Typology
|
Indicator
|
Effective-ness
|
Efficiency
|
Equity
|
Patient-centered
|
Safety
|
Timeliness
|
Outcome
|
1PN rate (ICSI)
|
x
|
x
|
|
|
|
|
|
1PN rate (IVF)
|
x
|
x
|
|
|
|
|
|
Achievement of the minimum standards for the KPIs established for monitoring laboratory performance by consensus papers per month
|
x
|
x
|
|
|
|
|
|
Average number of intended retrievals per new patient
|
x
|
x
|
|
|
|
|
|
Average number of transfers per intended retrieval
|
x
|
x
|
|
|
|
|
|
Blastocyst development rate
|
x
|
x
|
|
|
|
|
|
C-LBR
|
x
|
x
|
|
|
|
|
|
Cleavage rate
|
x
|
x
|
|
|
|
|
|
Cleavage rate for ICSI-fertilized cryopreserved oocytes.
|
x
|
x
|
|
|
|
|
|
CPR
|
x
|
x
|
|
|
|
|
|
Cumulative ART success rates
|
x
|
x
|
|
|
|
|
|
Day 2 embryo development rate
|
x
|
x
|
|
|
|
|
|
Day 3 embryo development rate
|
x
|
x
|
|
|
|
|
|
Day-5 blastulation rate
|
x
|
x
|
|
|
|
|
|
Drugs for stimulation: GnRH agonist, GnRH antagonist, clomiphene citrate
|
x
|
x
|
|
|
|
|
|
Egg donations from the related/known donors
|
x
|
x
|
|
|
|
|
|
Embryo morphology data
|
x
|
x
|
|
|
|
|
|
Embryos donated for research
|
x
|
x
|
|
|
|
|
|
ET - Difficult transfers
|
x
|
x
|
|
|
|
|
|
ET - Retained embryos
|
x
|
x
|
|
|
|
|
|
Failed fertilization rate (IVF)
|
x
|
x
|
|
|
|
|
|
Fertilization rate
|
x
|
x
|
|
|
|
|
|
Fertilization rate of cryopreserved oocytes by ICSI.
|
x
|
x
|
|
|
|
|
|
Good blastocyst development rate
|
x
|
x
|
|
|
|
|
|
ICSI damage rate
|
x
|
x
|
|
|
|
|
|
ICSI normal fertilization rate
|
x
|
x
|
|
|
|
|
|
Implantation rate (blastocyst stage)
|
x
|
x
|
|
|
|
|
|
Implantation rate (cleavage stage)
|
x
|
x
|
|
|
|
|
|
Implantation rate for cryopreserved blastocysts (women <38 years).
|
x
|
x
|
|
|
|
|
|
Implantation rate for post-cryopreservation embryos (women <38 years).
|
x
|
x
|
|
|
|
|
|
IVF normal fertilization rate
|
x
|
x
|
|
|
|
|
|
IVF polyspermy rate
|
x
|
x
|
|
|
|
|
|
LBR
|
x
|
x
|
|
|
|
|
|
MII oocytes rate
|
x
|
x
|
|
|
|
|
|
Miscarriage rate
|
x
|
x
|
|
|
|
|
|
number of double embryo transfer in ED cycles
|
x
|
x
|
|
|
|
|
|
Number of eggs shared between the donor and the recipient (anonymous or related)
|
x
|
x
|
|
|
|
|
|
Number of eggs shared between the donor and the recipient.
