How is Dignity Understood and Preserved in Patients with Palliative Needs in the Middle East? An Integrative Review

Background: Patients with palliative needs experience high psychological and symptom distress that may lead to hopelessness and impaired sense of dignity. Maintaining patient dignity or the quality of being valued is a core aim in palliative care. The notion of dignity is often explained by functionality, symptom relief and autonomy in decision making. However, this understanding and its implications in Middle Eastern countries is not clear. The aim of this review is to 1) explore the understanding of dignity and how dignity is preserved in adult patients with palliative care needs in the Middle East 2) critically assess the ndings against the Dignity Model dominant in western literature. Method: Using an integrative review we searched four databases EMBASE, Psych-Info, CINAHL, and PubMed. These databases retrieve a broad literature on palliative care and are often chosen in other palliative care reviews. To enhance the search strategy, three online journals were hand searched, reference lists of review papers scanned, and forward citations sought. No time limits were applied. The retrieved papers were assessed independently by two authors including quality assessment using the Hawker’s appraisal tool. Results: Out of the 5113 studies retrieved, 294 full texts were assessed. Sixteen studies were included for synthesis of which fourteen were published in Iran. Seven themes were developed after data analysis: Maintaining Privacy and Secrecy; Gentle communication with a dialogue that preserves hope instead of blunt truth-telling; Abundance characterised by accessibility to medical supplies and nancial stability; Family Support where relatives deliver major assistance in care; Physical Fitness; Reliable health care, and Social justice that endorses equal care to all. Conclusion: The results are compatible with the existing evidence from the Dignity Model ascertaining that dignity is socially mediated and inuenced by interactions and physical tness. Nevertheless, the ndings highlight that patient dignity is also shaped by the socio-political, cultural, and economic conditions of the country, where family support, gentle communication and accessible health care are essential elements.


Introduction
Patients with advanced chronic or terminal illnesses experience high psychological and symptom distress that may lead to hopelessness and sometimes an impaired sense of dignity (1). Maintaining the dignity of patients who are stressed by the various demands and changes that chronic and advanced illnesses impose on their daily lives is a core aspect of palliative care philosophy (2,3). The purpose of this systematic review was to explore and synthesise the research evidence on the understanding of dignity of patients with chronic and life-threatening illnesses in the Middle Eastern context. An empirical model of dignity developed by Chochinov, constructed by interviewing end stage cancer patients in Canada, (4) described dignity at end of life in three broad categories of 'illness-related concerns', 'dignity conserving repertoire'; and 'social dignity inventory'. This model has been instrumental in developing dignity preserving interventions for patients and families (5). Parallel to the Chochinov ndings, dignity of patients with palliative care needs has been related to functionality, symptom relief and autonomy over the dying process (6, 7). However, this understanding and its implications in Middle Eastern countries that is characterised a religious and family-oriented culture and often affected by political turmoil, is not clear.
Palliative care resources are scarce in Arab-Muslim populated countries in the Middle East (8). The availability and access to opioids to alleviate the pain of patients with terminal or advanced illnesses is restricted through local legislation (9). The integration of palliative care in the national health plan and its acknowledgment as a separate discipline is limited rendering palliative care services fragmented and funding scarce (10). Palliative care education is not fully incorporated into medical and nursing educational curricula leading to a shortage of well-trained palliative care specialists (9)(10)(11), and consequently limiting the access to quality palliative care. The absence of national laws regulating advance decision such as "do not resuscitate" orders and the inconsistent de nition of brain death in Muslim countries presents a hindrance to the development and provision of palliative care, advanced care planning and consequently protecting patient dignity (11). Often the unstable geopolitical, economic, and the mosaic sociocultural fabric of the region that is under a strong in uence of religion, traditions, and culture, shapes the understanding of human dignity in general and subsequently in palliative care settings which then affects policy development and dignity of patients (12,13).
Since family role and religion are recurrent values that envelope the middle eastern individual and has overarching implications in preserving patient dignity (14), it is intriguing to delve into the embedded facets of patient dignity to identify its nuances in the Middle East region in comparison to other regions and cultures and particularly to the dominant Western understanding. Upholding patient dignity is a core ethical value in nursing (15) as well as medical practice (16). Thus, an explicit clarity of this sensitive phenomenon would inform health care providers and educators to attend to and protect the dignity related needs of palliative care patients with cultural humility. No published systematic review has been found in the Middle Eastern context that addresses the concept of dignity in patients with palliative care needs. Therefore, this review is unique, it unfolds pertinent knowledge for all health stakeholders, and paves the way for better clinical practice and future research.

