During this period, a total of 61 countries have published articles on this research field, and China (Circulation = 238) is the country with the largest contribution, followed by the United States (Circulation = 103), France (Circulation = 32), Britain (Circulation = 30) and Australia (Circulation = 23),in Fig. 3A,B and Table 1. And from 2006 to 2021, more than 385 institutions published articles in this field. Capital Med Univ was the institution with the most publications(34),as shown in Table 2.
Authors Analysis
As shown in Fig. 3C and Table 3, during the period from 2006 to 2021, more than 504 authors published articles, among which DABAO XU was considered the most active author in this field, with the largest number of articles (number = 10), XINGPING ZHAO the second most (number = 9), HUA DUAN (number = 8), HUAN HUANG (number = 7), LU GAN (number = 7), and they are closely related.
Table 3
Top 10 authors by publishing frequency.Year indicates the number of years in which articles were first published, and count indicates the number of articles published during this period.
NO. | Authors | Year | Count |
1 2 3 4 5 6 7 8 9 10 | DABAO XU XINGPING ZHAO HUA DUAN LU GAN HUAN HUANG AIQIAN ZHANG SONGYING ZHANG BINGSI GAO XIAONA LIN ANGELO B HOOKER | 2015 2020 2016 2016 2020 2015 2018 2020 2018 2015 | 10 9 8 7 7 6 6 6 6 5 |
Keyword Analysis
A total of 465 keywords were obtained from 614 literatures, and a co-occurrence map of keywords was drawn,as shown in Fig. 4A. Among them, the ten most frequently used keywords were intrauterine adhesionis (frequency = 228), hysteroscopy (frequency = 109), women (frequency = 92), management (frequency = 89), expression (frequency = 80), pregnancy (frequency = 75), ashermans syndrome (frequency = 72), infertility (frequency = 68), prevention (frequency = 55) and fertility (frequency = 52),in Fig. 4B.And in Table 4,the most significant keywords were adhesion (centrality = 0.24), pregnancy (centrality = 0.20), expression (centrality = 0.13), intrauterine adhesionis (centrality = 0.12), women (centrality = 0.10), adhesion molecule (centrality = 0.09), diagnosis (centrality = 0.08), activation(centrality = 0.08), hysteroscopy (centrality = 0.07) and fertility (centrality = 0.07). Then we obtained the largest 6 clusters as shown in Fig. 4C, D and Table 5, and the modularity Q is 0.4518, the weighted mean silhouette S is 0.8038. Summarizing the main research directions of the six clusters, we found that most of them are treatments for intrauterine adhesions. After analyzing the keywords by timeline, it is found that new keywords appear almost every year. As shown in Fig. 5, according to keyword burst analysis,during 2006–2021, there were 23 keywords to be found to have the strongest citation outbreak. It can be observed that before 2014, the research hotspots of intrauterine adhesions mainly focused on the treatment of intrauterine adhesions, infertility and assisted reproductive technology, while in recent years, the hotspots focused on stem cell technology, endometrial repair and regeneration. Moreover, the concept of endometrial repair and regeneration which was proposed in 2018 has the highest citation rate, and is considered as the hottest and newest research direction in this field.
Table 4
The top 10 keywords sorted by centrality.
NO. | Keywords | Centrality |
1 2 3 4 5 6 7 8 9 10 | Adhesion Pregnancy Expression Intrauterine adhesionis Women Adhesion molecule Diagnosis Activation Hysteroscopy Fertility | 0.24 0.20 0.13 0.12 0.10 0.09 0.08 0.08 0.07 0.07 |
Table 5
The analysis of the top 6 clusters.The cluster analysis results mainly include cluster ID, mean year, size, silhouette, label.Size expresses the number of keywords contained in the cluster, and Mean Year expresses the average year of documents in the cluster.
ClusterID | Size | Silhouette | Mean(Citee Year) | Label(LLR) |
0 1 2 3 4 5 | 129 79 75 69 63 22 | 0.817 0.798 0.842 0.731 0.773 0.867 | 2016 2012 2008 2011 2011 2010 | Hysteroscopy Hysteroscopy Placenta Office hysteroscopy Uterus Laparoscopy |