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Research Article
Barbara Machado
Anglia Ruskin University
Corresponding Author
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Background: Measuring outcomes from treatments to the skin is either reliant upon patient’s subjective feedback or scale-based peer assessments. Three-Dimensional stereophotogrammetry intend to accurately quantify skin microtopography before and after treatments.
Objective: To compare the accuracy of stereophotogrammetry and a scale-based peer evaluation in assessing topographical changes to skin surface following laser treatment.
Methods: A 3D stereophotogrammetry system photographed skin surface of 48 patients with facial wrinkles or scars before and three months after laser resurfacing, followed immediately by topical application of vitamin C. The software measured changes in skin roughness, wrinkle depth and scar volume. Images were presented to three observers, each independently scoring cutaneous improvement according to Investigator Global Aesthetic Improvement Scale (IGAIS) Scale.
Results: A trend reflecting skin/scar improvement was reported by 3D-SPM measurements and raters. The percentage of topographical change given by the raters matched 3D SPM findings. Agreement was highest when observers analyzed 3D images. However, observers overestimated skin improvement in a nontreatment control whilst 3D-SPM was precise in detecting absence of intervention.
Conclusion: This study confirmed a direct correlation between the IGAIS clinical scale and 3D-SPM and confirmed the efficacy and accuracy of the latter when assessing cutaneous microtopography alterations as a response to laser treatment.
Keywords
clinical scale, IGAIS, laser skin resurfacing, laser-assisted drug delivery, skin roughness, scar relief, scar roughness, scar volume, scar treatment, skin wrinkle, skin microtopography, three-dimensional stereophotogrammetry
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CURRENT STATUS: Under Review
Version 1
Posted 04 Jan, 2021
No community comments so far
Editorial decision: Major revision
On 23 Mar, 2021
Reviews received
Received 24 Feb, 2021
Reviewers agreed
On 22 Feb, 2021
Reviewers agreed
On 19 Feb, 2021
Reviewers invited
Invitations sent on 16 Feb, 2021
Editor assigned
On 16 Feb, 2021
Editor invited
On 29 Dec, 2020
Submission checks complete
On 29 Dec, 2020
First submitted
On 10 Dec, 2020
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A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
This preprint is under consideration at Scientific Reports. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Barbara Machado
Anglia Ruskin University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 04 Jan, 2021
No community comments so far
Editorial decision: Major revision
On 23 Mar, 2021
Reviews received
Received 24 Feb, 2021
Reviewers agreed
On 22 Feb, 2021
Reviewers agreed
On 19 Feb, 2021
Reviewers invited
Invitations sent on 16 Feb, 2021
Editor assigned
On 16 Feb, 2021
Editor invited
On 29 Dec, 2020
Submission checks complete
On 29 Dec, 2020
First submitted
On 10 Dec, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Measuring outcomes from treatments to the skin is either reliant upon patient’s subjective feedback or scale-based peer assessments. Three-Dimensional stereophotogrammetry intend to accurately quantify skin microtopography before and after treatments.
Objective: To compare the accuracy of stereophotogrammetry and a scale-based peer evaluation in assessing topographical changes to skin surface following laser treatment.
Methods: A 3D stereophotogrammetry system photographed skin surface of 48 patients with facial wrinkles or scars before and three months after laser resurfacing, followed immediately by topical application of vitamin C. The software measured changes in skin roughness, wrinkle depth and scar volume. Images were presented to three observers, each independently scoring cutaneous improvement according to Investigator Global Aesthetic Improvement Scale (IGAIS) Scale.
Results: A trend reflecting skin/scar improvement was reported by 3D-SPM measurements and raters. The percentage of topographical change given by the raters matched 3D SPM findings. Agreement was highest when observers analyzed 3D images. However, observers overestimated skin improvement in a nontreatment control whilst 3D-SPM was precise in detecting absence of intervention.
Conclusion: This study confirmed a direct correlation between the IGAIS clinical scale and 3D-SPM and confirmed the efficacy and accuracy of the latter when assessing cutaneous microtopography alterations as a response to laser treatment.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
The full text of this article is available to read as a PDF.
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