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Shengyu Wang
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4382-0530
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Background
Temperature and air pollution has been reported to be associated with respiratory diseases. However, little is known about these effects on healthy people, and the potential interaction between the two factors is still uncertain. This study aims to estimate the effects of air pollution combined with temperature on lung function in healthy people.
Methods
The lung function of 132 healthy people was measured in Xi’an, Shaanxi province of Northwest China in summer and winter. Meanwhile, the daily concentrations of air pollution and temperature were obtained from monitoring stations. Statistical analyses were assessed by generalized estimating equations (GEEs).
Results
Every 10μg/m 3 increase of PM 2.5 concentration, PEF change amount is -0.007L/min (95% CI: -0.013, -0.001 L/min), FEV1 is -0.004 (95% CI: -0.006, -0.001 L/min),FEF25-75% is -0.002(95% CI: -0.003, -0.001 L/min) FEV1/FVC change amount is -0.074 L/min (95% CI: -0.115, -0.033 L/min). Lag effects showed that Lag0 of FEV1, FEV1/FVC and FEF25-75% were more strongly associated with PM2.5. There was no significant interaction between PM 2.5 and temperature.
Conclusions
Our findings indicate that PM 2.5 has an acute adverse effect on lung function in winter, and the lung function is less affected by temperature change in Xi’an.
Keywords
Temperature, Air pollution, Respiratory function texts, Adult, China
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Shengyu Wang
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4382-0530
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
The most recent version of this article is available here.
No community comments so far
Version 1
Posted 13 Feb, 2020
No comments provided
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
The most recent version of this article is available here.
Background
Temperature and air pollution has been reported to be associated with respiratory diseases. However, little is known about these effects on healthy people, and the potential interaction between the two factors is still uncertain. This study aims to estimate the effects of air pollution combined with temperature on lung function in healthy people.
Methods
The lung function of 132 healthy people was measured in Xi’an, Shaanxi province of Northwest China in summer and winter. Meanwhile, the daily concentrations of air pollution and temperature were obtained from monitoring stations. Statistical analyses were assessed by generalized estimating equations (GEEs).
Results
Every 10μg/m 3 increase of PM 2.5 concentration, PEF change amount is -0.007L/min (95% CI: -0.013, -0.001 L/min), FEV1 is -0.004 (95% CI: -0.006, -0.001 L/min),FEF25-75% is -0.002(95% CI: -0.003, -0.001 L/min) FEV1/FVC change amount is -0.074 L/min (95% CI: -0.115, -0.033 L/min). Lag effects showed that Lag0 of FEV1, FEV1/FVC and FEF25-75% were more strongly associated with PM2.5. There was no significant interaction between PM 2.5 and temperature.
Conclusions
Our findings indicate that PM 2.5 has an acute adverse effect on lung function in winter, and the lung function is less affected by temperature change in Xi’an.
Figure 1
Figure 2
Figure 3
This is a list of supplementary files associated with this preprint. Click to download.
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