1 N. Zhang, L. Li, P. Wang et al., "Pharmacokinetics of the main compounds absorbed into blood after oral administration of Liu Wei Di Huang Wan, a typical combinatorial intervention of Chinese medical formula," J Nat Med, vol. 67, no. 1,pp.36-41,2013.
2 S. Chakraborty, J. C. Lennon, S. A. Malkaram, Y. Zeng, D. W. Fisher, H. Dong, "Serotonergic system, cognition, and BPSD in Alzheimer's disease," NEUROSCIENCE LETTERS, vol. 704, no.,pp.36-44,2019.
3 N. Eissa, A. Sadeq, A. Sasse, B. Sadek, "Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD?" Frontiers in Pharmacology, vol. 11, no.,pp.886,2020.
4 L. Tang, Y. Wang, Y. Chen et al., "The Association between 5HT2A T102C and Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease: A Meta-Analysis," Biomed Research International, vol. 2017, no.,pp.5320135,2017.
5 S. Lopez-Leon, A. C. Janssens, L. A. Gonzalez-Zuloeta et al., "Meta-analyses of genetic studies on major depressive disorder," Mol Psychiatry, vol. 13, no. 8,pp.772-85,2008.
6 B. M, P. E, "The role of Serotonin Receptors in Alzheimer’s disease," Opera Medica & Physiologica, vol., no. １,pp.89-98.
7 C. H. Lin, H. Y. Lane, "The Role of N-Methyl-D-Aspartate Receptor Neurotransmission and Precision Medicine in Behavioral and Psychological Symptoms of Dementia," Frontiers in Pharmacology, vol. 10, no.,pp.540,2019.
8 Y. Chen, Y. Xian, Z. Lai, S. Loo, W. Y. Chan, Z. X. Lin, "Anti-inflammatory and anti-allergic effects and underlying mechanisms of Huang-Lian-Jie-Du extract: Implication for atopic dermatitis treatment," JOURNAL OF ETHNOPHARMACOLOGY, vol. 185, no.,pp.41-52,2016.
9 J Shi, J Ni, J Tian. et al., "A systematic review on heat-clearing and toxicity-removing therapy for Alzheimer's disease," Bei Jing Zhong Yi Yao Da Xue Xue Bao, vol. 42, no. 08,pp.667-72,2019.
10 G. Stelzer, N. Rosen, I. Plaschkes et al., "The GeneCards Suite: From Gene Data Mining to Disease Genome Sequence Analyses," Curr Protoc Bioinformatics, vol. 54, no.,pp.1-30,2016.
11 P. Shannon, A. Markiel, O. Ozier et al., "Cytoscape: a software environment for integrated models of biomolecular interaction networks," GENOME RESEARCH, vol. 13, no. 11,pp.2498-504,2003.
12 G. Bindea, B. Mlecnik, H. Hackl et al., "ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks," BIOINFORMATICS, vol. 25, no. 8,pp.1091-3,2009.
13 M. F. Sanner, "Python: a programming language for software integration and development," JOURNAL OF MOLECULAR GRAPHICS & MODELLING, vol. 17, no. 1,pp.57-61,1999.
14 R. Chen, P. T. Chan, H. Chu et al., "Treatment effects between monotherapy of donepezil versus combination with memantine for Alzheimer disease: A meta-analysis," PLoS One, vol. 12, no. 8,pp.e183586,2017.
15 A. Bucki, M. Marcinkowska, J. Sniecikowska et al., "Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD)," EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 191, no.,pp.112149,2020.
16 N. M. O'Boyle, M. Banck, C. A. James, C. Morley, T. Vandermeersch, G. R. Hutchison, "Open Babel: An open chemical toolbox," J Cheminform, vol. 3, no.,pp.33,2011.
17 L. Ma, X. Zhang, X. Xu et al., "Compatibility principle in the Tanyu Tongzhi Formula revealed by a cell-based analysis," JOURNAL OF ETHNOPHARMACOLOGY, vol. 231, no.,pp.507-15,2019.
