1.
Li HP, Yang WJ, Qu SX, Pei F, Luo X, Mariga AM, Ma L. Variation of volatile terpenes
in the edible fungi mycelia Flammulina velutipes and communications in fungus-mite interactions. Food Res Int.2018;103:150-55.
2.
Cai H, Liu X, Chen Z, Liao S, Zou Y. Isolation, purification and identification of
nine chemical compounds from Flammulina velutipes fruiting bodies. Food Chem.2013;141(3):2873-9.
3.
Liu JY, Chang MC, Meng JL, Feng CP, Zhao H, Zhang ML. Comparative Proteome Reveals
Metabolic Changes during the Fruiting Process in Flammulina velutipes. J Agric Food Chem.2017;65(24):5091-100.
4.
Smiderle FR, Carbonero ER, Sassaki GL, Gorin PAJ, Iacomini M. Characterization of
a heterogalactan: Some nutritional values of the edible mushroom Flammulina velutipes. Food Chemistry.2008;108(1):329-33.
5.
Chang YC, Hsiao YM, Wu MF, Ou CC, Lin YW, Lue KH, Ko JL. Interruption of lung cancer
cell migration and proliferation by fungal immunomodulatory protein FIP-fve from Flammulina velutipes. J Agric Food Chem.2013;61(49):12044-52.
6.
Ma Z, Cui F, Gao X, Zhang J, Zheng L, Jia L. Purification, characterization, antioxidant
activity and anti-aging of exopolysaccharides by Flammulina velutipes SF-06. Antonie Van Leeuwenhoek.2015;107(1):73-82.
7.
Yin H, Wang Y, Wang Y, Chen T, Tang H, Wang M. Purification, characterization and
immuno-modulating properties of polysaccharides isolated from Flammulina velutipes mycelium. Am J Chin Med.2010;38(1):191-204.
8.
Yang W, Fang Y, Liang J, Hu Q. Optimization of ultrasonic extraction of Flammulina velutipes polysaccharides and evaluation of its acetylcholinesterase inhibitory activity. Food
Research International.2011;44(5):1269-75.
9.
Wu DM, Duan WQ, Liu Y, Cen Y. Anti-inflammatory effect of the polysaccharides of golden
needle mushroom in burned rats. Int J Biol Macromol.2010;46(1):100-3.
10.
El Enshasy HA, Hatti-Kaul R. Mushroom immunomodulators: unique molecules with unlimited
applications. Trends Biotechnol.2013;31(12):668-77.
11.
Xiao H, Zhong JJ. Production of Useful Terpenoids by Higher-Fungus Cell Factory and
Synthetic Biology Approaches. Trends Biotechnol.2016;34(3):242-55.
12.
Shao S, Hernandez M, Kramer JK, Rinker DL, Tsao R. Ergosterol profiles, fatty acid
composition, and antioxidant activities of button mushrooms as affected by tissue
part and developmental stage. J Agric Food Chem.2010;58(22):11616-25.
13.
Yi C, Zhong H, Tong S, Cao X, Firempong C, Liu H, et al. Enhanced oral bioavailability
of a sterol-loaded microemulsion formulation of Flammulina velutipes, a potential antitumor drug. Int J Nanomedicine. 2012;7:5067-78.
14.
Tong S, Zhong H, Yi C, Cao X, Firempong CK, Zheng Q, Feng Y, Yu J, Xu X. Simultaneous
HPLC determination of ergosterol and 22,23-dihydroergosterol in Flammulina velutipes sterol-loaded microemulsion. Biomed Chromatogr.2014;28(2):247-54.
15.
Yi C, Sun C, Tong S, Cao X, Feng Y, Firempong CK, Jiang X, Xu X, Yu J. Cytotoxic effect
of novel Flammulina velutipes sterols and its oral bioavailability via mixed micellar nanoformulation. Int J Pharm.2013;448(1):44-50.
16.
Ma L, Chen H, Dong P, Lu X. Anti-inflammatory and anticancer activities of extracts
and compounds from the mushroom Inonotus obliquus. Food Chem.2013;139:503-8.
17.
Sharma M, Sasvari Z, Nagy PD. Inhibition of sterol biosynthesis reduces tombusvirus
replication in yeast and plants. J Virol.2010;84(5):2270-81.
18.
Hui KP, Kuok DI, Kang SS, Li HS, Ng MM, Bui CH, Peiris JS, Chan RW, Chan MC. Modulation
of sterol biosynthesis regulates viral replication and cytokine production in influenza
A virus infected human alveolar epithelial cells. Antiviral Res.2015;119:1-7.
19.
Blanc M, Hsieh WY, Robertson KA, Watterson S, Shui G, Lacaze P, et al. Host defense
against viral infection involves interferon mediated down-regulation of sterol biosynthesis.
PLoS Biol.2011;9(3):e1000598.
