 09 Nov, 2020
Submission checks complete
On 09 Nov, 2020
Editor invited
On 09 Nov, 2020
First submitted
On 07 Nov, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Nutrition & Dietetics
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A new preprint design is coming!
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This preprint is under consideration at Journal of Health, Population and Nutrition. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Elnaz Faramarzi
liver and Gastrointestinal Diseases Research center, Tabriz university of Medical Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0003-4128-433X
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 18 Nov, 2020
No community comments so far
Review #1 received
Received 25 Jul, 2021
Reviewer #2 agreed
On 27 Jun, 2021
Reviews received
Received 27 Jun, 2021
Reviewer #1 agreed
On 09 Apr, 2021
Reviewers invited
Invitations sent on 22 Mar, 2021
Editor assigned
On 09 Nov, 2020
Submission checks complete
On 09 Nov, 2020
Editor invited
On 09 Nov, 2020
First submitted
On 07 Nov, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Nutrition & Dietetics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background : The aim of present study was to evaluate the association between diabetic retinopathy (DR), dietary inflammatory index (DII), and metabolic syndrome (MetS) in patients with type 2 diabetes in a cohort study in Iran.
Methods: This cross-sectional study was a part of the large Azar eye cohort study that included 1378 patients with type 2 diabetes. To diagnose DR, two mydriatric fundus photographs were captured using a digital fundus camera. The DR severity was classified as non-proliferative diabetic retinopathy (NPDR) or proliferative diabetic retinopathy (PDR). MetS was determined on the basis of the ATPIII criteria. DII was calculated according to Shivappa et al. method.
Results: Of 1378 diabetic patients, 185 (13.4%) had NPDR and 142 (10.3%) had PDR. The risk of NPDR and PDR increased by 2.65-fold and 2.01-fold, respectively, in patients having blood glucose levels that fell outside the recommended range. There was no statistically significant relationship between Mets, Mets components, and DII in NPDR and PDR.
Conclusion: The results suggest that intensive glycemic control, rather than conventional control, may help reduce the progression of DR. It seems that longitudinal studies and clinical trials for evaluating role of DII in DR are necessary.
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