The review question and aim
What is the understanding of dignity and how is dignity preserved in patients with palliative care needs in the Middle East?
The overarching aim of this review is to explore and critically synthesize the evidence on the concept of personal dignity in the Middle Eastern palliative care setting from the perspective of the patient, health care provider, and family caregiver, examining how dignity is enhanced or undermined while receiving care. This review looks at: 1. The perceptions of the concept of human dignity from the perspective of the patient, family caregiver, or health care provider within adult palliative care in the Middle Eastern region.
2. Behaviours or aspects of care that enhance or undermine the sense of dignity in patients with palliative care needs during illness experience and while receiving health services.
3. Critically assess the ndings against the Dignity Model dominant in the western literature.

Review Method
An integrative method was adopted for this review (17). An integrative review combines studies with diverse methodologies bringing forward a better understanding of complex phenomena. The inclusiveness of various research designs facilitates the building of comprehensive evidence that can be used to guide clinical practice and health policy. This openness to diverse methodologies allows the clear de nition of concepts, appraisal of the existing evidence, and identi cation of knowledge gaps (17). To enhance the rigor, a systematic and explicit methodology is applied throughout the review process, informed by the guideline set by Whittemore and Kna (17)  The SPICE (Setting, Perspective, Intervention/ Phenomenon of Interest, Comparison, Evaluation) framework, that is appropriate for explorative questions, is applied to dissect the research question into elements, expand search terms, and specify study eligibility criteria for inclusion (18). The SPICE elements of "perspective", "comparison" and the "outcome/ evaluation" are not included in the search strategy to broaden the scope and optimize sensitivity (19). Elements of the SPICE as employed in the research question are elaborated in Table 1 below. De nition of key terms: Dignity-"the quality or state of being worthy, honoured, or esteemed" (20).
"Patient with palliative care needs"-is the individual suffering from a life-threatening condition that holds no possibilities of remission or cure. This encompasses patients suffering from a diverse incurable or progressive long-term illnesses such as cancer, organ failure, or degenerative diseases, who require physical, psychosocial, and spiritual care (21).  (23) and are often chosen in other palliative care reviews (7). Keywords, medical subject headings (MeSH) and multiple synonyms such as, "dignity", "respect", "self-concept", "selfesteem", "palliative care", "terminally ill patients", "life-threatening", "end of life", "dying", "Arab", "Muslim", and "Mediterranean" were used simultaneously to search the titles and abstracts of captured papers. See Table 2. (MM "Culture") OR (MM "Cultural Diversity") OR (MM "Middle East") OR (MM "Islam") OR (MM "Arabs") The systematic search was conducted in December 2019 and the nal search updated in December 2020. No date limits were set. The search strategy was modi ed on each database to adapt to its subject index or thesaurus terms (24). The controlled vocabulary and free terms of each concept are combined in the search using the Boolean operator "OR". Once each concept was combed, the searches were united with the Boolean operator "AND" to distil the nal number of papers intersecting the three concepts. Supplemental methods of screening were employed to enhance the sensitivity of the search such as scanning the reference lists of review papers and included manuscripts, forward citation tracking, and hand searching of key journals (18).
The online journals, 1) Nursing Ethics, 2) The Medical Journal of Ethics & 3) Journal of Medical Ethics and History of Medicine, that publish relevant papers on dignity were screened for the last ten years. The retrieved manuscripts were vetted against the inclusion/exclusion criteria elucidated in Table 3. Many mental health patients suffer from marginalization and injustice implying a broader action on dignity than that of palliative patients (27).

Inclusion-Exclusion Criteria
Children within palliative care have unique dignity needs that differ from adults (28).  (29).
Empirical studies are deemed appropriate to provide evidence on perceptions, in uencing factors, or outcomes of dignity.
Due to restricted resources, papers are limited to English language.

Evaluation/ Outcomes
The outcome of enhanced or impaired dignity as well as perceived bene ts or threats will be examined.
Studies that have dignity as a secondary outcome will also be included.

