It is unusual for filariasis to affect the breast, but it is not unusual for parasitic worms to infest or transmit in the breast (Parashar et al. 2020). The effects of filariasis can be both systemic and subcutaneous. Chronic filariasis can lead to enlargement and hardening of tissues, or elephantiasis, and is caused by swelling of tissues. (Shenoy. 2008). A whopping 120 million people in the world are currently suffering from filariasis and more than a billion are at risk of infection (Gordon et al. 2018). Microfilaria have been found in the tissues of the thyroid, soft tissues, breasts, hydrocele fluid, and cervical smears. Microfilaria have also been found in the tumour fluid of patients with various cancer types according to Prasoon et al. (2020). Lymphatic filariasis is a major public health issue in tropical countries such as India, China, the West Indies, Japan, and parts of Africa. (Singh et al. 2004). The disease is profoundly disfiguring visible manifestations all over India, especially in states like Pondicherry, Tamil nadu, Uttar Pradesh, Bihar, Jharkhand, Andhra Pradesh, Orissa, Kerala, and Gujarat (Parija and Garg 2010). Filaria disease is caused by pathogenic nematodes which primarily cause inflammation of lymph nodes, fever, and lymphedema (Makepeace et al. 2012). Microfilaria may be sheathed or unsheathed. Microfilaremia, Microfilaria load, and Microfilaria bancrofti are the sheathed microfilaria that has apparent envelope surrounding microfilariae infixed and stained blood smears (Mathison et al. 2019). Microfilariae perstans and Micro-filariaeozzardi fall into the unsheathed category (Brothwell 1967). Microfilaria have been detected on fine needle aspiration cytology (FNAC) at different sites like lymph node, thyroid, liver, lungs, breast and small number of cases have been reported in the bone marrow and body fluids (Sinha et al. 2014). However, Singh et al (2011) also reported that filariasis presenting as a subcutaneous nodule is very rare. A majority of infected individuals are asymptomatic especially in filarial endemic communities (Manego et al. 2017). The conventional mode of diagnosis of filariasis is by demonstration of microfilaria in peripheral blood smear. Despite the high incidence, it is infrequent to find microfilariae on FNAC smears and body fluids (Gupta 2021). There are only a few reports in the literature with significant numbers of breast filariasis cases diagnosis of breast filariasis with fibroadenoma-like lesions. In the present study, we presented a rare case identification of microfilarial nodule over the breast.