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Shengyu Wang
The First Affiliated Hospital of Xi’an Medical University
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4382-0530
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This work is licensed under a CC BY 4.0 License. Read Full License
Background: Temperature and air pollution has been reported to be associated with respiratory diseases. However, little is known about these effects on healthy people, and the potential interaction between the two factors is still uncertain. This study aims to estimate the effects of air pollution combined with temperature on lung function in healthy people.
Methods: The lung function of 428 healthy people was measured in Xi’an, Shaanxi province of Northwest China in summer and winter. Meanwhile, the daily concentrations of air pollution and temperature were obtained from monitoring stations. Statistical analyses were assessed by generalized estimating equations (GEEs).
Results: In winter, Every 10μg/m 3 increase of PM 2.5 concentration, PEF change amount is -0.015L/S(-0.028,-0.002), FEV1 is -0.007 L/S(-0.012,-0.001). The change is -0.022(-0.043,-0.001) and -0.010(-0.011,-0.009) after adjusting for SO 2 . In summer, PEF and FEV1 were were negatively correlated with the concontration of O3. We also found that temperature weaken the adverse effect of PM 2.5 on lung PEF in winter but aggravated effect of O3 on FEV1 in summer. Lag effects showed that Lag0 of FEV1, FEV1/FVC and FEF25-75% were more strongly associated with PM 2.5 .
Conclusions: Our findings indicate that Lung function was significantly negative correlated with O3 in summer and PM 2.5 in winter, and a higher temperature has a greater impact on lung function in both summer and winter in Xi’an.
Keywords
Temperature, Air pollution, Respiratory function texts, Adult, China
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Shengyu Wang
The First Affiliated Hospital of Xi’an Medical University
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4382-0530
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 2
Posted 14 Jul, 2020
No community comments so far
No comments provided
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Temperature and air pollution has been reported to be associated with respiratory diseases. However, little is known about these effects on healthy people, and the potential interaction between the two factors is still uncertain. This study aims to estimate the effects of air pollution combined with temperature on lung function in healthy people.
Methods: The lung function of 428 healthy people was measured in Xi’an, Shaanxi province of Northwest China in summer and winter. Meanwhile, the daily concentrations of air pollution and temperature were obtained from monitoring stations. Statistical analyses were assessed by generalized estimating equations (GEEs).
Results: In winter, Every 10μg/m 3 increase of PM 2.5 concentration, PEF change amount is -0.015L/S(-0.028,-0.002), FEV1 is -0.007 L/S(-0.012,-0.001). The change is -0.022(-0.043,-0.001) and -0.010(-0.011,-0.009) after adjusting for SO 2 . In summer, PEF and FEV1 were were negatively correlated with the concontration of O3. We also found that temperature weaken the adverse effect of PM 2.5 on lung PEF in winter but aggravated effect of O3 on FEV1 in summer. Lag effects showed that Lag0 of FEV1, FEV1/FVC and FEF25-75% were more strongly associated with PM 2.5 .
Conclusions: Our findings indicate that Lung function was significantly negative correlated with O3 in summer and PM 2.5 in winter, and a higher temperature has a greater impact on lung function in both summer and winter in Xi’an.
Figure 1
Figure 2
Figure 3
Figure 4
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