Outcomes other than dignity
Search Outcomes And Data Extraction

Search Outcomes & Data Extraction
The search identi ed 5007 records from the four health databases that were transferred to an EndnoteX8 bibliography software for storing and removing duplicates. Seventy-three additional relevant papers were identi ed from the three journals and thirty-three from reference lists of review and included papers. After eliminating duplicates (n=2625), 2488 papers were screened independently by two researchers (S.D.S.) and (R.S) by title and abstract against the inclusion criteria. The papers (n=2194) that did not meet inclusion criteria were excluded. The potentially relevant papers (n= 294) were led in Endnote for full manuscript review. These papers were categorised as those related to papers on patients' needs, 'good death' papers, review papers, pure dignity papers, and so forth. A further 266 papers were excluded because many were not related to perceptions of dignity. Finally, the publications were narrowed to twenty-eight potentially relevant papers for a full script reading. In line with the Whittemore and Kna (17) guidance, the data from the twentyeight papers were reduced and displayed in an excel sheet in the form of a table. The table delineated the main characteristics of each paper such as the author, date of publication, country of origin, discipline, study design, aim, participants, context, sample size, data collection, data analysis, and ndings. In the nding's column, actual quotations from the primary papers were incorporated to preserve their wholeness. The tabular display allowed the visualization and the iterative studying of the papers to identify their unique characteristics. A second reviewer independently extracted the data from 50% of the included papers (R.S.) to validate the process and relevance of the records. After discussion and consensus with the wider team (NP, YS and RS), 16 dignity papers were included for nal synthesis. The PRISMA chart in Figure 1 displays the process.

Data Evaluation
The quality of the included sixteen papers were evaluated using the Hawker appraisal tool (30) that has broad criteria appropriate for appraising research from different paradigms and commonly used in palliative care reviews (31,32). Though the papers were evaluated and scored, no manuscript was excluded for its weak score. Instead, the impact of each paper was reported with a critical assessment in the synthesis (33).

Data Analysis
The data analysis stage involved categorizing, coding, and summarizing, of the included 16 papers to facilitate the organisation and reduction of the literature in a frame. The reports were primarily grouped according to their research design, and those that discussed perceptions of dignity, facilitators, barriers, or health outcomes of dignity. Codes were developed, such as "personal values of dignity", "health care related issues", "communication at end of life", from each paper and arranged in a matrix to allow clear visualisation and comparison of patterns or variations. The codes were collated so that similar ones, such as the cleanliness of the hospital rooms, private space, quick service, and noise in the units, were assembled to generate a common theme, for instance, health facilities. Non-conforming codes were interrogated to unpick underlying social values like excessive treatment, distress in female patients, or retaining hope in the face of grave health condition. The analysis was an iterative process involving merging of codes and creating themes and subthemes to achieve a higher level of interpretation and abstraction (Table 6). Seven interrelated themes were developed that incorporated most of the codes. The conclusion was synthesized by integrating the themes and building a logical chain of how dignity is understood, enhanced or threatened that developed an original knowledge of dignity beyond surface description (17). one paper adopted phenomenology (34), one critical ethnography (35) and one thematic analysis identifying a thematic framework (36). Whereas the quantitative studies were all descriptive, or descriptivecorrelational in nature. See Table 4 for a summary of the characteristics of the 16 papers.

