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Study protocol
Postoperative analgesic effect of acupotomy combined with patient-controlled intravenous analgesia in patients undergoing video-assisted thoracoscopic surgery: A study protocol for a randomized controlled trial
zhonghua lin
Fujian Provincial Hospital
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published version at Trials.
Background: Postoperative acute pain is a common issue following thoracic surgery. Acupotomy is a common and safe intervention method for pain treatment in the clinic. In previous preliminary experiments, we found that acupotomy has a good clinical effect and safety in the treatment of pain after thoracoscopic surgery. However, due to a lack of rigorous design and adequate sample size, the efficacy still needs to be further confirmed. The purpose of this study will be to explore the efficacy and safety of acupotomy combined with patient-controlled intravenous analgesia (PCIA) for the treatment of pain after video-assisted thoracic surgery (VATS).
Methods: The study will be a single-centre, parallel group, randomized controlled trial. Seventy patients with significant pain after thoracoscopic surgery with a visual analogue scale (VAS) score ≥7 will be included and randomly distributed into two groups: G1, the acupotomy combined with PCIA group; or G2, the conventional PCIA group. The primary outcome measure is pain scores at rest and coughing evaluated with the VAS by a blinded observer in the PACU and postoperatively at 1, 2, 4, 8, 12, 24, 48 and 72 h. The secondary outcome measures are postoperative requirements for rescue analgesia, the cumulative amount of self-administered analgesics, the level of sedation (LOS), Bruggemann comfort scale (BCS), and functional activity score (FAS) concerning adverse effects and patient satisfaction.
Discussion: This trial has the potential to identify a novel strategy for postoperative pain management in VATS. Findings may advocate for the inclusion of the treatment of comorbid pain after thoracoscopy in current pain management practice guidelines.
Keywords
acupotomy, patient-controlled intravenous analgesia, video-assisted thoracoscopic surgery, protocol
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CURRENT STATUS: Published
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Posted 07 Jan, 2020
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On 04 Dec, 2020
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Editorial decision: Major revision
On 19 May, 2020
Review #6 received
Received 11 May, 2020
Review #3 received
Received 01 May, 2020
Review #2 received
Received 01 May, 2020
Reviewer #7 agreed
On 01 May, 2020
Review #7 received
Received 01 May, 2020
Review #5 received
Received 28 Apr, 2020
Reviewer #4 agreed
On 27 Apr, 2020
Reviewer #5 agreed
On 27 Apr, 2020
Review #4 received
Received 27 Apr, 2020
Reviewer #6 agreed
On 27 Apr, 2020
Reviewer #3 agreed
On 26 Apr, 2020
Reviewers invited
Invitations sent on 25 Apr, 2020
Reviewer #1 agreed
On 25 Apr, 2020
Reviewer #2 agreed
On 25 Apr, 2020
Review #1 received
Received 25 Apr, 2020
Editor assigned
On 21 Jan, 2020
Submission checks complete
On 04 Jan, 2020
First submitted
On 19 Dec, 2019
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This preprint is under consideration at Trials. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Study protocol
Postoperative analgesic effect of acupotomy combined with patient-controlled intravenous analgesia in patients undergoing video-assisted thoracoscopic surgery: A study protocol for a randomized controlled trial
zhonghua lin
Fujian Provincial Hospital
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
Version 1
Posted 07 Jan, 2020
Published
On 04 Dec, 2020
No community comments so far
Editorial decision: Major revision
On 19 May, 2020
Review #6 received
Received 11 May, 2020
Review #3 received
Received 01 May, 2020
Review #2 received
Received 01 May, 2020
Reviewer #7 agreed
On 01 May, 2020
Review #7 received
Received 01 May, 2020
Review #5 received
Received 28 Apr, 2020
Reviewer #4 agreed
On 27 Apr, 2020
Reviewer #5 agreed
On 27 Apr, 2020
Review #4 received
Received 27 Apr, 2020
Reviewer #6 agreed
On 27 Apr, 2020
Reviewer #3 agreed
On 26 Apr, 2020
Reviewers invited
Invitations sent on 25 Apr, 2020
Reviewer #1 agreed
On 25 Apr, 2020
Reviewer #2 agreed
On 25 Apr, 2020
Review #1 received
Received 25 Apr, 2020
Editor assigned
On 21 Jan, 2020
Submission checks complete
On 04 Jan, 2020
First submitted
On 19 Dec, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published version at Trials.
Background: Postoperative acute pain is a common issue following thoracic surgery. Acupotomy is a common and safe intervention method for pain treatment in the clinic. In previous preliminary experiments, we found that acupotomy has a good clinical effect and safety in the treatment of pain after thoracoscopic surgery. However, due to a lack of rigorous design and adequate sample size, the efficacy still needs to be further confirmed. The purpose of this study will be to explore the efficacy and safety of acupotomy combined with patient-controlled intravenous analgesia (PCIA) for the treatment of pain after video-assisted thoracic surgery (VATS).
Methods: The study will be a single-centre, parallel group, randomized controlled trial. Seventy patients with significant pain after thoracoscopic surgery with a visual analogue scale (VAS) score ≥7 will be included and randomly distributed into two groups: G1, the acupotomy combined with PCIA group; or G2, the conventional PCIA group. The primary outcome measure is pain scores at rest and coughing evaluated with the VAS by a blinded observer in the PACU and postoperatively at 1, 2, 4, 8, 12, 24, 48 and 72 h. The secondary outcome measures are postoperative requirements for rescue analgesia, the cumulative amount of self-administered analgesics, the level of sedation (LOS), Bruggemann comfort scale (BCS), and functional activity score (FAS) concerning adverse effects and patient satisfaction.
Discussion: This trial has the potential to identify a novel strategy for postoperative pain management in VATS. Findings may advocate for the inclusion of the treatment of comorbid pain after thoracoscopy in current pain management practice guidelines.
Figure 1