This article aims to identify the factors that influence the choice of adaptation measures by market garden producers in the extreme south of Mali in the face of climate change. The study used a multinomial logit regression model based on data collected from producers. Interviews with 194 producers were conducted in 3 circles in the southern region: Sikasso, Koutiala and Bougouni. The results of the multinomial logit model indicate that the mode of access to land, access to information on climate change, agricultural extension, agricultural experience and access to credit are the main endogenous strategies developed by producers to counteract the impacts of climate change. Finally, in order to consolidate these different strategies developed by producers, campaigns to raise awareness among producers on the importance of adapting to climate change should be encouraged.