Case No.
|
Location of recurrence
|
Imaging findings at recurrence
|
Post-relapse treatment procedure
|
2nd surgical pathology
|
Radiotherapy
|
Survival time after relapse (months)
|
Prognosis
|
1
|
Right retroperitoneum, lung
|
CT showed masses during chemotherapy
|
After surgery, 9 sessions of alternate chemotherapy (CBP+VP16 AND CTX+VCR+ADM)
|
Blastemal
|
3d-crt 10.8 gy
|
30
|
Treatment finish, survival
|
2
|
Left retroperitoneum
|
CT showed occupying lesions in the left renal region, multiple small lymph nodes in the retroperitoneum
|
Preoperative chemotherapy: 4 sessions of VAA regimen. Postoperative chemotherapy :ACT+VDS regimen
|
Mesenchymal
|
3d-crt 10.8 gy
|
31
|
Treatment finish, survival
|
3
|
Right retroperitoneum
|
CT revealed a mass
|
Two sessions of preoperative chemotherapy; standardized postoperative chemotherapy
|
Unclassified
|
3d-crt 10.8 gy
|
39
|
Treatment finish,survival
|
4
|
Left upper pulmonary lobe
|
Regular CT examination revealed a mass
|
Two sessions of preoperative chemotherapy, high-risk regimen. After surgical removal of lung metastatic lesions, standardized postoperative chemotherapy was performed, high-risk regimen.
|
Unclassified
|
3d-crt 10.8 gy
|
67
|
Treatment finish,survival
|
5
|
Right lower pulmonary lobe (1st recurrence), right lower pleura (2nd), brain (3rd)
|
Regular CT examination revealed a mass
|
Two sessions of preoperative chemotherapy, high-risk regimen. After surgical removal of lung metastatic lesion, 4 sessions of postoperative chemotherapy, CAV regimen. Standardized postoperative chemotherapy was performed for the metastasis of right lower pleura.
|
Necrotic tissue
|
2MRT 10.8 Gy
|
18
|
Dead, cause: left frontal lobe cerebral hemorrhage (acute phase)
|
6
|
Abdominal aortic, right renal lymph nodes
|
Regular CT examination revealed a mass
|
Five sessions of alternate CAV/CE chemotherapy and standardized postoperative chemotherapy
|
Mesenchymal
|
3D-CRT 10.8 Gy
|
25
|
Treatment finish, survival
|
7
|
Right residual kidney
|
Regular CT examination revealed a mass
|
One session of preoperative chemotherapy (VCR+ACTD+ADM)
|
Necrotic tissue
|
None
|
36
|
Treatment finish,survival
|
8
|
Intraperitoneal, lymph nodes of right ventricular diaphragmatic wall, pleura, peritoneum and abdominal multiple metastases
|
CT showed abdominal effusion; swollen lymph nodes at right palpebral area
|
Two sessions of postoperative chemotherapy (carboplatin+VP16)
|
NA
|
Whole abdominal radiotherapy,3D-CRT, 30 Gy
|
9
|
Dead, cause: peritoneal metastasis,severe intestinal obstruction vomiting, electrolyte imbalance
|
9
|
Extensive peritoneal metastasis
|
B ultrasound showed abdominal effusion
|
Abdominal puncture showed bloody ascites. Exploratory laparotomy revealed extensive peritoneal metastasis.
|
Mesenchymal
|
Whole abdominal radiotherapy,3d-crt 10.5 gy
|
2
|
Dead, cause: extensive intraperitoneal metastases
|
10
|
Right abdomen
|
B ultrasound showed right abdominal mass
|
Six sessions of postoperative chemotherapy (carboplatin+VP16)
|
Necrotic tissue
|
Right-flank abdominal radiotherapy, 21.6Gy
|
132
|
Treatment finish,survival
|
11
|
Left retroperitoneum, Abdominal aorta, inferior vena cava
|
Regular MRI examination revealed a mass
|
Surgical resection
|
Unclassified
|
None
|
108
|
Treatment finish,survival
|
12
|
Liver, extensive peritoneal metastasis
|
NA
|
After two session of chemotherapy, patient still developed extensive peritoneal metastasis, and then the patient gave up the treatment.
|
Na
|
None
|
4
|
Dead, cause: extensive intraperitoneal metastases
|
13
|
Retroperitoneum, Pelvic large tumor invading into L4 S3 spinal canal and L5/S1 spinal cord
|
Identifying a mass 6 months after treatment
|
Four sessions of alternate chemotherapy for anaplastic Wilms tumor (CBP+VP16) and (CTX+VCR+ADM), tumor size was not reduced. Tumor cannot be removed by surgery.
|
Unclassified
|
None
|
38
|
Dead, cause: tumor invasion of the spinal canal and spinal cord
|
14
|
Extensive peritoneal pelvic metastasis
|
B-ultrasound revealed a mass after chemotherapy
|
Five sessions of preoperative chemotherapy, but extensive peritoneal metastasis could not be radically excised.
|
Mixed
|
Whole abdominal radiotherapy;3d-crt 12.6 gy
|
8
|
Dead, cause: extensive intraperitoneal metastases
|