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Research article
Christoph von Schulze Pellengahr
Agaplesion Ev. Bathildiskrankenhaus Bad Pyrmont
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5596-6003
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This work is licensed under a CC BY 4.0 License. Read Full License
Background: High primary stability is the key prerequisite for safe osseointegration of cementless intervertebral disc prosthesis. The aim of our study was to determine the primary stability of intervertebral disc prosthesis with two different anchoring concepts – keel and spike anchoring.
Methods: 10 ActivL intervertebral disc prosthesis (5 x keel anchoring, 5 x spike anchoring) implanted in human cadaver lumbar spine specimens were tested in a spine movement simulator. Under axial load flexion, extension, left and right bending and axial rotation were applied on the lumbar spine specimens through a defined three-dimensional movement program as per ISO 2631 and ISO/CD 18192-1.3 standards. Micromotion of the implants covering every single movement axis were measured for both anchor types and compared using Student’s T-test for significance after calculating 95% confidence intervals.
Results: In the transverse axis, the keel anchoring concept showed lower statistically significant (p<0.05) mean values of micromotion compared to spike anchoring concept. The highest micromotion values for both types were observed in the longitudinal axis. The data achieved the threshold of primary stability (150-200 μm).
Conclusions: Both fixation systems fulfil the required criteria of primary stability. Independent of the selected anchorage type an immediate postoperative active mobilization doesn’t compromise the stability of the prostheses.
Keywords
primary stability of intervertebral disc prosthesis, micromotions, Aesculap ActivL, anchoring concept, keel, spikes
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Peer Review Timeline
CURRENT STATUS: Under Review
Version 2
Posted 07 Jan, 2021
No community comments so far
Editorial decision: Major revision
On 03 Feb, 2021
Review #1 received
Received 01 Feb, 2021
Reviewer #2 agreed
On 08 Jan, 2021
Review #2 received
Received 08 Jan, 2021
Reviewer #1 agreed
On 04 Jan, 2021
Editor assigned
On 03 Jan, 2021
Reviewers invited
Invitations sent on 03 Jan, 2021
Editor invited
On 03 Jan, 2021
Submission checks complete
On 24 Dec, 2020
No comments provided
Editorial decision: Major revision
On 26 May, 2020
Review #2 received
Received 16 May, 2020
Review #1 received
Received 09 Apr, 2020
Reviewer #1 agreed
On 26 Mar, 2020
Reviewer #2 agreed
On 26 Mar, 2020
Reviewers invited
Invitations sent on 12 Mar, 2020
Editor assigned
On 09 Mar, 2020
Submission checks complete
On 05 Mar, 2020
Editor invited
On 05 Mar, 2020
First submitted
On 01 Mar, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedics
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A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
This preprint is under consideration at BMC Musculoskeletal Disorders. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Christoph von Schulze Pellengahr
Agaplesion Ev. Bathildiskrankenhaus Bad Pyrmont
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5596-6003
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 2
Posted 07 Jan, 2021
No community comments so far
Editorial decision: Major revision
On 03 Feb, 2021
Review #1 received
Received 01 Feb, 2021
Reviewer #2 agreed
On 08 Jan, 2021
Review #2 received
Received 08 Jan, 2021
Reviewer #1 agreed
On 04 Jan, 2021
Editor assigned
On 03 Jan, 2021
Reviewers invited
Invitations sent on 03 Jan, 2021
Editor invited
On 03 Jan, 2021
Submission checks complete
On 24 Dec, 2020
No comments provided
Editorial decision: Major revision
On 26 May, 2020
Review #2 received
Received 16 May, 2020
Review #1 received
Received 09 Apr, 2020
Reviewer #1 agreed
On 26 Mar, 2020
Reviewer #2 agreed
On 26 Mar, 2020
Reviewers invited
Invitations sent on 12 Mar, 2020
Editor assigned
On 09 Mar, 2020
Submission checks complete
On 05 Mar, 2020
Editor invited
On 05 Mar, 2020
First submitted
On 01 Mar, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: High primary stability is the key prerequisite for safe osseointegration of cementless intervertebral disc prosthesis. The aim of our study was to determine the primary stability of intervertebral disc prosthesis with two different anchoring concepts – keel and spike anchoring.
Methods: 10 ActivL intervertebral disc prosthesis (5 x keel anchoring, 5 x spike anchoring) implanted in human cadaver lumbar spine specimens were tested in a spine movement simulator. Under axial load flexion, extension, left and right bending and axial rotation were applied on the lumbar spine specimens through a defined three-dimensional movement program as per ISO 2631 and ISO/CD 18192-1.3 standards. Micromotion of the implants covering every single movement axis were measured for both anchor types and compared using Student’s T-test for significance after calculating 95% confidence intervals.
Results: In the transverse axis, the keel anchoring concept showed lower statistically significant (p<0.05) mean values of micromotion compared to spike anchoring concept. The highest micromotion values for both types were observed in the longitudinal axis. The data achieved the threshold of primary stability (150-200 μm).
Conclusions: Both fixation systems fulfil the required criteria of primary stability. Independent of the selected anchorage type an immediate postoperative active mobilization doesn’t compromise the stability of the prostheses.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
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