Country of Publication
Fourteen studies were published in Iran only one from Turkey (Korhan et al    Themes The seven themes, as generated from the analysis, related to the understanding of patient dignity in illness and while receiving care is described here. A. Maintaining Privacy & Secrecy: Paying attention to patients' privacy during care and being considerate of keeping personal information con dential was seen as respecting patients' sense of dignity. Patients and health care providers agree that having a personal space like a private room in the hospital with separation curtains, personal toilet, a decent hospital gown that does not expose body parts, is considered essential to preserving patient dignity (34,(36)(37)(38)(39). Crowded spaces and proximity to other patients that prevent performing basic self-care activities comfortably such as using the bedpan or washing diminish dignity. Entering patient rooms without prior knocking, particularly when female patients did not have their head veils in place (39), or loudly announcing frequency of defecation, offended patient privacy (35). Unannounced nursing or physician ward rounds were regarded as disrespectful and gave way to indecent body exposure to patients not only in a palliative context but also in any clinical setting irrespective of specialty (40,41). Questions from the nursing staff that probed into the patient's personal life such as how the illness had impacted intimacy was regarded to be unethical, rude, and infringing on patient's privacy (38). Recurrent interactions with health care providers and hospitalisations increased patient vulnerability and the risk of losing personal and physical privacy that threatened dignity (42)(43)(44). This could be related to the imperfect health care system and increased vulnerability of the patients.
Maintaining con dentiality of the medical diagnosis and limiting disclosure to a restricted family member is regarded of the utmost importance to patients (39,45), to the extent that some individuals would deliberately search hospitals that are far from their residencies to maintain discretion (38). Informing others about their illness carried the risk of stigmatisation or social isolation that risked losing societal status. This was true for patients with chronic non-cancer and cancer conditions. For instance, revealing the diagnosis of cancer or multiple sclerosis placed the patient at risk of being judged or looked down upon by the community, and missing out chances of getting married for both men and women (38,46) which were key elements to maintain dignity. Secrecy regarding lifestyle or certain practices, such as the use of opium in male patients, was crucial to maintain a sense personal dignity (39).
B. Gentle Communication: too much pity, blaming, or bluntly disclosing bad news is regarded disrespectful and damaging to personal pride and dignity. Paying attention to patient values, empathising, and delivering what he/ she is ready to hear is considered compassionate and enhancing of dignity (36-39, 45, 47).
Expressions of pity are regarded to be patronising to the patient by a rming the patient's weak position. Patients valued communicating hope and considered it superior to truth-telling, even in conditions of poor prognosis (34,36). Blunt disclosure of diagnosis is undesirable by the patients and health care providers with the belief that maintaining a glimpse of hope promotes patient dignity (34,38). Abstaining from talking about the seriousness of the condition and believing in the person's predestined fate, surrendering to God's will, is a coping mechanism to maintain dignity (36). Despite the nondisclosure of the diagnosis, nurses kept informing patients about the inevitable adverse effects of cancer medications like hair loss (47) indicating that patients often were inherently aware of their condition, upholding a glimpse of truthfulness . Amid hospitalization and illness, patients were keen on following their religious rituals such as prayers to preserve their identity and dignity (36). For instance, a patient was upset to have missed morning prayer due to receiving a sleeping pill the night before (39,45). On the organisational level, bureaucracy, strict regulations (48), and communication that is not driven by patient needs, but is rather paternalistic or routine-oriented, reduces patients' experiences of being valued (35). For instance, strict visiting hours, excluding family members, banning the use of telephones, restricting patient freedom undermine the sense of worth and trust among patient and health care provider, consequently diminishing overall satisfaction with care and sense of dignity (37,39,45). Attentive communication that is engaging, and mindful of individual preferences assures a digni ed experience (39). Though communication implies that dignity is a dynamic relational process mediated by social interactions and environmental factors, it is also an individual perception affected by how one views self-worth and communicates internally with self. For instance, self-blame, selfdoubt and the belief that the illness is the result of personal de ciencies is harmful; whereas focusing on personal strengths and opportunities promotes dignity (46). Perceptions of self-value are in uenced by the individual's understanding of their purpose in life, relationships to others, religious beliefs, and cultural norms. Faith is either an impetus for expression of resilience or a predisposition to succumb under the pressure of ill health and see its limitations as an unjusti ed loss that is to be born (46).
C. Abundance of resources: Economic burdens and overshadowing fears of not getting hold of the essential medical resources and health services due to unavailability or inaccessibility are damaging to personal identity and dignity (38,43,44,49). Recurrent admissions to the hospital are associated with high expenses, nancial burdens, increased reliance on family support, and heightened patient vulnerability (42)(43)(44). In contrast, economic prosperity is related to perceptions of being worthwhile, digni ed, having a purposeful life, and a meaningful social role (49). Patients with or without palliative needs valued the availability of su cient medical resources and spacious facilities in the health care system, such as clean and separate lavatories, good lighting, and silence in the intensive care units (40,45,50). Unequal or disparate care is practiced in times of shortage of resources, medical staff, especially nurses, who become overworked and unable to meet the entire patients' needs (45). Multiple sclerosis patients who could earn an income despite their disabilities felt more digni ed and useful compared to those who were