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Research article
Vladimir Berthaud
Meharry Medical College
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5585-4853
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A wealth of scientific evidence supports the effectiveness of HIV prophylaxis and treatment. Homelessness has become one of the strongest predictors of health status and viral suppression among vulnerable populations and can undermine the national plan to eliminate HIV by 2030. This retrospective observational study examined the extent in which homelessness affects HIV treatment in an underserved urban area of Middle Tennessee in 2014-2019. Among 692 HIV-seropositive patients, the proportion of homeless patients increased from 13.5% to 27.7%, thrice the national average for HIV-seropositive people (8.4%) and twice that of Ryan White patients nationwide (12.9%). Our findings suggest that homeless patients were half as likely to achieve viral suppression as compared to those who had a permanent/stable home OR 0.48 (0.32-0.72), p-value <0.001. The alarming rate of homelessness in this population raises serious concerns for long-term HIV treatment outcomes and the trajectory of the syndemic of homelessness and HIV.
Keywords
Homelessness, HIV, social determinants, and viral suppression
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CURRENT STATUS: Under Review
Version 1
Posted 02 Dec, 2020
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Reviewer #2 agreed
On 21 Dec, 2020
Reviewer #1 agreed
On 20 Dec, 2020
Reviewers invited
Invitations sent on 18 Dec, 2020
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On 29 Nov, 2020
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On 26 Nov, 2020
Editor invited
On 25 Nov, 2020
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Infectious Diseases
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A new preprint design is coming!
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This preprint is under consideration at BMC Infectious Diseases. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Vladimir Berthaud
Meharry Medical College
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5585-4853
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 02 Dec, 2020
No community comments so far
Reviewer #2 agreed
On 21 Dec, 2020
Reviewer #1 agreed
On 20 Dec, 2020
Reviewers invited
Invitations sent on 18 Dec, 2020
Editor assigned
On 29 Nov, 2020
Submission checks complete
On 26 Nov, 2020
Editor invited
On 25 Nov, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Infectious Diseases
License:
This work is licensed under a CC BY 4.0 License. Read Full License
A wealth of scientific evidence supports the effectiveness of HIV prophylaxis and treatment. Homelessness has become one of the strongest predictors of health status and viral suppression among vulnerable populations and can undermine the national plan to eliminate HIV by 2030. This retrospective observational study examined the extent in which homelessness affects HIV treatment in an underserved urban area of Middle Tennessee in 2014-2019. Among 692 HIV-seropositive patients, the proportion of homeless patients increased from 13.5% to 27.7%, thrice the national average for HIV-seropositive people (8.4%) and twice that of Ryan White patients nationwide (12.9%). Our findings suggest that homeless patients were half as likely to achieve viral suppression as compared to those who had a permanent/stable home OR 0.48 (0.32-0.72), p-value <0.001. The alarming rate of homelessness in this population raises serious concerns for long-term HIV treatment outcomes and the trajectory of the syndemic of homelessness and HIV.
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