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Research article
Investigation on antibody level of umbilical cord blood measles in 2017 in ankang city, Shaanxi province, China
Chunge Wan
Ankang City Center for for Disease Control and Prevention
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
Background Through the examination and analysis of the level of the antibody against the umbilical cord blood measles in maternal newborn in ankang city, to explore prevention and control measures and strategies of measles.
Methods Using indirect enzyme-linked immunoadsorption testto test the level of Measles IgG antibody in 848 randomly collected neonatal umbilical cord blood samples,and Using descriptive epidemiological methods,Enter relevant data into Microsoft Excel to establish a database,Statistical analysis using SPSS.
Results The positive rate of measles IgG antibody was 84.43 % in 848 neonatal umbilical cord blood samples in Ankang City.There is no statistical difference in the positive rate of neonatal umbilical cord blood measles IgG antibody in different age groups（P>0.05）,However, the positive rate of neonatal umbilical cord blood measles IgG showed a decreasing trend with the increase of maternal age;Maternal and newborn umbilical cord blood measles IgG antibody positive rate and different forms of residence, different maternal births has nothing to do with,but it is related to the county and district where it is located and the vaccination service model.In the counties where the quality of vaccination services is good, and in the areas where the township vaccination service model is implemented, the positive rate of maternal newborn umbilical cord blood measles IgG antibodies is higher, and the difference is statistically significant(P & lt; 0.05).
Conclusions Vaccination of measles ingredients before pregnancy in women of childbearing age can not only increase the level of measles antibodies in people of childbearing age, but also increase the level of measles antibodies in infants born in August before the birth of Mazhenyimiao, thus effectively reducing the incidence of measles in children over 15 years of age and within the age of 8 months.It is of great significance to strengthen the standardized administration of vaccination, adjust the vaccination service model, and vigorously promote the centralized vaccination service model in townships and towns to reduce the incidence of measles.
Keywords
Umbilical cord blood, Measles immunoglobulinG antibody, Seroepidemiology
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This is a preprint. It has not completed peer review.
Research article
Investigation on antibody level of umbilical cord blood measles in 2017 in ankang city, Shaanxi province, China
Chunge Wan
Ankang City Center for for Disease Control and Prevention
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 15 Jan, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background Through the examination and analysis of the level of the antibody against the umbilical cord blood measles in maternal newborn in ankang city, to explore prevention and control measures and strategies of measles.
Methods Using indirect enzyme-linked immunoadsorption testto test the level of Measles IgG antibody in 848 randomly collected neonatal umbilical cord blood samples,and Using descriptive epidemiological methods,Enter relevant data into Microsoft Excel to establish a database,Statistical analysis using SPSS.
Results The positive rate of measles IgG antibody was 84.43 % in 848 neonatal umbilical cord blood samples in Ankang City.There is no statistical difference in the positive rate of neonatal umbilical cord blood measles IgG antibody in different age groups（P>0.05）,However, the positive rate of neonatal umbilical cord blood measles IgG showed a decreasing trend with the increase of maternal age;Maternal and newborn umbilical cord blood measles IgG antibody positive rate and different forms of residence, different maternal births has nothing to do with,but it is related to the county and district where it is located and the vaccination service model.In the counties where the quality of vaccination services is good, and in the areas where the township vaccination service model is implemented, the positive rate of maternal newborn umbilical cord blood measles IgG antibodies is higher, and the difference is statistically significant(P & lt; 0.05).
Conclusions Vaccination of measles ingredients before pregnancy in women of childbearing age can not only increase the level of measles antibodies in people of childbearing age, but also increase the level of measles antibodies in infants born in August before the birth of Mazhenyimiao, thus effectively reducing the incidence of measles in children over 15 years of age and within the age of 8 months.It is of great significance to strengthen the standardized administration of vaccination, adjust the vaccination service model, and vigorously promote the centralized vaccination service model in townships and towns to reduce the incidence of measles.