forced to resign (46). In this regard, education and competencies, such as pro ciency of languages, problem-solving skills, were protective to patients' dignity because, amidst physical disability, it secured employment (46). The inability to sustain economic steadiness is particularly frustrating to the young patients because idleness rea rmed a sense of un tness closing down on chances of achieving life goals, hence, shattering personal dignity through the inability to provide for oneself (43,46). D. Family Support: family caregivers are regarded as a central block of support system to the patient, particularly during hospitalisation for women (44,45,49). The patient anticipates family caregivers to be present, and be included in care planning, and discharge preparations (38,39,45). Patients who were living alone or lacked a support system from friends and family had a higher sense of disease burden than those who were married or who enjoyed family support (42,46). The family offered a social security net, particularly for women, for whom maintaining a social role for instance of a "mother who cooks for the family" was an a rmation to self-esteem and personal dignity (36). The role of the family caregiver extends beyond the acute hospital setting to offering care and assistance after discharge (36). The family members helped patients adhere to treatment and lifestyle regimens, nd symptom relief, and seek medical help when needed (45,52). For this reason, effective communication between health care providers and patient/family, that entails conveying explanations about the disease and its management, is regarded as crucial to empower the ill individual in making informed decisions and achieving improved outcomes thereby maintaining dignity (34,39,(45)(46)(47). Patients with chronic conditions desire the social environment to be responsive, engaged and understanding to their social needs to uphold independence, security, and wellbeing. A supportive community that empowers patients by offering accessible self-care facilities (39), comfortable housing, safe transportation means, economic stability, is regarded as digni ed standards of living and much desired (45,46). E. Physical Fitness: It is worth noting that functionality and low symptom burden foster patient dignity within the family context (44,53,54). The capability to independently perform daily self-care practices (43), being physically in control of the body, are seen to promote self-concept acting as a protective agent to dignity (37,42,46,49,53,54). A correlational study by Hosseini, Rezaei (53) reported that higher physical functionality was associated with lower anxiety, enhanced sense of worth, better symptom control, autonomy, and overall better quality of life in end-stage cancer patients. Whereas reduced physicality diminished privacy, and changes in appearance brought forward feelings of loss of dignity and being a burden on friends and family (42,44,54). Distressing physical symptoms and uncertainty of the health condition seem to be detrimental to mental wellbeing too, leading to excessive worrying, anxiety, and depression due to the inability to cope with the heightened sense of loss of control (42,43,49,53). Thus, focus on psychological and physical symptom management is highly perceived to maintain dignity in patients with palliative needs (34).
F. Reliable Health Care: Expert medical staff with specialized knowledge and prompt attention to patients' needs are regarded as essential to digni ed health care irrespective of the clinical setting or patient diagnosis (38,39,45,55). Competent hospital staff members who are diligent, kind and attend to patient needs, despite the unfavourable conditions of the health care institution (high workload or shortage of sta ng and resources) are appreciated by all patients (37,39,41,45,55). Time given to assess and talk to patients and not only medicate is vital in the understanding of digni ed care (34,47,56). Whereas a reductionist order that objecti es human encounters to medical tasks and body organs instead of a holistic approach fails to protect patient uniqueness and personal dignity (35). Safe and error-free services transmit a sense of security and assurance that no harm is incurred to the patient's wellbeing (39,45). A su ciently staffed ward that is run by health care providers who appear clean with proper simple attire, was seen to provide an effective and respectful communication that in turn, promotes patient dignity (37,45). Gendersensitive care in the hospital is essential to female patients (38) as well as preferred in male patients to enable a digni ed self-concept particularly when it is related to personal care (39). While for patients who were at end of life, maintaining their physical needs till the last minute of life such as continuing arti cial feeding, body hygiene, and pain management, were regarded highly essential in maintaining the dignity of the dying patient by nurses and patients with heart disease (34,45,47). Though blindly following cureoriented care was sometimes seen as controversial by health care providers and caused personal dilemma (34).
G. Social justice: Patients expect to have just and equal care regardless of low social or economic rank. Being left behind, stigmatized or marginalized due to hardship, foreign nationality, or a medical condition such as addiction or contagious infection, does not foster personal dignity (37). Though health care providers hold a rm conviction and oath of providing equal health care to all (34), there existed a gap between the values and actions of health care providers' where services delivered are affected by consumers' status (35). A sense of injustice was reported in Shari , Borhani (46) when patients with multiple sclerosis, hoped and aspired to have equal opportunities for work, family life, marriage, and non-discriminatory mindset in society that could maintain personal identity and dignity. Humility, mutual trust, compassion, and the gratitude that springs from this altruistic human relationship are sought by patients that is perceived as transcendental dignity (39,55).
Being a female patient with palliative needs increases the emotional distress and instances of decreased dignity (42). Wives with physical disabilities or weaknesses felt their husbands did not perceive them as complete partners due to their ailment. Some women suffered from disrespect, marital discordance, and had lost intimacy in their relationship (46). Women often lost their peace of mind for maintaining their role as a wife or a mother in the family household (49). Men, on the other hand, felt useless when they lost their jobs or were rejected for employment due to their health condition (46).