|
x
|
x
|
|
|
|
|
|
Number of intended retrievals per live birth
|
x
|
x
|
|
|
|
|
|
Number of oocytes
|
x
|
x
|
|
|
|
|
|
OPR
|
x
|
x
|
|
|
|
|
|
OPU % Hemorrhage
|
|
|
|
|
x
|
|
|
OPU % Oocytes retrieved/mature follicles
|
x
|
x
|
|
|
|
|
|
OPU % Other complication requiring hospitalization
|
|
|
|
|
x
|
|
|
OPU % Pelvic infection
|
|
|
|
|
x
|
|
|
OS % Cancelled retrieval
|
x
|
x
|
|
|
|
|
|
OS % OHSS
|
|
|
|
|
x
|
|
|
OS % Retrieval failure (no oocytes)
|
x
|
x
|
|
|
|
|
|
Percentage of retrievals resulting in singleton live births
|
x
|
x
|
|
|
|
|
|
Percentage of cycles cancelled prior to retrieval or thaw
|
x
|
x
|
|
|
|
|
|
Percentage of cycles for fertility preservation
|
x
|
x
|
|
|
|
|
|
Percentage of cycles stopped between retrieval and transfer or banking
|
x
|
x
|
|
|
|
|
|
Percentage of intended retrievals resulting in live births
|
x
|
x
|
|
|
|
|
|
Percentage of intended retrievals resulting in singleton live births
|
x
|
x
|
|
|
|
|
|
Percentage of new patients having live births after 1 intended retrieval
|
x
|
x
|
|
|
|
|
|
Percentage of new patients having live births after 1 or 2 intended retrievals
|
x
|
x
|
|
|
|
|
|
Percentage of new patients having live births after all intended retrievals
|
x
|
x
|
|
|
|
|
|
Percentage of retrievals resulting in live births
|
x
|
x
|
|
|
|
|
|
Percentage of transfers of at least one embryo with ICSI
|
x
|
x
|
|
|
|
|
|
Percentage of transfers of at least one embryo with PGT
|
x
|
x
|
|
|
|
|
|
Percentage of transfers resulting in live births
|
x
|
x
|
|
|
|
|
|
Percentage of transfers resulting in singleton live births
|
x
|
x
|
|
|
|
|
|
Percentage of transfers using a gestational carrier
|
x
|
x
|
|
|
|
|
|
Percentage of transfers using frozen embryos
|
x
|
x
|
|
|
|
|
|
Proportion of ART births among all births
|
X
|
|
|
|
|
|
|
Proportion of blastocysts that are more-or-less intact post cryopreservation.
|
X
|
x
|
|
|
|
|
|
Proportion of blastocysts that re-expand within 3 h post cryopreservation.
|
x
|
x
|
|
|
|
|
|
Proportion of early blastocysts post cryopreservation that expand during overnight culture prior to embryo transfer.
|
x
|
x
|
|
|
|
|
|
Proportion of embryos with >=50% blastomeres intact post cryopreservation.
|
x
|
x
|
|
|
|
|
|
Proportion of embryos with all blastomeres intact post cryopreservation.
|
x
|
x
|
|
|
|
|
|
Proportion of MII oocytes at ICSI
|
x
|
x
|
|
|
|
|
|
Proportion of oocyte retrieval cycles that have blastocysts suitable for freezing.
|
x
|
x
|
|
|
|
|
|
Proportion of oocyte retrieval cycles that have embryos suitable for freezing.
|
x
|
x
|
|
|
|
|
|
Proportion of oocyte retrieval cycles that have zygotes for freezing.
|
x
|
x
|
|
|
|
|
|
Proportion of oocytes recovered
|
x
|
x
|
|
|
|
|
|
Proportion of oocytes that are intact post cryopreservation.
|
x
|
x
|
|
|
|
|
|
Proportion of post-cryopreservation embryos that cleave during overnight culture.
|
x
|
x
|
|
|
|
|
|
Proportion of post-cryopreservation zygotes that cleave during overnight culture.
|
x
|
x
|
|
|
|
|
|
Proportion of zygotes that appear intact post cryopreservation.
