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Research
Kyermang Kyense Dakok
Universiti Sains Malaysia
Corresponding Author
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Background
A blood mimicking fluid (BMF) is made up of a mixture fluid and ultrasound scattering particles that stay neutrally buoyant in the fluid. For these particles to be able to remain suspended in the fluid, their density must be very close or equal to the density of the mixture fluid and the BMF must also have its acoustic properties (speed of sound, attenuation and backscatter power) and physical properties (density and viscosity) close to the internationally acceptable standard. This paper introduces D(+)-Glucose (DG) as an important component of a mixture fluid consisting of Propylene Glycol (PG) and water for preparing a hyperglycemic blood mimicking fluid (BMF).
Methodology
The BMF was prepared by first preparing different samples of ternary mixture fluids in which a fixed amount of PG was mixed with various amounts of water and DG to get a particular and suitable percentage combination that yielded a density similar to that of poly (4-methylstyrene) scatter particles. A required amount of the scatter particles was mixed with the suitable mixture fluid to form a BMF with good physical and acoustic properties accepted by the International Electrochemical Commission.
Results
A very good BMF was produced consisting of 84% distilled water, 5% of PG and 11% of DG as the ternary mixture fluid mixed with 0.8% Poly (4-methylstyrene) scatter particles. It has a density of 1.040 g/cm3, viscosity of 4.30 mpa.s, speed of sound of 1580 m/s and attenuation of 0.017 dB/cm at 5MHz, having a good back scatter property.
Conclusion
DG is a good substance that forms part of the ternary mixture fluid for the preparation of a hyperglycemic BMF with suitable physical and acoustic properties.
Keywords
Propylene Glycol, D(+)-Glucose, Blood Mimicking Fluid, Physical Properties, Acoustic Properties, Ultrasound
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Kyermang Kyense Dakok
Universiti Sains Malaysia
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 15 Jan, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Biomedical Engineering
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
A blood mimicking fluid (BMF) is made up of a mixture fluid and ultrasound scattering particles that stay neutrally buoyant in the fluid. For these particles to be able to remain suspended in the fluid, their density must be very close or equal to the density of the mixture fluid and the BMF must also have its acoustic properties (speed of sound, attenuation and backscatter power) and physical properties (density and viscosity) close to the internationally acceptable standard. This paper introduces D(+)-Glucose (DG) as an important component of a mixture fluid consisting of Propylene Glycol (PG) and water for preparing a hyperglycemic blood mimicking fluid (BMF).
Methodology
The BMF was prepared by first preparing different samples of ternary mixture fluids in which a fixed amount of PG was mixed with various amounts of water and DG to get a particular and suitable percentage combination that yielded a density similar to that of poly (4-methylstyrene) scatter particles. A required amount of the scatter particles was mixed with the suitable mixture fluid to form a BMF with good physical and acoustic properties accepted by the International Electrochemical Commission.
Results
A very good BMF was produced consisting of 84% distilled water, 5% of PG and 11% of DG as the ternary mixture fluid mixed with 0.8% Poly (4-methylstyrene) scatter particles. It has a density of 1.040 g/cm3, viscosity of 4.30 mpa.s, speed of sound of 1580 m/s and attenuation of 0.017 dB/cm at 5MHz, having a good back scatter property.
Conclusion
DG is a good substance that forms part of the ternary mixture fluid for the preparation of a hyperglycemic BMF with suitable physical and acoustic properties.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
The full text of this article is available to read as a PDF.
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