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Maria Vikentjeva
Tervise Arengu Instituut
Corresponding Author
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BACKGROUND Rickettsia spp. are human pathogens that cause a number of diseases and are transmitted by arthropods, including ixodid ticks. Estonia contributes a region, where the distribution area of two exophilic tick species of known medical importance, Ixodes persulcatus and I. ricinus, overlap. The presence of the nidicolous rodent-associated I. trianguliceps has recently been shown for Estonia. Although there is no Estonian data available on human disease caused by tick-borne Rickettsia spp., the presence of three Rickettsia species in non-nidicolous ticks, albiet at very dissimilar rates, was also previously reported. The aim of this studywas to screen, identify and characterize Rickettsia species in nidicolous and non-nidicolous ticks attached to rodents.
RESULTS Nymphs and larvae of I. ricinus ( n = 1004), I . persulcatus ( n = 75) and I. trianguliceps ( n = 117) attached to rodents and shrews caught in different parts of Estonia were studied for the presence of Rickettsia spp. by nested PCR. Ticks were removed from 314 small animals of 5 species (bank voles Myodes glareolus , yellow necked mice Apodemus flavicollis , striped field mice A. agrarius, pine voles M. subterranius and common shrews S. araneus) . Rickettsial DNA was detected in 8,7% (103/1186) studied ticks. In addition to R. helvetica, previously found in questing ticks, this study reports the first identification of the recently described I. trianguliceps- associated Candidatus R. uralica in west of the Ural.
Keywords
Ticks, Rickettsia spp., Candidatus Rickettsia uralica, voles, mice
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CURRENT STATUS: Published
View the published article at Parasites & Vectors.
No community comments so far
Editorial decision: Accept
On 25 Dec, 2020
Editor invited
On 22 Dec, 2020
Editor assigned
On 22 Dec, 2020
Submission checks complete
On 22 Dec, 2020
No comments provided
Editorial decision: Major Revision
On 21 Nov, 2020
Review #1 received
Received 27 Apr, 2020
Review #2 received
Received 27 Apr, 2020
Reviewer #2 agreed
On 20 Apr, 2020
Reviewers invited
Invitations sent on 16 Apr, 2020
Reviewer #1 agreed
On 16 Apr, 2020
Editor assigned
On 25 Mar, 2020
Submission checks complete
On 24 Mar, 2020
Editor invited
On 24 Mar, 2020
No comments provided
Editorial decision: Revise before peer review
On 09 Mar, 2020
Editor assigned
On 28 Feb, 2020
Submission checks complete
On 27 Feb, 2020
Editor invited
On 27 Feb, 2020
Version 1
Posted 19 Feb, 2020
No comments provided
Editorial decision: Revise before peer review
On 22 Feb, 2020
Editor invited
On 18 Feb, 2020
Editor assigned
On 18 Feb, 2020
First submitted
On 17 Feb, 2020
Submission checks complete
On 17 Feb, 2020
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Subject Areas
Parasitology
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A new preprint design is coming!
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See the published version of this preprint at Parasites & Vectors.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Maria Vikentjeva
Tervise Arengu Instituut
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Parasites & Vectors.
No community comments so far
Editorial decision: Accept
On 25 Dec, 2020
Editor invited
On 22 Dec, 2020
Editor assigned
On 22 Dec, 2020
Submission checks complete
On 22 Dec, 2020
No comments provided
Editorial decision: Major Revision
On 21 Nov, 2020
Review #1 received
Received 27 Apr, 2020
Review #2 received
Received 27 Apr, 2020
Reviewer #2 agreed
On 20 Apr, 2020
Reviewers invited
Invitations sent on 16 Apr, 2020
Reviewer #1 agreed
On 16 Apr, 2020
Editor assigned
On 25 Mar, 2020
Submission checks complete
On 24 Mar, 2020
Editor invited
On 24 Mar, 2020
No comments provided
Editorial decision: Revise before peer review
On 09 Mar, 2020
Editor assigned
On 28 Feb, 2020
Submission checks complete
On 27 Feb, 2020
Editor invited
On 27 Feb, 2020
Version 1
Posted 19 Feb, 2020
No comments provided
Editorial decision: Revise before peer review
On 22 Feb, 2020
Editor invited
On 18 Feb, 2020
Editor assigned
On 18 Feb, 2020
First submitted
On 17 Feb, 2020
Submission checks complete
On 17 Feb, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Parasitology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Parasites & Vectors.
BACKGROUND Rickettsia spp. are human pathogens that cause a number of diseases and are transmitted by arthropods, including ixodid ticks. Estonia contributes a region, where the distribution area of two exophilic tick species of known medical importance, Ixodes persulcatus and I. ricinus, overlap. The presence of the nidicolous rodent-associated I. trianguliceps has recently been shown for Estonia. Although there is no Estonian data available on human disease caused by tick-borne Rickettsia spp., the presence of three Rickettsia species in non-nidicolous ticks, albiet at very dissimilar rates, was also previously reported. The aim of this studywas to screen, identify and characterize Rickettsia species in nidicolous and non-nidicolous ticks attached to rodents.
RESULTS Nymphs and larvae of I. ricinus ( n = 1004), I . persulcatus ( n = 75) and I. trianguliceps ( n = 117) attached to rodents and shrews caught in different parts of Estonia were studied for the presence of Rickettsia spp. by nested PCR. Ticks were removed from 314 small animals of 5 species (bank voles Myodes glareolus , yellow necked mice Apodemus flavicollis , striped field mice A. agrarius, pine voles M. subterranius and common shrews S. araneus) . Rickettsial DNA was detected in 8,7% (103/1186) studied ticks. In addition to R. helvetica, previously found in questing ticks, this study reports the first identification of the recently described I. trianguliceps- associated Candidatus R. uralica in west of the Ural.
This is a list of supplementary files associated with this preprint. Click to download.
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