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Research article
Christopher Miles
University of Roehampton
Corresponding Author
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Background: Osteoarthritis is a major cause of pain and disability worldwide, therefore ways of treating this condition are paramount to a successful health system. The purpose of the study was to investigate the changes in spatial-temporal gait parameters and clinical measurements following treatment with a non-invasive foot-worn biomechanical device on patients with knee osteoarthritis within the UK.
Methods: A retrospective analysis was carried out on 455 patients with knee osteoarthritis. All patients were evaluated using a computerized gait test and two self-assessment questionnaires (WOMAC and SF-36) at baseline and after 3 and 6 months of treatment. The biomechanical device is a shoe-like device with convex pods under the sole that have the capability of changing foot centre of pressure and training neuromuscular control. The device was individually calibrated for each patient to minimise symptoms whilst walking and train neuromuscular control. Patients used the device for short periods during activities of daily living. Repeated measures statistical analyses were performed to compare differences over time.
Results: After 6 months of treatment significant improvements were seen in all gait parameters (p<0.01). Specifically, gait velocity, step length and single limb support of the more symptomatic knee improved by 13%, 7.8% and 3%, respectively. These were supported by significant improvements in pain, function and quality of life (48.6%, 45.7% and 22% respectively; p<0.001). A sub-group analysis revealed no baseline differences between those who were recommended joint replacement and those who were not. Both groups improved significantly over time (p<0.05 for all).
Conclusions: Our results suggest that the personalised biomechanical treatment can improve gait patterns, pain, function and quality of life. It may provide an additional solution to managing UK patients suffering from knee osteoarthritis but needs to be tested in a controlled setting first.
Keywords
Knee osteoarthritis; Gait; Pain; Function; Biomechanical treatment
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CURRENT STATUS: Published
View the published article at BMC Musculoskeletal Disorders.
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Posted 04 Jun, 2020
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On 29 May, 2020
Editorial decision: Accept
On 28 May, 2020
Editor assigned
On 26 May, 2020
Editor invited
On 26 May, 2020
No comments provided
Editorial decision: Minor revision
On 26 May, 2020
Review #2 received
Received 23 May, 2020
Reviewer #2 agreed
On 05 May, 2020
Review #1 received
Received 03 May, 2020
Reviewer #1 agreed
On 01 May, 2020
Reviewers invited
Invitations sent on 28 Apr, 2020
Editor assigned
On 21 Apr, 2020
Submission checks complete
On 20 Apr, 2020
Editor invited
On 20 Apr, 2020
No comments provided
Editorial decision: Major revision
On 02 Apr, 2020
Review #4 received
Received 27 Mar, 2020
Review #2 received
Received 26 Mar, 2020
Review #3 received
Received 26 Mar, 2020
Reviewer #4 agreed
On 23 Mar, 2020
Reviewer #3 agreed
On 19 Mar, 2020
Review #1 received
Received 19 Mar, 2020
Reviewer #2 agreed
On 17 Mar, 2020
Reviewer #1 agreed
On 12 Mar, 2020
Reviewers invited
Invitations sent on 06 Mar, 2020
Editor assigned
On 05 Mar, 2020
Submission checks complete
On 03 Mar, 2020
Editor invited
On 02 Mar, 2020
First submitted
On 24 Feb, 2020
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Orthopedics
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A new preprint design is coming!
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See the published version of this preprint at BMC Musculoskeletal Disorders.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Christopher Miles
University of Roehampton
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Musculoskeletal Disorders.
Version 3
Posted 04 Jun, 2020
No community comments so far
Submission checks complete
On 29 May, 2020
Editorial decision: Accept
On 28 May, 2020
Editor assigned
On 26 May, 2020
Editor invited
On 26 May, 2020
No comments provided
Editorial decision: Minor revision
On 26 May, 2020
Review #2 received
Received 23 May, 2020
Reviewer #2 agreed
On 05 May, 2020
Review #1 received
Received 03 May, 2020
Reviewer #1 agreed
On 01 May, 2020
Reviewers invited
Invitations sent on 28 Apr, 2020
Editor assigned
On 21 Apr, 2020
Submission checks complete
On 20 Apr, 2020
Editor invited
On 20 Apr, 2020
No comments provided
Editorial decision: Major revision
On 02 Apr, 2020
Review #4 received
Received 27 Mar, 2020
Review #2 received
Received 26 Mar, 2020
Review #3 received
Received 26 Mar, 2020
Reviewer #4 agreed
On 23 Mar, 2020
Reviewer #3 agreed
On 19 Mar, 2020
Review #1 received
Received 19 Mar, 2020
Reviewer #2 agreed
On 17 Mar, 2020
Reviewer #1 agreed
On 12 Mar, 2020
Reviewers invited
Invitations sent on 06 Mar, 2020
Editor assigned
On 05 Mar, 2020
Submission checks complete
On 03 Mar, 2020
Editor invited
On 02 Mar, 2020
First submitted
On 24 Feb, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Musculoskeletal Disorders.
Background: Osteoarthritis is a major cause of pain and disability worldwide, therefore ways of treating this condition are paramount to a successful health system. The purpose of the study was to investigate the changes in spatial-temporal gait parameters and clinical measurements following treatment with a non-invasive foot-worn biomechanical device on patients with knee osteoarthritis within the UK.
Methods: A retrospective analysis was carried out on 455 patients with knee osteoarthritis. All patients were evaluated using a computerized gait test and two self-assessment questionnaires (WOMAC and SF-36) at baseline and after 3 and 6 months of treatment. The biomechanical device is a shoe-like device with convex pods under the sole that have the capability of changing foot centre of pressure and training neuromuscular control. The device was individually calibrated for each patient to minimise symptoms whilst walking and train neuromuscular control. Patients used the device for short periods during activities of daily living. Repeated measures statistical analyses were performed to compare differences over time.
Results: After 6 months of treatment significant improvements were seen in all gait parameters (p<0.01). Specifically, gait velocity, step length and single limb support of the more symptomatic knee improved by 13%, 7.8% and 3%, respectively. These were supported by significant improvements in pain, function and quality of life (48.6%, 45.7% and 22% respectively; p<0.001). A sub-group analysis revealed no baseline differences between those who were recommended joint replacement and those who were not. Both groups improved significantly over time (p<0.05 for all).
Conclusions: Our results suggest that the personalised biomechanical treatment can improve gait patterns, pain, function and quality of life. It may provide an additional solution to managing UK patients suffering from knee osteoarthritis but needs to be tested in a controlled setting first.
Figure 1
Figure 2
Figure 3
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