Background: The purpose of this article is to report the treatment outcome of a patient with nasopharyngeal neuroendocrine carcinoma.
Method: The patient received concurrent chemoradiotherapy(CRT) for the primary lesion and microwave ablation for isolated hepatic metastasis later.
Results: Complete remission (CR) was achieved after the completion of concurrent CRT. However, prophylactic cranial irradiation(PCI) was not performed. Isolated hepatic metastasis was diagnosed 3 months after the completion of CRT. Then microwave ablation for isolated hepatic metastasis was performed cc. Finally, unlike the most common death caused by brain metastasis in literature retrieval, the patient died of hepatic function failure caused by multiple hepatic metastasis. The overall survival(OS) of the patient is about 18 months.
Conclusion: Standardized concurrent CRT also has a good therapeutic effect on nasopharyngeal neuroendocrine carcinoma.The administration of prophylactic cranial irradiation may not be necessary for nasopharyngeal neuroendocrine carcinoma,which remains to be conformed.