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Research Article
Comparative Study of Children's' Blood Sugar in Fluid Therapy with Dextrose Saline, Ringer and Normal Saline 9.0% Serums and its Relationship with Depth of Anesthesia in Elective Surgery
Zohreh sekhavatpour
Dezful University of Medical sciences, Dezful, Iran
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: This study was aimed to determine the children's' blood sugar level in fluid therapy with DSS, RSand NS 0.9% serums and its relationship with the depth of anesthesia in elective surgery.
Method: This double-blind experimental study was performed with 90 children referred to the surgical ward, including: group A (receiving DSS), group B (receiving NS 0.9%) and group C (receiving RS) that the blood sugar of each group in 5 steps was measured: half an hour before induction of anesthesia, during induction of anesthesia, half and one hour after induction of anesthesia and after complete awakening in recovery. In addition, the monitoring the vital signs, measuring depth of anesthesia, pulse oximetry and electrocardiogram were performed for all groups.
Results: The results showed that the mean blood sugar in the 5 steps measured had a significant difference in three groups under study (P <0.05). The mean blood sugar in the group receiving DSS was significantly higher than the two groups receiving RS and NS 0.9%. Also the mean depth of anesthesia in three groups did not show a significant difference.
Conclusion: Finally, according to this study, the use of DSS from the beginning of anesthesia, RS half an hour after the start of anesthesia and NS 0.9% one hour after the start of anesthesia can increase blood sugar in children. Therefore, the use of DSS is not recommended due to the stressful nature of anesthesia and operating room and the possibility of hyperglycemia.
Keywords
Anesthesia, Blood sugar, Child, BIS, Elective Surgery, Ringer Serum, Dextrose Saline Serum, Normal Saline 0.9%.
Due to technical limitations, table 1,2,3,4,5,6,7,8 is only available as a download in the Supplemental Files section.
This is a list of supplementary files associated with this preprint. Click to download.
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CURRENT STATUS: Under Review
Version 1
Posted 05 Jan, 2021
No community comments so far
Review #1 received
Received 24 Jan, 2021
Review #3 received
Received 24 Jan, 2021
Review #2 received
Received 24 Jan, 2021
Reviewer #12 agreed
On 15 Jan, 2021
Reviewer #14 agreed
On 15 Jan, 2021
Reviewer #1 agreed
On 15 Jan, 2021
Reviewer #3 agreed
On 15 Jan, 2021
Reviewer #2 agreed
On 15 Jan, 2021
Reviewer #11 agreed
On 15 Jan, 2021
Reviewer #4 agreed
On 15 Jan, 2021
Reviewer #13 agreed
On 15 Jan, 2021
Reviewer #10 agreed
On 15 Jan, 2021
Reviewers invited
Invitations sent on 10 Jan, 2021
Editor assigned
On 10 Jan, 2021
Editor invited
On 01 Jan, 2021
Submission checks complete
On 01 Jan, 2021
First submitted
On 15 Dec, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Anesthesiology & Pain Medicine
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This preprint is under consideration at BMC Anesthesiology. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Comparative Study of Children's' Blood Sugar in Fluid Therapy with Dextrose Saline, Ringer and Normal Saline 9.0% Serums and its Relationship with Depth of Anesthesia in Elective Surgery
Zohreh sekhavatpour
Dezful University of Medical sciences, Dezful, Iran
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 05 Jan, 2021
No community comments so far
Review #1 received
Received 24 Jan, 2021
Review #3 received
Received 24 Jan, 2021
Review #2 received
Received 24 Jan, 2021
Reviewer #12 agreed
On 15 Jan, 2021
Reviewer #14 agreed
On 15 Jan, 2021
Reviewer #1 agreed
On 15 Jan, 2021
Reviewer #3 agreed
On 15 Jan, 2021
Reviewer #2 agreed
On 15 Jan, 2021
Reviewer #11 agreed
On 15 Jan, 2021
Reviewer #4 agreed
On 15 Jan, 2021
Reviewer #13 agreed
On 15 Jan, 2021
Reviewer #10 agreed
On 15 Jan, 2021
Reviewers invited
Invitations sent on 10 Jan, 2021
Editor assigned
On 10 Jan, 2021
Editor invited
On 01 Jan, 2021
Submission checks complete
On 01 Jan, 2021
First submitted
On 15 Dec, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Anesthesiology & Pain Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: This study was aimed to determine the children's' blood sugar level in fluid therapy with DSS, RSand NS 0.9% serums and its relationship with the depth of anesthesia in elective surgery.
Method: This double-blind experimental study was performed with 90 children referred to the surgical ward, including: group A (receiving DSS), group B (receiving NS 0.9%) and group C (receiving RS) that the blood sugar of each group in 5 steps was measured: half an hour before induction of anesthesia, during induction of anesthesia, half and one hour after induction of anesthesia and after complete awakening in recovery. In addition, the monitoring the vital signs, measuring depth of anesthesia, pulse oximetry and electrocardiogram were performed for all groups.
Results: The results showed that the mean blood sugar in the 5 steps measured had a significant difference in three groups under study (P <0.05). The mean blood sugar in the group receiving DSS was significantly higher than the two groups receiving RS and NS 0.9%. Also the mean depth of anesthesia in three groups did not show a significant difference.
Conclusion: Finally, according to this study, the use of DSS from the beginning of anesthesia, RS half an hour after the start of anesthesia and NS 0.9% one hour after the start of anesthesia can increase blood sugar in children. Therefore, the use of DSS is not recommended due to the stressful nature of anesthesia and operating room and the possibility of hyperglycemia.
Due to technical limitations, table 1,2,3,4,5,6,7,8 is only available as a download in the Supplemental Files section.