A 54-year-old male patient presented to the department of neurology with a state of confusion and balance disorders, he has a history of insulin-dependent diabetes and high blood pressure. Five months earlier, the patient suffered from painless bilateral red eyes with decreased visual acuity. Over the course of the last three months, he started developping memory disorders, hearing impairment, dizziness, and experiencing moderate headaches, unexplained crying and visual hallucinations. There was no reported fever, seizures or vomiting. On physical exam, the patient was confused, but had normal vital signs values. Neurological exam revealed cerebellum ataxia with dysmetria and intention tremors, associated to bilateral hypoacusis and impaired visual acuity. Whereas, no motor or sensitive deficits were present. Cranial nerves exam, muscle tone and deep tendons reflexes were all normal. On his mini-mental status examination, he had a score of 22 objectifying a mild cognitive impairment. The rest of physical exams revealed no abnormality. Investigations included performing a brain MRI that showed bilateral hypersignal lesions, poorly bordered, in medial temporal lobe on fluid-attenuated inversion recovery (FAIR) sequence (Fig. 1). A spinal tap was done and cerebral-spinal fluid analysis was consistent with aseptic meningitis (White blood cell (WBC) count of 60/ml, glucose at 0,4g/l, and protein at 1,37g/l). An electroencephalogram (EEG) was run, it showed normal background rhythms. Fundoscopic exam revealed anterior ischemic optic neuropathy in the right eye. The audiometer on the other hand has shown severe mixed hearing loss in the right side and a presbycusis hearing loss in the left side. A full blood panel was realized; it included blood count, c-reactive protein test, renal function, liver function, thyroid function and an electrolyte panel that were all normal. Screening tests against HIV, syphilis and hepatitis B were negative. Autoantibody tests for autoimmune conditions included antinuclear antibodies (ANA), extractable nuclear antigen (ENA) and anti-neutrophil cytoplasmic antibodies (ANCA), they came up also all negative. Screening for autoimmune anti-neuronal antibodies included testing for anti-HU, anti-RI, anti-amphiphysin, anti-Ma2, anti-CV2 and anti-YO antibodies, the results were likewise negative. Performed thoraco-abdominopelvic CT scan (TAP-CT) revealed no abnormality as well. As seen beforehand, there was no diagnosis-contributive positive test, which made establishing a diagnosis quite an ordeal. The patient had bilateral floppy ears (Fig. 2), and along with the presence of hearing loss and a history of painless red eyes, the question of a possible relapsing polychondritis underlying condition was raised. And since the Michet et al. diagnostic criteria were fulfilled (Auricular cartilage inflammation, ocular inflammation and hearing loss), a limbic encephalitis diagnosis associated to RP was established. Treatment consisted on administering high dose of intravenous methylprednisolone (1g per day) for five days, relayed by tapered doses of oral corticosteroids starting by 1mg/kg per day and an immunosuppressant agent (Azathioprine) at the dose of 2 mg/kg per day. After one month, his MMS exam score went up to 28, along with significant improvement of his memory disorders, gait and balance problems.