Jejunoileal diverticulosis is rare; reported in 1-2 percent of the population.The first report of jejunal diverticula dates back to 1807 by Sir Astley Cooper.Incidence rates ranges from 0.3 to 1.3% in autopsy series and 2.3% in imaging studies; reported cases are even fewer in number. Jejunal diverticula are usually acquired, false diverticula, and multiple in number.They occur at the mesenteric border in contrast to a true congenital Meckel’s diverticulum.
Various theories have been proposed to explain the occurrence of jejunal diverticula. One theory proposed deficiency of dietary fibre causing abnormalities in intestinal peristalsis with pseudo-obstruction resulting in higher intraluminal pressure. Areas of focal smooth muscle weakness, at entry point of blood vessels,has also been discussed as a cause for diverticulosis. Another theory postulates that an abnormal mesenteric plexus induced smooth muscle dysfunction and uncoordinated peristalsis leads to localized areas of high pressure and subsequent diverticulosis.,  Krishnamurthy et al. reported jejunal diverticulosis to be a consequence of abnormalities in either the smooth muscle of bowel wall or myenteric plexus. In their study, pathological examination revealed smooth muscle changes consistent with progressive systemic sclerosis or visceral myopathy and myenteric plexus neuronal changes similar to familial visceral neuropathy.
Most of the patients with jejunal diverticulosis are asymptomatic; acute or chronic symptoms reported by 10-19% of patients. Symptomatic patients tend to be in their 7th -8th decade with a male preponderance.Nearly 60% of symptomatic patients have chronic complaints related to intestinal motility or intestinal malabsorption and misdiagnosed as dyspepsia or irritable bowel syndrome. In 10-20% of patients, acute complications such as diverticulitis, perforation, obstruction, and bleeding can occur. Obstruction due to jejunal diverticulosis occurs in 2.3-4.6% of cases.
Cause of obstruction include inflammatory mass, stricture or adhesions due to diverticulitis, volvulus due to meso-diverticular band, intussusceptions due to enterolith and extrinsic compression of an intestinal loop with a large diverticula.Large size of the jejunal diverticula (>3cm)could predispose to midgut volvulus.
Due to the non-specific complaints encountered in small bowel diverticulosis, diagnosis is generally arrived after radiological investigation. The first radiological diagnosis of jejunoileal diverticulosis was reported on barium contrast study in 1915. In current era, ultrasound is usually the first investigation which can detect bowel wall thickening with hypoechoic rim and hyperechoic centre. However, in case of acute presentation like obstruction or perforation, X-ray is usually the first investigation with no further investigation required depending on X-ray findings and clinical condition of the patient. Given the low sensitivity and operator dependence of ultrasound, CECT has become the investigation of choice. Administration of oral and intravenous contrast increases the sensitivity. Oral contrast is used to assess bowel wall thickening, stricture formation or intra-luminal mass and intravenous contrast detects inflammatory changes. Moreover, CECT has shown higher sensitivity for complications like diverticulitis, obstruction, perforation, intussusceptions, volvulus and intra-abdominal abscess. However, imaging may miss half of symptomatic small bowel diverticula prior to surgery. Device-assisted enteroscopy and capsule endoscopy have emerged as attractive options for detection of jejunal diverticulosis in patients with non-specific symptoms. However they are contraindicated in patients presenting with complicated jejunal diverticulosis. 
Surgical management is required in 8.5% of all patients with jejunal diverticulosis which is more frequent in patients with symptomatic diverticulosis associated with complications. Surgical excision with end to end anastomosis is the ideal procedure to be done in jejunal diverticulosis with perforation, necrosis or stenosis due to inflamed diverticula. The length of bowel resection must be limited to the area of bowel containing inflamed diverticula to avoid complications of short bowel syndrome in cases of diffuse small bowel diverticulosis. Diverticulectomy should be avoided in view of high failure rate.
There is no evidence at present to treat asymptomatic diverticulosis detected incidentally. Patients with symptomatic diverticulosis presenting with chronic abdominal pain or malabsorption are treated conservatively with a combination of analgesics, anti-diarrheal agents with anti-spasmodic agents with variable success rate. In symptoms suggestive of bacterial overgrowth, oral antibiotics such as tetracycline and erythromycin are prescribed. Patients presenting with mild diverticulitis can undergo a trial of conservative management with bowel rest and parenteral antibiotics. Rate of recurrence is high with conservative management and hence the primary pathology to be addressed once the inflammation subsides. In the event of diverticular perforation with peridiverticular abscess or collection less than 5 cm, CT guided drainage with parenteral antibiotics is provided. However, recurrence is common with patients returning with symptoms after hospital discharge and requiring admission. The number of studies with patients managed conservatively for complications of jejunal diverticulosis is less due to the low incidence of jejunal diverticulosis.
Jejunal diverticulosis is a rare condition encountered in the elderly population with patients who are asymptomatic or having non-specific symptoms. However knowledge of small diverticulosis especially of its associated complications of obstruction, perforation and bleeding should be remembered as a differential diagnosis when encountering patients in this age group in an emergency setting. Patients with vague abdominal symptoms or recurrent symptoms in this age group need to be evaluated further. Wider use and advances of CT enteroclysis, capsule endoscopy and device assisted enteroscopy may pick up the disease earlier. Although rare, small bowel diverticulosis should not be treated as insignificant.