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Acute Effect of Particulate Matter Pollution on Hospital Admissions for Stroke among Patients with type 2 Diabetes in Beijing, China, from 2014 to 2018
Xiuhua Guo
School of Public Health, Capital Medical University
Corresponding Author
ORCiD: https://orcid.org/0000-0001-6657-6940
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This work is licensed under a CC BY 4.0 License. Read Full License
Background: The health effect of particulate matter pollution on stroke has been widely examined; however, the effect among patients with comorbid type 2 diabetes (T2D) in developing countries has remained largely unknown.
Methods: A time-series study was conducted to investigate the short-term effect of fine particulate matter (PM2.5) and inhalable particulate matter (PM10) on hospital admissions for stroke among patients with T2D in Beijing, China, from 2014 to 2018. An over-dispersed Poisson generalized additive model was employed to adjust for important covariates, such as weather conditions and long-term and seasonal trends.
Results: A total of 159,298 (58% male) hospital admissions for stroke were reported. Linear exposure-response curves were observed for PM2.5 and PM10 in relation to stroke admissions among T2D patients. A 10 μg/m3 increase in the four-day moving average of PM2.5 and PM10 was associated with 0.14% (95% confidence interval [CI]: 0.05%-0.23%) and 0.14% (95% CI: 0.06%-0.22%) incremental increases in stroke admissions among T2D patients, respectively. A 10 μg/m3 increase in PM2.5 in the two-day moving average corresponded to a 0.72% (95% CI: 0.02%-1.42%) incremental increase in hemorrhagic stroke, and a 10 μg/m3 increase in PM10 in the four-day moving average corresponded to a 0.14% (95% CI: 0.06%-0.22%) incremental increase in ischemic stroke.
Conclusions: High particulate matter might be a risk factor for stroke among patients with T2D. PM2.5 and PM10 have a linear exposure-response relationship with stroke among T2D patients. The study provided evidence of the risk of comorbid T2D and stroke due to particulate matter pollution.
Keywords
Particulate matter, Stroke, Type 2 diabetes, Comorbidities
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Research
Acute Effect of Particulate Matter Pollution on Hospital Admissions for Stroke among Patients with type 2 Diabetes in Beijing, China, from 2014 to 2018
Xiuhua Guo
School of Public Health, Capital Medical University
Corresponding Author
ORCiD: https://orcid.org/0000-0001-6657-6940
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 05 Jan, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The health effect of particulate matter pollution on stroke has been widely examined; however, the effect among patients with comorbid type 2 diabetes (T2D) in developing countries has remained largely unknown.
Methods: A time-series study was conducted to investigate the short-term effect of fine particulate matter (PM2.5) and inhalable particulate matter (PM10) on hospital admissions for stroke among patients with T2D in Beijing, China, from 2014 to 2018. An over-dispersed Poisson generalized additive model was employed to adjust for important covariates, such as weather conditions and long-term and seasonal trends.
Results: A total of 159,298 (58% male) hospital admissions for stroke were reported. Linear exposure-response curves were observed for PM2.5 and PM10 in relation to stroke admissions among T2D patients. A 10 μg/m3 increase in the four-day moving average of PM2.5 and PM10 was associated with 0.14% (95% confidence interval [CI]: 0.05%-0.23%) and 0.14% (95% CI: 0.06%-0.22%) incremental increases in stroke admissions among T2D patients, respectively. A 10 μg/m3 increase in PM2.5 in the two-day moving average corresponded to a 0.72% (95% CI: 0.02%-1.42%) incremental increase in hemorrhagic stroke, and a 10 μg/m3 increase in PM10 in the four-day moving average corresponded to a 0.14% (95% CI: 0.06%-0.22%) incremental increase in ischemic stroke.
Conclusions: High particulate matter might be a risk factor for stroke among patients with T2D. PM2.5 and PM10 have a linear exposure-response relationship with stroke among T2D patients. The study provided evidence of the risk of comorbid T2D and stroke due to particulate matter pollution.
Figure 1
Figure 2
Figure 3
Figure 4