The patient, male, 73 years old, was admitted to our department on March 17, 2021 due to an acute unexplained weakness of limbs. He has a history of hepatitis B, schistosomiasis and liver cirrhosis, and has no addiction to tobacco and alcohol. Eventually, we found that his weakness was related to hypokalemia caused by hyperhidrosis. After supplementing potassium, his motor function returned to normal. He was discharged from our hospital on March 23. On that day, the patient supplemented his medical history in detail. He is usually introverted and timid. The COVID-19 pandemic in early 2020 lead to his anxiety and insomnia for more than a year. He slept for 2-3 hours a day. After taking estazolam, he could sleep for 4-5 hours. And then, his appetite increased significantly half a year ago. He ate a lot every meal, ate more than ten meals every day, and didn’t stop eating until he felt uncomfortably full. He had never felt ashamed or thought of weight control. At the same time, many other symptoms were accompanied including dry mouth, bitter mouth, chest tightness, hyperhidrosis, severe abdominal distension, constipation. Only could an enema improve his defecation and the extreme discomfort of abdominal distension. He was diagnosed with BED and had tried a variety of treatments including psychotherapy and pharmacotherapy. However, the treatments had no effect, so he was transferred to dozens of hospitals because of these painful symptoms above and he felt desperate. He was 171cm high, 80kg weight (70kg half a year ago) and normal in nervous system examination. However, he had slightly dark tongue, tooth marks on the sides of his tongue, tortuous and swelling sublingual veins, yellow and slippery tougue coating. His pulse was deep and weak. On March 18,2021, he was normal in blood routine, thyroid function, liver and kidney function, fasting blood glucose, glycosylated hemoglobin. There were some abnormal data below, including low blood potassium 2.3mmol/l, high triglyceride (TG) 3.99mmol/l, high LDL-L2.49mmol/ l, high D-2 polymer 2.93mg/l, high fibrin degradation product 6.72mg/l, low antithrombin 3 activity 60.6%. His Hepatitis B surface antigen was positive. His head MRI was normal. His Beck Depression Inventory has 18 points, the Beck Anxiety Inventory has 26 points, and the neuropsychiatric questionnaire (NPI) has 6 points for anxiety scale, 12 points for sleep scale, and 12 points for eating disorders scale. Before he was discharged from the hospital, his blood potassium was 3.87mmol/l (-). At last, the patient was diagnosed with BED according to the DSM-5. Because his BED episodes were more than 13 per week, the level of severity was estimated as extremely severe. His TCM diagnosis was frequent eating, and the syndrome type was that liver Qi depression, spleen Qi deficiency, and mixture together with phlegm, blood stasis and heat. Based on his TCM syndrome type, the herbal formula was as follows: Bupleuri Radix 15g, Fructus Aurantii 15g, Magnolia Officinalis Cotex 15g, Gypsum 30g, Anemarrhena 15g, Chinese Yam 30g, Roasted Licorice 10g, Cinnamon Twig 10g, Leech 10g, Ground Beetle 10g, Peach Seed 10g, Codonopsis 15g, Poria 15g, Pinellia Ternata 15g, Tangerine Peel 15g, Whole Melon 30g, Cistanche 15g, Keel 15g, Oyster 15g, Rhubarb 10g (additional package). The formula was mixed together, boiled for 30 minutes and got 400ml liquid. The patient took 200ml solution once and twice a day, in all 14 days. On April 6, 2021, he returned to my clinic. His constipation was disappeared. His other discomfort, including abdominal distension, hyperhidrosis, dry mouth, bitter mouth and chest tightness, improved significantly. His tongue returned to rosy and his coating returned to thin and white. The number of meals was reduced to 7-8 meals a day. This time, Raw Rhubarb was removed from his last formula because his bowel movement was smooth and continued to take the herbal medication for 30 days. His third visit was on May 6, 2021. At that time, he ate 5-6 meals a day. His abdominal distension was completely disappeared. His symptoms, such as sweating, dry mouth and bitter mouth, were markedly improved. So, Fructus Aurantii and Magnoliae Officinalis Cortex were removed from the second recipe. The recipe was prescribed for 30 days. His fifth visit was on June 5, 2021. At the time, he ate 3-4 meals a day. Each meal had a normal amount of food. Hyperhidrosis, dry mouth, bitter mouth, and bad breath were disappeared, and his weight dropped to 75kg. The tongue almost returned to normal, and the tortuosity degree of the sublingual veins was improved. Blood coagulation and blood lipids returned to normal, and blood routine, liver and kidney functions were normal. His Beck Depression Inventory has 8 points, the Beck Anxiety Inventory has 8 points, and the neuropsychiatric questionnaire (NPI) has 2 points for anxiety scale, 3 points for sleep scale, and 1 points for eating disorders scale. So, Pinellia Ternata, Tangerine Peel, Keel, and Oyster were removed. It was recommended for the patient to take the herbal formula for another two months to consolidate the treatment effect. During the whole period of TCM treatment, besides taking Chinese medicine granules and estazolam regularly, he did not receive any other treatment. August 10, 2021, the patient returned to our clinic and said he couldn’t stop the herbal formula, which led to the recurrence of BED and abnormal mood. Therefore, the patient has been taking the herbal formula until now and hasn’t reported any discomforts for 6 months. He no longer despaired, was very satisfied with TCM treatment and was pleased to continuously take TCM herbal formula.