20.
Palmie-Peixoto IV, Rocha MR, Urbina JA, de Souza W, Einicker-Lamas M, Motta MC. Effects
of sterol biosynthesis inhibitors on endosymbiont-bearing trypanosomatids. FEMS Microbiol
Lett.2006;255(1):33-42.
21.
Tan W, Pan M, Liu H, Tian H, Ye Q, Liu H. Ergosterol peroxide inhibits ovarian cancer
cell growth through multiple pathways. Onco Targets Ther.2017;10:3467-74.
22.
Rhee YH, Jeong SJ, Lee HJ, Lee HJ, Koh W, Jung JH, Kim SH, Sung-Hoon K. Inhibition
of STAT3 signaling and induction of SHP1 mediate antiangiogenic and antitumor activities
of ergosterol peroxide in U266 multiple myeloma cells. BMC Cancer.2012;12:28.
23.
Shimizu T, Kawai J, Ouchi K, Kikuchi H, Osima Y, Hidemi R. Agarol, an ergosterol derivative
from Agaricus blazei, induces caspase-independent apoptosis in human cancer cells. Int J Oncol.2016;48(4):1670-8.
24.
Li X, Wu Q, Xie Y, Ding Y, Du WW, Sdiri M, Yang BB. Ergosterol purified from medicinal
mushroom Amauroderma rude inhibits cancer growth in vitro and in vivo by up-regulating multiple tumor
suppressors. Oncotarget.2015;6(19):17832-46.
25.
Pluchino LA, Liu AK, Wang HC. Reactive oxygen species-mediated breast cell carcinogenesis
enhanced by multiple carcinogens and intervened by dietary ergosterol and mimosine.
Free Radic Biol Med.2015;80:12-26.
26.
Ma BX, Ke X, Tang XL, Zheng RC, Zheng YG. Rate-limiting steps in the Saccharomyces cerevisiae ergosterol pathway: towards improved ergosta-5,7-dien-3beta-ol accumulation by metabolic
engineering. World J Microbiol Biotechnol.2018;34(4):55.
27.
Souza CM, Schwabe TM, Pichler H, Ploier B, Leitner E, Guan XL, Wenk MR, Riezman I,
Riezman H. A stable yeast strain efficiently producing cholesterol instead of ergosterol
is functional for tryptophan uptake, but not weak organic acid resistance. Metab Eng.2011;13(5):555-69.
28.
Zhang K, Tong M, Gao K, Di Y, Wang P, Zhang C, Wu X, Zheng D. Genomic reconstruction
to improve bioethanol and ergosterol production of industrial yeast Saccharomyces cerevisiae. J Ind Microbiol Biotechnol.2015;42(2):207-18.
29.
Yuan J, Ching CB. Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae. Microb Cell Fact.2015;14:38.
30.
Hu Z, He B, Ma L, Sun Y, Niu Y, Zeng B. Recent Advances in Ergosterol Biosynthesis
and Regulation Mechanisms in Saccharomyces cerevisiae. Indian J Microbiol.2017;57(3):270-77.
31.
Alcazar-Fuoli L, Mellado E, Garcia-Effron G, Lopez JF, Grimalt JO, Cuenca-Estrella
JM, Rodriguez-Tudela JL. Ergosterol biosynthesis pathway in Aspergillus fumigatus. Steroids.2008;73(3):339-47.
32.
Layer JV, Barnes BM, Yamasaki Y, Barbuch R, Li L, Taramino S, Balliano G, Bard M.
Characterization of a mutation that results in independence of oxidosqualene cyclase
(Erg7) activity from the downstream 3-ketoreductase (Erg27) in the yeast ergosterol
biosynthetic pathway. Biochim Biophys Acta.2013;1831(2):361-9.
33.
Long N, Xu X, Zeng Q, Sang H, Lu L. Erg4A and Erg4B Are Required for Conidiation and
Azole Resistance via Regulation of Ergosterol Biosynthesis in Aspergillus fumigatus. Appl Environ Microbiol.2017;83(4):e02924-16.
34.
Wriessnegger T, Pichler H. Yeast metabolic engineering--targeting sterol metabolism
and terpenoid formation. Prog Lipid Res.2013;52(3):277-93.
35.
Wu Q, Wu J, Li SS, Zhang HJ, Feng CY, Yin DD, Wu RY, Wang LS. Transcriptome sequencing
and metabolite analysis for revealing the blue flower formation in waterlily. BMC
Genomics.2016;17(1):897.
36.
Wei G, Tian P, Zhang F, Qin H, Miao H, Chen Q, et al. Integrative Analyses of Nontargeted
Volatile Profiling and Transcriptome Data Provide Molecular Insight into VOC Diversity
in Cucumber Plants (Cucumis sativus). Plant Physiol.2016;172(1):603-18.
37.
