In order to perform their daily activities, a person is required to communicating with others. This can be a major obstacle for the deaf population of the world, who communicate using sign languages (SL). Pakistani Sign Language (PSL) is used by more than 250,000 deaf Pakistanis. Developing a SL recognition system would greatly facilitate these people. This study aimed to collect data of static and dynamic PSL alphabets and to develop a vision-based system for their recognition using Bag-of-Words (BoW) and Support Vector Machine (SVM) techniques. A total of 5,120 images for 36 static PSL alphabet signs and 353 videos with 45,224 frames for 3 dynamic PSL alphabet signs were collected from 10 native signers of PSL. The developed system used the collected data as input, resized the data to various scales and converted the RGB images into grayscale. The resized grayscale images were segmented using Thresholding technique and features were extracted using Speeded Up Robust Feature (SURF). The obtained SURF descriptors were clustered using K-means clustering. A BoW was obtained by computing the Euclidean distance between the SURF descriptors and the clustered data. The codebooks were divided into training and testing using 5-fold cross validation. The highest overall classification accuracy for static PSL signs was 97.80% at 750×750 image dimensions and 500 Bags. For dynamic PSL signs a 96.53% accuracy was obtained at 480×270 video resolution and 200 Bags.