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Research article
Dao-Xin Wang
Chongqing Medical University
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4644-5377
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Since December 2019,more than 80 thousand patients with coronavirus disease 2019 (COVID-19) has been confirmed in China. With the increasing number of recovered patients, more attention should be paid to the follow-up of patients.
Methods: In the study, 576 patients with COVID-19 discharged from hospital in Chongqing, China from January 24, 2020, to March 10, 2020 were evaluated by viral nucleic acid tests for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) to determine if they could be released from quarantine. Among the 576 patients, 61 patients (10.6%) had positive results for SARS-CoV-2. We aimed to analyze the demographics, clinical characteristics and treatment of 61 patients.
Results: These positive patients were characterized by older age, chronic medical illness and mild conditions. Asymptom and normalities on chest radiograph were found in most of the positive patients with COVID-19. Also, they showed positive results by stool or sputum specimen with negative results by nasal and throat swab. The median duration of positive result for SARS-CoV-2 was varied from 3 days to 35 days after hospital discharge with no family member infection.
Conclusions: Multi-site screening of SARS-CoV-2 including nasal and throat swab, stool and sputum samples could be considered to improve the diagnosis, treatment and infection control in patients with COVID-19. Our findings provide the important information and clinical evidence for the improved management of patients recovered from COVID-19
Keywords
coronavirus disease 2019;hospital discharge; SARS-CoV-2
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CURRENT STATUS: Published
View the published article at BMC Infectious Diseases.
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On 09 Jun, 2020
Editorial decision: Accept
On 09 Jun, 2020
No comments provided
Editorial decision: Minor revision
On 08 Jun, 2020
Editor assigned
On 03 Jun, 2020
Submission checks complete
On 02 Jun, 2020
Editor invited
On 02 Jun, 2020
Version 2
Posted 19 May, 2020
No comments provided
Review #2 received
Received 28 May, 2020
Editorial decision: Minor revision
On 28 May, 2020
Review #3 received
Received 18 May, 2020
Reviewer #3 agreed
On 17 May, 2020
Reviewer #2 agreed
On 14 May, 2020
Review #1 received
Received 09 May, 2020
Reviewers invited
Invitations sent on 09 May, 2020
Reviewer #1 agreed
On 09 May, 2020
Editor assigned
On 08 May, 2020
Editor invited
On 07 May, 2020
Submission checks complete
On 19 Mar, 2020
No comments provided
Editorial decision: Major revision
On 28 Apr, 2020
Review #2 received
Received 22 Apr, 2020
Review #1 received
Received 11 Apr, 2020
Reviewer #2 agreed
On 09 Apr, 2020
Reviewer #1 agreed
On 31 Mar, 2020
Reviewers invited
Invitations sent on 30 Mar, 2020
Editor assigned
On 19 Mar, 2020
Submission checks complete
On 18 Mar, 2020
Editor invited
On 18 Mar, 2020
First submitted
On 16 Mar, 2020
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Infectious Diseases
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A new preprint design is coming!
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See the published version of this preprint at BMC Infectious Diseases.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Dao-Xin Wang
Chongqing Medical University
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4644-5377
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Infectious Diseases.
No community comments so far
Submission checks complete
On 09 Jun, 2020
Editorial decision: Accept
On 09 Jun, 2020
No comments provided
Editorial decision: Minor revision
On 08 Jun, 2020
Editor assigned
On 03 Jun, 2020
Submission checks complete
On 02 Jun, 2020
Editor invited
On 02 Jun, 2020
Version 2
Posted 19 May, 2020
No comments provided
Review #2 received
Received 28 May, 2020
Editorial decision: Minor revision
On 28 May, 2020
Review #3 received
Received 18 May, 2020
Reviewer #3 agreed
On 17 May, 2020
Reviewer #2 agreed
On 14 May, 2020
Review #1 received
Received 09 May, 2020
Reviewers invited
Invitations sent on 09 May, 2020
Reviewer #1 agreed
On 09 May, 2020
Editor assigned
On 08 May, 2020
Editor invited
On 07 May, 2020
Submission checks complete
On 19 Mar, 2020
No comments provided
Editorial decision: Major revision
On 28 Apr, 2020
Review #2 received
Received 22 Apr, 2020
Review #1 received
Received 11 Apr, 2020
Reviewer #2 agreed
On 09 Apr, 2020
Reviewer #1 agreed
On 31 Mar, 2020
Reviewers invited
Invitations sent on 30 Mar, 2020
Editor assigned
On 19 Mar, 2020
Submission checks complete
On 18 Mar, 2020
Editor invited
On 18 Mar, 2020
First submitted
On 16 Mar, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Infectious Diseases
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Infectious Diseases.
Background: Since December 2019,more than 80 thousand patients with coronavirus disease 2019 (COVID-19) has been confirmed in China. With the increasing number of recovered patients, more attention should be paid to the follow-up of patients.
Methods: In the study, 576 patients with COVID-19 discharged from hospital in Chongqing, China from January 24, 2020, to March 10, 2020 were evaluated by viral nucleic acid tests for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) to determine if they could be released from quarantine. Among the 576 patients, 61 patients (10.6%) had positive results for SARS-CoV-2. We aimed to analyze the demographics, clinical characteristics and treatment of 61 patients.
Results: These positive patients were characterized by older age, chronic medical illness and mild conditions. Asymptom and normalities on chest radiograph were found in most of the positive patients with COVID-19. Also, they showed positive results by stool or sputum specimen with negative results by nasal and throat swab. The median duration of positive result for SARS-CoV-2 was varied from 3 days to 35 days after hospital discharge with no family member infection.
Conclusions: Multi-site screening of SARS-CoV-2 including nasal and throat swab, stool and sputum samples could be considered to improve the diagnosis, treatment and infection control in patients with COVID-19. Our findings provide the important information and clinical evidence for the improved management of patients recovered from COVID-19
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