Important reason for considering these published articles is that, they relate to renal failure reasons, role and applications of radionuclide studies, radiotracers classification by their intake and excretion mechanisms as agents for glomerular filtration, tubular secretion or cortical binding.
Also, they assess parenchymal radiotracer’s uptake and excretion process, computer created time activity graphs with dynamic visual presentation of change in activity over the whole process. Similarly, they assess various mathematical image and signal processing techniques including its quantitative or statistical analysis.
3.1 Distribution and Analysis of Article’s keywords
a. Keywords related to Image Processing
For the search of articles related to renogram processing 43 keywords were selected that were purely related to image processing technics and methods.
From main 43 keywords 7 words (16%) were linked to Rutland-Patlak method, 7 words (16%) were related to statistical methods, 6 words (14%) were associated to Deconvolution techniques,5 words (12%) related to various image types, 4 words (9%) were related to matrix methods and region of interest. 6 words (14%) were correlated to background subtraction techniques and filtration methods, and 8 words (19%) foX4und to be correlated with images noise and segmentation techniques.
b. Keywords related to Renogram parameters
Total 32 words are selected to search articles of renogram processing out of which 10 words (31%) are related to renal function,8 words are related (25%) are related to transit time, 6 words (19%) wee associated to glomerular filtration rate, 8 words (25%) were related to split function and retention function.
c. Keywords related to Radiotracers
Keywords related to radiotracers are distributed in 6 parameters. Out of 38 keywords, 9 words (24%) were related to MAG3, 8words (21%) were related to DTPA,7+7 words (37%) are associated with Technetium radionuclide and 5 words (13%) of renogram isotope while only 2 words (5%) were related to frusemide diuretic.
d. Keywords related to Renal Diseases
Six renal diseases were considered and related keywords are used to search articles. Out of 29 keywords,9 words (30%) were correlated with renal obstructions, 8 words (28%) were related to renovascular hypertension, 4+4 words (28%) were related to renal transplantations,2+2 words (14%) were associated with renal stenosis.
3.2 Research Type
While reviewing various published articles different categories were considered and articles are classified according to availability of required data base, types of data analysis, various methodologies, their applications and limitations, statistical and quantitative analysis using several principles, case studies related to different renal diseases etc. After classification of articles, only articles that are related to renal scan imaging and signal processing techniques along with quantitative and statistical conceptual analysis are focused for reviewing purpose.