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Comparison of Clinical Features and Prognosis of Severe Fever With Thrombocytopenia Syndrome Transmitted From Tick-to-person Versus Person-to-person
Jianghua Yang
Yijishan Hospital of Wannan Medical College
Corresponding Author
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Background: Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne infection that has recently emerged. It is important to compare the clinical features and prognosis of severe fever with thrombocytopenia syndrome transmitted from tick-to-person versus person-to-person.
Methods: A retrospective analysis of the confirmed cases of SFTS from 2015 to 2020 in southern Anhui was performed according to the different transmission routes. The cases were divided into a tick-to-person transmission infection group (37 cases) and a person-to-person transmission infection group (12 cases).
Results: SFTS incidence was concentrated in April-June.The median time from onset to treatment was 2.5 days in the person-to-person transmission infection group and 5.0 days in the tick-to-person transmission infection group (P<0.05). The proportion of consciousness disorders in the tick-to-person transmission infection group was 43.24% (16/37), which was higher than that in the person-to-person transmission infection group. The number of critical patients in the person-to-person transmission group was 16.67% (2/12), which was significantly lower than that in the tick-to-person transmission infection group, 91.89% (34/37). The number of deaths in the tick-to-person transmission infection group was 29.73% (11/37), but there were no deaths in the person-to-person transmission infection group.
Conclusions: The tick-to-person transmission infection group is more serious, and the risk of poor prognosis is higher in this group. Therefore, we should scientifically formulate prevention and control strategies and treatment plans for patients with tick infections.
Keywords
Severe fever with thrombocytopenia syndrome, Person-to-person transmission, New bunyavirus, Prognosis
Figure 1
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CURRENT STATUS: Under Review
Version 1
Posted 18 Dec, 2020
No community comments so far
Review #1 received
Received 26 Dec, 2020
Reviewers invited
Invitations sent on 20 Dec, 2020
Reviewer #1 agreed
On 20 Dec, 2020
Editor assigned
On 14 Dec, 2020
Submission checks complete
On 14 Dec, 2020
Editor invited
On 14 Dec, 2020
First submitted
On 11 Dec, 2020
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Subject Areas
Virology
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This preprint is under consideration at Virology Journal. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Comparison of Clinical Features and Prognosis of Severe Fever With Thrombocytopenia Syndrome Transmitted From Tick-to-person Versus Person-to-person
Jianghua Yang
Yijishan Hospital of Wannan Medical College
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 18 Dec, 2020
No community comments so far
Review #1 received
Received 26 Dec, 2020
Reviewers invited
Invitations sent on 20 Dec, 2020
Reviewer #1 agreed
On 20 Dec, 2020
Editor assigned
On 14 Dec, 2020
Submission checks complete
On 14 Dec, 2020
Editor invited
On 14 Dec, 2020
First submitted
On 11 Dec, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Virology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne infection that has recently emerged. It is important to compare the clinical features and prognosis of severe fever with thrombocytopenia syndrome transmitted from tick-to-person versus person-to-person.
Methods: A retrospective analysis of the confirmed cases of SFTS from 2015 to 2020 in southern Anhui was performed according to the different transmission routes. The cases were divided into a tick-to-person transmission infection group (37 cases) and a person-to-person transmission infection group (12 cases).
Results: SFTS incidence was concentrated in April-June.The median time from onset to treatment was 2.5 days in the person-to-person transmission infection group and 5.0 days in the tick-to-person transmission infection group (P<0.05). The proportion of consciousness disorders in the tick-to-person transmission infection group was 43.24% (16/37), which was higher than that in the person-to-person transmission infection group. The number of critical patients in the person-to-person transmission group was 16.67% (2/12), which was significantly lower than that in the tick-to-person transmission infection group, 91.89% (34/37). The number of deaths in the tick-to-person transmission infection group was 29.73% (11/37), but there were no deaths in the person-to-person transmission infection group.
Conclusions: The tick-to-person transmission infection group is more serious, and the risk of poor prognosis is higher in this group. Therefore, we should scientifically formulate prevention and control strategies and treatment plans for patients with tick infections.
Figure 1