Szymanski J, Brotman Y, Willmitzer L, Cuadros-Inostroza A. Linking gene expression
and membrane lipid composition of Arabidopsis. Plant Cell.2014;26(3):915-28.
38.
Chen S, Xu J, Liu C, Zhu Y, Nelson DR, Zhou S, et al. Genome sequence of the model
medicinal mushroom Ganoderma lucidum. Nat Commun.2012;3:913.
39.
Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment
of short DNA sequences to the human genome. Genome Biol.2009;10(3):25.
40.
Li B, Dewey CN. RSEM: accurate transcript quantification from RNA-Seq data with or
without a reference genome. BMC Bioinformatics.2011;12:323.
41.
Anders S, Huber W. Differential expression analysis for sequence count data. Genome
Biol.2010;11(10):106.
42.
Huang JF, Shen ZY, Mao QL, Zhang XM, Zhang B, Wu JS, Liu ZQ, Zheng YG. Systematic
Analysis of Bottlenecks in a Multibranched and Multilevel Regulated Pathway: The Molecular
Fundamentals of l-Methionine Biosynthesis in Escherichia coli. ACS Synth Biol.2018;7(11):2577-89.
43.
Hsu HH, Araki M, Mochizuki M, Hori Y, Murata M, Kahar P, Yoshida T, Hasunuma T, Kondo
A. A Systematic Approach to Time-series Metabolite Profiling and RNA-seq Analysis
of Chinese Hamster Ovary Cell Culture. Sci Rep.2017;7:43518.
44.
Kang LZ, Zeng XL, Ye ZW, Lin JF, Guo LQ. Compositional analysis of the fruiting body
of transgenic Flammulina velutipes producing resveratrol. Food Chem.2014;164:211-8.
45.
Wang Y, Bao L, Yang X, Li L, Li S, Gao H, Yao XS, Wen H, Liu HW. Bioactive sesquiterpenoids
from the solid culture of the edible mushroom Flammulina velutipes growing on cooked rice. Food Chem.2012;132(3):1346-53.
46.
Veen M, Stahl U, Lang C. Combined overexpression of genes of the ergosterol biosynthetic
pathway leads to accumulation of sterols in Saccharomyces cerevisiae. FEMS Yeast Res.2003;4(1):87-95.
47.
Cardoza RE, Vizcaino JA, Hermosa MR, Sousa S, Gonzalez FJ, Llobell A, Monte E, Gutierrez
S. Cloning and characterization of the erg1 gene of Trichoderma harzianum: effect of the erg1 silencing on ergosterol biosynthesis and resistance to terbinafine.
Fungal Genet Biol.2006;43(3):164-78.
48.
Gachotte D, Barbuch R, Gaylor J, Nickel E, Bard M. Characterization of the Saccharomyces cerevisiae ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) involved in sterol
biosynthesis. Proc Natl Acad Sci U S A.1998;95(23):13794-9.
49.
Swain E, Baudry K, Stukey J, McDonough V, Germann M, Nickels JT, Jr. Sterol-dependent
regulation of sphingolipid metabolism in Saccharomyces cerevisiae. J Biol Chem.2002;277(29):26177-84.
50.
Trocha PJ, Sprinson DB. Location and regulation of early enzymes of sterol biosynthesis
in yeast. Arch Biochem Biophys.1976;174(1):45-51.
51.
Dimster-Denk D, Rine J. Transcriptional regulation of a sterol-biosynthetic enzyme
by sterol levels in Saccharomyces cerevisiae. Mol Cell Biol.1996;16(8):3981-9.
52.
Ghodasara A, Voigt CA. Balancing gene expression without library construction via
a reusable sRNA pool. Nucleic Acids Res.2017;45(13):8116-27.
53.
Yang H, Tong J, Lee CW, Ha S, Eom SH, Im YJ. Structural mechanism of ergosterol regulation
by fungal sterol transcription factor Upc2. Nat Commun.2015;6:6129.
54.
Dunkel N, Liu TT, Barker KS, Homayouni R, Morschhauser J, Rogers PD. A gain-of-function
mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance
in a clinical Candida albicans isolate. Eukaryot Cell.2008;7(7):1180-90.
55.
MacPherson S, Akache B, Weber S, De Deken X, Raymond M, Turcotte B. Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator
of ergosterol biosynthetic genes. Antimicrob Agents Chemother.2005;49(5):1745-52.
56.
Silver PM, Oliver BG, White TC. Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism. Eukaryot Cell.2004;3(6):1391-7.
57.
Zhou P, Xie W, Li A, Wang F, Yao Z, Bian Q, Zhu Y, Yu H, Ye L. Alleviation of metabolic
bottleneck by combinatorial engineering enhanced astaxanthin synthesis in Saccharomyces cerevisiae. Enzyme Microb Technol.2017;100:28-36.