|
x
|
x
|
|
|
|
|
|
SIR
|
x
|
x
|
|
|
|
|
|
Sperm motility post-preparation
|
x
|
x
|
|
|
|
|
|
Success Rates for ART Transfers Among Patients Using Eggs or Embryos from a Donor: Percentage of transfers resulting in live births
|
x
|
x
|
|
|
|
|
|
Success Rates for ART Transfers Among Patients Using Eggs or Embryos from a Donor: Percentage of transfers resulting in singleton live births
|
x
|
x
|
|
|
|
|
|
Successful biopsy rate
|
x
|
x
|
|
|
|
|
|
Thawing survival
|
x
|
x
|
|
|
|
|
|
The number of fresh ART cycles with complications (OHSS, hemorrhage, infection) as a result of MAR relative to the total number of fresh ART cycles during a certain time period
|
|
|
|
|
x
|
|
|
The number of fresh ART cycles with severe complications (OHSS, bleeding, infection, complaints of serious pain) resulting from the fertility treatment, which require hospitalization relative to the total number of fresh ART cycles during a certain time period
|
|
|
|
|
x
|
|
|
The number of live births (the complete expulsion or extraction of a product of fertilization that shows evidence of life) after a fresh ART cycle with embryo transfer relative to the total number of fresh ART cycles with embryo transfer during a certain time period
|
X
|
|
|
|
|
|
|
The number of patients who after a maximum of three fresh ART cycles (oocyte aspiration actually performed) had a live birth (the expulsion or extraction of minimally one fetus showing evidence of life) relative to the total number of patients starting an ART cycle during a certain time period
|
X
|
|
|
|
|
|
|
The number of pregnancies in women younger than 36 years old as a result of a fresh ART cycle relative to the total amount of fresh ART cycles in women younger than 36 years old during a certain time period
|
X
|
|
|
|
|
|
|
The number of treated patients who go home with a live born baby relative to the total number of treated patients during a certain time period
|
X
|
|
|
|
|
|
|
Total service volume of IVF/ICSI/FET/PGD
|
x
|
x
|
|
|
|
|
|
Twin PR
|
x
|
x
|
|
|
|
|
Process
|
Average duration of gamete/embryo manipulations in minutes
|
|
x
|
|
|
|
x
|
|
gonadotropins Total dose
|
x
|
x
|
|
|
|
|
|
gonadotropins Type
|
x
|
x
|
|
|
|
|
|
Inter-operator agreement in oocyte/embryo morphological grading
|
x
|
x
|
|
|
|
|
|
Interval between the scheduled and the effective time for a given procedure
|
|
x
|
|
|
|
x
|
|
Intrauterine insemination: IUI-H, IUI-D
|
x
|
x
|
|
|
|
|
|
Number of accidents (e.g., gamete/embryo loss during denudation) per operator relative to the total number of ART procedures conducted in a given time period
|
x
|
|
|
|
x
|
|
|
Number of ART clinics reporting data on their ART services
|
|
x
|
|
|
|
|
|
Number of identified mistakes (e.g., mislabeled samples) per operator relative to the total number of ART procedures conducted in a given time period
|
x
|
|
|
|
x
|
|
|
Percentage of laboratory staff injuries while handling liquid nitrogen per number of ART procedures per year
|
|
|
|
|
x
|
|
|
Proportion of fragments lysed or lost after embryo biopsy
|
x
|
x
|
|
|
|
|
|
Reason for Using ART
|
|
x
|
|
x
|
|
|
|
The average duration of the waiting time during MAR per patient between having the need for and attending an urgent consultation in case of unexpected negative results (e.g. fertilization failure) during a certain time period
|
|
|
|
|
|
x
|
|
The average duration of the waiting time in the waiting room per patient between the agreed time to start a consultation and actual starting time of the consultation during a certain time period
|
|
|
|
|
|
x
|
|
The average duration of the waiting time per new patient between the asking and the getting of the first appointment during a certain time period
|
|
|
|
|
|
x
|
|
The average duration of the waiting time per patient between the first appointment and the start of the first treatment cycle during a certain time period
|
|
|
|
|
|
x
|
|
The number of cross-contamination or operator infections per number of ART procedures conducted with infectious material
|
|
|
|
|
x
|
|
|
The number of MAR cycles in which gametes or embryos get lost as a result of an accident, human error or mistake relative to the total number of MAR cycles during a certain time period
|
|
|
|
|
x
|
|
|
The number of patients of a fertility clinic to whom psychosocial counselling was offered relative to the total number of patients of that fertility clinic during a certain time period
|
|
|
|
