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Case report
Sclerosing Angiomatoid Nodular Transformation of the Spleen, a Rare Cause for Laparoscopic Splenectomy: a Case Report and Literature Review
Tianchong Wu
Shenzhen People's Hospital
Corresponding Author
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BACKGROUND: Sclerosing angiomatoid nodular transformation of the spleen is one kind of exceedingly rare benign lesions originated from spleen. The incidence and pathogen remain unclear partially due to its rarity and short history. Consequently, preoperative diagnosis become extremely perplex. Splenectomy is a predominated therapy approach as well as diagnosis method for sclerosing angiomatoid nodular transformation of the spleen. We reported a case underwent computed tomography scan, magnetic resonance imaging and ultrasonic scan preoperatively. Examinations conclusion highly suspected sclerosing angiomatoid nodular transformation of the spleen and was confirmed by pathology after laparoscopic splenectomy. We herein reviewed some literatures on imaging characters of to reveal the possibility of preoperative diagnosis when clinicians encounter and investigated whether laparoscopic splenectomy is an appropriate treatment.
CASE PRESENTATION: A 50-year-old female was found with a low dense mass in the spleen by abdominal computed tomography incidentally without any positive symptom. Further enhanced computed tomography scan revealed the lesion with asynchronous enhancement and magnetic resonance imaging showed radio-like rift missing from central. Ultrasonic scan imaging presented hypoechoic gap in the center, pretty similar to magnetic resonance imaging. These radiology imaging features deduced to Sclerosing angiomatoid nodular transformation of the spleen. Laparoscopic splenectomy was performed successfully by our team and histopathological findings convinced the preoperative diagnosis. Gross inspection was coincident to the performance of magnetic resonance imaging.
CONCLUSION: By comprehending imaging character profoundly, sclerosing angiomatoid nodular transformation of the spleen can be a differential diagnosis preoperatively when encounter lesion of spleen. We believe that laparoscopic splenectomy is a reliable and effective therapy option for such rare benign lesion of spleen without risk of recurrence.
Keywords
SANT, laparoscopic splenectomy, case report
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CURRENT STATUS: Under Review
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Posted 30 Dec, 2020
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Reviewer #4 agreed
On 09 Jan, 2021
Reviewer #3 agreed
On 08 Jan, 2021
Review #1 received
Received 07 Jan, 2021
Reviewer #2 agreed
On 06 Jan, 2021
Reviewer #1 agreed
On 06 Jan, 2021
Reviewers invited
Invitations sent on 29 Dec, 2020
Submission checks complete
On 25 Dec, 2020
Editor assigned
On 24 Dec, 2020
Editor invited
On 24 Dec, 2020
First submitted
On 21 Dec, 2020
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This preprint is under consideration at World Journal of Surgical Oncology. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Case report
Sclerosing Angiomatoid Nodular Transformation of the Spleen, a Rare Cause for Laparoscopic Splenectomy: a Case Report and Literature Review
Tianchong Wu
Shenzhen People's Hospital
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 30 Dec, 2020
No community comments so far
Reviewer #4 agreed
On 09 Jan, 2021
Reviewer #3 agreed
On 08 Jan, 2021
Review #1 received
Received 07 Jan, 2021
Reviewer #2 agreed
On 06 Jan, 2021
Reviewer #1 agreed
On 06 Jan, 2021
Reviewers invited
Invitations sent on 29 Dec, 2020
Submission checks complete
On 25 Dec, 2020
Editor assigned
On 24 Dec, 2020
Editor invited
On 24 Dec, 2020
First submitted
On 21 Dec, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
BACKGROUND: Sclerosing angiomatoid nodular transformation of the spleen is one kind of exceedingly rare benign lesions originated from spleen. The incidence and pathogen remain unclear partially due to its rarity and short history. Consequently, preoperative diagnosis become extremely perplex. Splenectomy is a predominated therapy approach as well as diagnosis method for sclerosing angiomatoid nodular transformation of the spleen. We reported a case underwent computed tomography scan, magnetic resonance imaging and ultrasonic scan preoperatively. Examinations conclusion highly suspected sclerosing angiomatoid nodular transformation of the spleen and was confirmed by pathology after laparoscopic splenectomy. We herein reviewed some literatures on imaging characters of to reveal the possibility of preoperative diagnosis when clinicians encounter and investigated whether laparoscopic splenectomy is an appropriate treatment.
CASE PRESENTATION: A 50-year-old female was found with a low dense mass in the spleen by abdominal computed tomography incidentally without any positive symptom. Further enhanced computed tomography scan revealed the lesion with asynchronous enhancement and magnetic resonance imaging showed radio-like rift missing from central. Ultrasonic scan imaging presented hypoechoic gap in the center, pretty similar to magnetic resonance imaging. These radiology imaging features deduced to Sclerosing angiomatoid nodular transformation of the spleen. Laparoscopic splenectomy was performed successfully by our team and histopathological findings convinced the preoperative diagnosis. Gross inspection was coincident to the performance of magnetic resonance imaging.
CONCLUSION: By comprehending imaging character profoundly, sclerosing angiomatoid nodular transformation of the spleen can be a differential diagnosis preoperatively when encounter lesion of spleen. We believe that laparoscopic splenectomy is a reliable and effective therapy option for such rare benign lesion of spleen without risk of recurrence.
Figure 1
Figure 2
Figure 3
Figure 4