Discussion
The purpose of this review was to integrate and critically synthesise the knowledge on dignity of patients with palliative care needs and how it is in uenced during illness and as a health care consumer in the middle east. Dignity is threatened in illness, in both genders, maybe sometimes more in females, when individuals lose the ability to assert their traditional roles in the family or community (38,39,46). Insu cient symptom relief, loss of functionality, and the uncertainty of outcomes (43,49,53) aggravate the sense of loss of social role. A patient's personhood thrives within the protected boundaries of privacy, con dentiality, and preservation of sociocultural formalities that nurture a sense of security (34,(37)(38)(39)45).
When consuming health services, personal dignity is fostered by the empathetic and compassionate interaction between the patient and the health care provider. The patient and family expect information about self-care practices delivered in a sensitive way respecting individual values and cultural preferences.
Objectifying attitudes, non-engaging, or non-symmetrical communication between patients and health providers are perceived as disrespectful and a major opponent to digni ed health care (35).
Comparing these ndings against the Chochinov's empirical Model of Dignity (4), shows overall compatibility to its three domains in that the phenomenon of dignity is affected by illness concerns, shaped by personal outlook and resilience, as well as mediated by social relationships. Loss of physical or cognitive tness appears to disturb patient dignity irrespective of geographical or cultural setting. Preserving social role and support seeking spiritual comfort and the capacity for independent body care maintained the pride and dignity of patients. The more the invasion of personal body space by caregivers and the open "uncivilized" discussion of body products such as the number of bowel movements, the more the disruption of privacy and thus personal dignity. Moreover, new themes like economic stability, availability of resources, reliance on religious faith, upholding hope for improved health, and the central partnering role of family members in the care of the patient emerged as distinct nuances in the understanding and preservation of patients with serious illnesses. These themes re ect underpinning socioeconomic aspects and cultural values that shape the perception of dignity in illness in middle eastern culture. Self-determination and an individual's need to control life and death events that is congruent to the dignity attributes in the western societies (6), is overshadowed with the collective decision making and the prayerful commitment to surrender to God's sovereignty in controlling the illness and life destiny. In sickness, hope for a divine miracle of recovery or any improvement in health takes precedence to medical management. Gentle disclosure of the prognosis maintains aspiration for better health by patients even in futile conditions (34,38,47). Telling the truth about the diagnosis and prognosis, though considered the reasonable practice in the Western cultures to promote patient wishes (57), is considered rude in the eastern Mediterranean region. The unique themes emerging from this review are displayed in a preliminary model of Dignity in Figure 2.
It is worth commenting that the phenomenon of dignity is not equally explored in all countries of the region and it represents predominantly an Iranian lens that has a majority Muslim-Shia population (58). The Iranian health care system has been under signi cant funding constraints due to the strict economic sanctions (59).
This implies that poor political and economic conditions and scarcity of medical supplies deprive patients from attaining full health, leaving them feeling worthless and undigni ed (35,38,46,60). Nevertheless, the ndings may also be valid in other Middle Eastern countries where the health care sector is strained due to economic crisis, such as Lebanon, leading to disparities and unequal distribution of health care (61).
Most of the included qualitative studies in this synthesis adopted qualitative content analysis as a tool for data analysis. Content analysis mostly nds meaning through the recurring codes with the application of various levels of interpretations of manifest or latent concepts. It was unclear whether content analysis adopted in the research papers, is applied as a methodology or as a tool in the studies. Hence, the underpinning philosophical assumptions of the researcher, when explicitly stated in the manuscript, would re ect a better understanding of data analysis and ndings (62,63).

Strengths and Limitations
The strength of integrative reviews is that it allows a comprehensive grasp of a complex phenomenon by combining both quantitative and qualitative research studies. However, analysing the data and collating themes from diverse sources can be challenging (17). All the pertinent studies were included regardless of their quality. Due to restraints in resources, only English language papers were included, excluding evidence reported in other languages. Most of the quantitative evidence is descriptive or correlational reporting the level of perceived dignity and identifying various factors, social and illness related, that affect personal dignity. On the other hand, qualitative papers uncover the personal understandings of the dignity phenomenon without the application of predetermined tools. The synthesis clari es the meaning of dignity in patients with palliative needs by identifying common themes and tapping on subtle differences that are relevant to culturally competent health care practice and policy.