Ethics approval and consent to participate
The study was conducted in accordance with the study protocol, the Declaration of Helsinki and applicable regulatory requirements. We applied for approval of the protocol by the local Institutional Review Board and Ethics Committee of the Ziekenhuis Netwerk Antwerpen, ZNA Stuivenberg approved the protocol (EC approval number: 3001 with insurance policy Ethias 45.313.314) and Ziekenhuis Oost-Limburg, Genk, Belgium (EC 12/084U). Oral and written informed consent was obtained from the relatives of all patients. There were no deviations from standard care.
Consent for publication
Consent for publication of figures and manuscript was obtained from the persons involved.
Availability of data and materials
The datasets used and/or analyzed during the current study are available from the first author on reasonable request.
MLNGM is a member of the medical advisory Board of Pulsion Medical Systems (now fully integrated in Getinge, Solna, Sweden), Baxter and Serenno Medical (Tel Aviv, Israel), and consults for Maltron, ConvaTec, BD, Spiegelberg and Holtech Medical.
All other authors declare that they have no competing interests in relation to the content published in this manuscript.
ASS created the study protocol, performed the measurements, analysed the data, searched for relevant literature and wrote the manuscript.
AH performed the measurements, analysed the data and searched for relevant literature
SC revised the manuscript
NVR edited and revised the manuscript
WG created the study protocol and revised the manuscript
MLNGM created the study protocol, performed the measurements, searched for relevant literature, analysed the data, and revised the manuscript
This work is part of a PhD-thesis, which is supported by the Limburg Clinical Research Program (LCRP) UHasselt-ZOL-Jessa, supported by the foundation Limburg Sterk Merk, Hasselt University, Ziekenhuis Oost-Limburg and Jessa Hospital.
The authors want to thank Robert Wise, Sharona Vonck, Inneke de Laet, Karen Schoonheydt, Hilde Dits, Salar Tayebi, and Wojciech Dabrowski for their help and advice performing the study and editing and revising this manuscript. Manu Malbrain is professor at the Medical University of Lublin and member of the Executive Committee of the Abdominal Compartment Society, formerly known as the World Society of Abdominal Compartment Syndrome (https://www.wsacs.org/). He is co-founder, past-president and current treasurer of WSACS. He is co-founder of the International Fluid Academy (IFA). The mission statement of the IFA is to foster education, promote research on fluid management and hemodynamic monitoring, and thereby improve survival of critically ill by bringing together physicians, nurses, and others from throughout the world and from a variety of clinical disciplines. The IFA is integrated within the not-for-profit charitable organization iMERiT, International Medical Education and Research Initiative, under Belgian law. The content of the IFA website (http://www.fluidacademy.org) is based on the philosophy of FOAM (Free Open Access Medical education – #FOAMed).