Chemical bonding theory is of utmost importance to chemistry. We argue that there is still plenty of unexplored territory, and that both internal and external reference biases remain in the standard model of the chemical bond. The former affect the basic notion of wavefunction interference, which is purportedly recognized as the most basic bonding mechanism. The latter influence how bonding models are chosen. After unveiling these different biases, we advocate for the use of real space analyses, which are as reference-less as possible. Delocalisation emerges as the reference-less equivalent to interference and the ultimate root of bonding. Atoms (or fragments) in molecules should be understood as a statistical mixture of components differing in electron number, spin, etc.