x
|
|
|
|
The number of patients undergoing a very thorough diagnostic phase and reaching a diagnosis prior to starting MAR relative to the total number of patients starting MAR during a certain time period
|
|
x
|
|
|
|
|
|
The number of patients who opinionated that she/he is being respected by her/his physician relative to the total number of interrogated patients during a certain time period
|
|
|
X
|
|
|
|
|
The number of patients who opinionated that their personal experiences and wishes were actually heard relative to the total number of interrogated patients during a certain time period
|
|
|
|
x
|
|
|
|
The number of reported mistakes or incidents caused by all care providers relative to the number of treatment cycles during a certain time period
|
|
|
|
|
x
|
|
|
The percentage of donor egg recipients of more than 55 years of age
|
x
|
x
|
|
|
|
|
|
Time elapsed between drop deposition and oil coverage during dish preparation
|
|
x
|
|
|
|
x
|
|
Type of cycle in relation to: Oocytes, Fresh, non-donor, fresh, donor cycle, sharing cycle, thaw cycle non-donor, thaw cycle donor, fresh recipient cycle
|
x
|
x
|
|
|
|
|
|
Type of Cycle: Long, short, Natural, substituted, other
|
x
|
x
|
|
|
|
|
Structural
|
Achievement of competency values established by consensus papers (e.g., Vienna consensus KPIs for fresh IVF and ICSI cycles or Alpha KPIs for oocyte and embryo cryopreservation) per operator per month
|
x
|
x
|
|
|
|
|
|
Average time required to move a dish or sample from a place to another
|
x
|
|
|
|
X
|
|
|
Clinic Current Services
|
|
x
|
|
x
|
|
|
|
Ever-use of any infertility services
|
|
x
|
|
|
|
|
|
Number of approved clinics providing ART services
|
|
x
|
|
|
|
|
|
Number of ART cycles being performed
|
|
x
|
|
|
|
|
|
Number of ART cycles per million population per year
|
|
x
|
|
|
|
|
|
Number of clinics providing cryopreservation
|
|
x
|
|
|
|
|
|
Number of clinics providing fertility preservation
|
|
x
|
|
|
|
|
|
Number of clinics providing GIFT cycles
|
|
x
|
|
|
|
|
|
Number of clinics providing ICSI
|
|
x
|
|
|
|
|
|
Number of clinics providing PGT (PGD/PGS) services
|
|
x
|
|
|
|
|
|
Number of CPD credits per operator per year
|
x
|
x
|
|
|
|
|
|
Number of critical instruments (e.g., incubators, safety cabinets, micromanipulators) relative to the total number of ART procedures conducted in a given time period
|
x
|
|
|
|
x
|
|
|
Number of operators relative to the total number of ART procedures conducted in a given time period
|
x
|
|
|
|
x
|
|
|
Number of unscheduled maintenance interventions relative to the total number planned per year
|
x
|
|
|
|
x
|
|
|
Percent increase in ART cycles per million population per year
|
|
x
|
|
|
|
|
|
Percentage of accidents during handlings relative to the total number of ART procedures conducted in a given time period
|
x
|
|
|
|
x
|
|
|
Percentage of staff injuries in a given time period relative to the total number of ART procedures conducted
|
|
|
|
|
x
|
|
|
The existence of a website of the fertility clinic containing all the basic information, contracts and information about studies and FAQs at a certain moment in time
|
|
x
|
|
|
|
|
|
The provision of a clearly explained vision of the fertility clinic concerning ethical limitations of which at no time nor for no reason can be deviated at a certain moment in time
|
|
|
x
|
|
|
|
|
The provision of clearly described in- and exclusion criteria for MAR in the fertility clinic (among others taking into account the national legislation) at a certain moment in time
|
|
|
x
|
|
|
|
|
The provision of protocols that are in accordance with international guidelines/recommendations of care concerning equity and taking account of the universal needs at a certain moment in time
|
|
|
x
|
|
|
|
|
The provision of the offer to patients of psychosocial counselling at a certain moment in time
|
|
|
|
x
|
|
|
|
The provision of the use of an electronic patient record containing all relevant clinical information and allowing the extraction of letters and reports at a certain moment in time
|
|
x
|
|
|
|
|
|
The regular organization of a multidisciplinary meeting of the fertility clinic in which the psychosocial context of the patient can be discussed if necessary during a certain time period
|
|
|
|
x
|
|
|
|
The total number of FTE care providers relative to the total number of treated patients per type of care provider during a certain time period
|
|
x
|
|
|
|
|