18 R. Yuan, Y. Lin, "Traditional Chinese medicine: an approach to scientific proof and clinical validation," Pharmacol Ther, vol. 86, no. 2,pp.191-8,2000.
19 R. Fujikawa, S. Higuchi, M. Nakatsuji et al., "Deficiency in EP4 Receptor-Associated Protein Ameliorates Abnormal Anxiety-Like Behavior and Brain Inflammation in a Mouse Model of Alzheimer Disease," AMERICAN JOURNAL OF PATHOLOGY, vol. 187, no. 8,pp.1848-54,2017.
20 C. Villegas-Llerena, A. Phillips, P. Garcia-Reitboeck, J. Hardy, J. M. Pocock, "Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease," CURRENT OPINION IN NEUROBIOLOGY, vol. 36, no.,pp.74-81,2016.
21 F. Yin, H. Sancheti, I. Patil, E. Cadenas, "Energy metabolism and inflammation in brain aging and Alzheimer's disease," Free Radic Biol Med, vol. 100, no.,pp.108-22,2016.
22 L. Guo, H. Zhang, W. Li, D. Zhan, M. Wang, "N-acetyl cysteine inhibits lipopolysaccharide-mediated induction of interleukin-6 synthesis in MC3T3-E1 cells through the NF-kB signaling pathway," ARCHIVES OF ORAL BIOLOGY, vol. 93, no.,pp.149-54,2018.
23 F. V. Gomes, R. Llorente, B. E. Del, M. P. Viveros, M. Lopez-Gallardo, F. S. Guimaraes, "Decreased glial reactivity could be involved in the antipsychotic-like effect of cannabidiol," SCHIZOPHRENIA RESEARCH, vol. 164, no. 1-3,pp.155-63,2015.
24 Y. Baumer, S. McCurdy, M. Alcala et al., "CD98 regulates vascular smooth muscle cell proliferation in atherosclerosis," ATHEROSCLEROSIS, vol. 256, no.,pp.105-14,2017.
25 M. D. Sweeney, K. Kisler, A. Montagne, A. W. Toga, B. V. Zlokovic, "The role of brain vasculature in neurodegenerative disorders," NATURE NEUROSCIENCE, vol. 21, no. 10,pp.1318-31,2018.
26 Y. Zhou, A. Yasumoto, C. Lei et al., "Intelligent classification of platelet aggregates by agonist type," eLife, vol. 9, no.,2020.
27 J. Tejero, S. Shiva, M. T. Gladwin, "Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation," PHYSIOLOGICAL REVIEWS, vol. 99, no. 1,pp.311-79,2019.
28 M. Forcella, P. Lau, M. Oldani et al., "Neuronal specific and non-specific responses to cadmium possibly involved in neurodegeneration: A toxicogenomics study in a human neuronal cell model," NEUROTOXICOLOGY, vol. 76, no.,pp.162-73,2020.
29 X. Wen, D. J. Klionsky, "An overview of macroautophagy in yeast," JOURNAL OF MOLECULAR BIOLOGY, vol. 428, no. 9 Pt A,pp.1681-99,2016.
30 D. Paterson, A. Nordberg, "Neuronal nicotinic receptors in the human brain," PROGRESS IN NEUROBIOLOGY, vol. 61, no. 1,pp.75-111,2000.
31 T. Teaktong, A. J. Graham, M. Johnson, J. A. Court, E. K. Perry, "Selective changes in nicotinic acetylcholine receptor subtypes related to tobacco smoking: an immunohistochemical study," Neuropathol Appl Neurobiol, vol. 30, no. 3,pp.243-54,2004.
32 J. Tian, J. Shi, M. Wei et al., "Chinese herbal medicine Qinggongshoutao for the treatment of amnestic mild cognitive impairment: A 52-week randomized controlled trial," Alzheimers Dement (N Y), vol. 5, no.,pp.441-9,2019.
33 J. Shi, M. Wei, J. Ni et al., "Tianzhi granule improves cognition and BPSD of vascular dementia: a randomized controlled trial," Journal of Translational Medicine, vol. 18, no. 1,pp.76,2020.