The neutral of this study is to examine the human capital effect on Liberia’s economic growth and empirically estimates the contribution of human capital accumulation within the Liberian economy from 2000 to 2019. We used a time-series data of linear regression (OLS) model where data is taken from the World Bank Development Indicators to test our observed variables using the Eviews7 statistical tool. The final linear regression model displayed Population (POP) growth rate as a positive and significant factor for GNI accumulation, while the model predicates government HEALTH expenditure, LIFE expectancy at birth, and foreign AID to be negative and not significant statistically. The result raises a concern that low expenditure on health could cause limited life expectancy and also hinder the attainment of human capital while placing the overall labor force at risk in the Liberian economy.