See the published version of this preprint at Scientific Reports.
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Research Article
Akihiko Kida
JA Toyama Kouseiren Takaoka Hospital
Corresponding Author
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【Background】 There is limited evidence demonstrating the usefulness of endoscopic retrograde pancreatic drainage (ERPD) for symptomatic pancreaticojejunal anastomotic stenosis (sPJS). We examined the usefulness of ERPD for sPJS.
【Methods】 We conducted a retrospective analysis of 10 benign sPJS patients. Following items were evaluated: technical success, adverse events and clinical outcome of ERPD.
【Results】 Technical success rate was 100% (10/10); 9 patients had a pancreatic stent (no-internal-flap: n=4, internal-flap: n=5). Median follow-up was 920 days. Four patients developed recurrence. Among them, 3 patients had a stent with no-internal-flap in initial ERPD and the stent migrated in 3 patients at recurrence, and a stent was not placed in 1 patient in initial ERPD. Four follow-up ERPD were performed. No recurrence was observed in 6 patients. Among them, none of the stents migrated (no-internal-flap: n=1, internal-flap: n=5), and none were replaced stents due to stent failure. A stent placement with no-internal-flap was associated with recurrence (p=0.042). Mild adverse events developed in 14.3% (2/14).
【Conclusions】 ERPD was performed safely with high technical success. Recurrence was common in a stent placement with no-internal-flap, which was associated with stent migration. Long-term stent placement didn’t result in stent failure.
Keywords
pancreaticojejunostomy, anastomotic stenosis, endoscopic retrograde pancreatic drainage, pancreatic stent
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CURRENT STATUS: Published
View the published article at Scientific Reports.
Version 1
Posted 09 Dec, 2020
No community comments so far
Editorial decision: Major revision
On 28 Dec, 2020
Reviews received
Received 20 Dec, 2020
Reviewers agreed
On 08 Dec, 2020
Reviewers invited
Invitations sent on 08 Dec, 2020
Editor assigned
On 08 Dec, 2020
Editor invited
On 02 Dec, 2020
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On 02 Dec, 2020
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On 01 Dec, 2020
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Subject Areas
Gastroenterology & Hepatology
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See the published version of this preprint at Scientific Reports.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Akihiko Kida
JA Toyama Kouseiren Takaoka Hospital
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Scientific Reports.
Version 1
Posted 09 Dec, 2020
No community comments so far
Editorial decision: Major revision
On 28 Dec, 2020
Reviews received
Received 20 Dec, 2020
Reviewers agreed
On 08 Dec, 2020
Reviewers invited
Invitations sent on 08 Dec, 2020
Editor assigned
On 08 Dec, 2020
Editor invited
On 02 Dec, 2020
Submission checks complete
On 02 Dec, 2020
First submitted
On 01 Dec, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Gastroenterology & Hepatology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Scientific Reports.
【Background】 There is limited evidence demonstrating the usefulness of endoscopic retrograde pancreatic drainage (ERPD) for symptomatic pancreaticojejunal anastomotic stenosis (sPJS). We examined the usefulness of ERPD for sPJS.
【Methods】 We conducted a retrospective analysis of 10 benign sPJS patients. Following items were evaluated: technical success, adverse events and clinical outcome of ERPD.
【Results】 Technical success rate was 100% (10/10); 9 patients had a pancreatic stent (no-internal-flap: n=4, internal-flap: n=5). Median follow-up was 920 days. Four patients developed recurrence. Among them, 3 patients had a stent with no-internal-flap in initial ERPD and the stent migrated in 3 patients at recurrence, and a stent was not placed in 1 patient in initial ERPD. Four follow-up ERPD were performed. No recurrence was observed in 6 patients. Among them, none of the stents migrated (no-internal-flap: n=1, internal-flap: n=5), and none were replaced stents due to stent failure. A stent placement with no-internal-flap was associated with recurrence (p=0.042). Mild adverse events developed in 14.3% (2/14).
【Conclusions】 ERPD was performed safely with high technical success. Recurrence was common in a stent placement with no-internal-flap, which was associated with stent migration. Long-term stent placement didn’t result in stent failure.
Figure 1
Figure 1
Figure 2
Figure 2
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