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Research article
Feasibility and impact of laparoscopic sleeve gastrectomy after renal transplantation on comorbidities, graft function and quality of life.
Naif Alenazi
Prince Mohammed Bin Abdul Aziz Hospital
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The aim of this study is to clarify the feasibility and effect of laparoscopic sleeve gastrectomy (LSG) on comorbidities, graft function and quality of life in patients who underwent renal transplantation (RT)
Methods: This is a retrospective review of 5 patients who underwent LSG after RT. Demographic data, anthropometric parameters, the effect on comorbidities, postoperative course, immunosuppressive medications, causes of RT, renal function, the survival of graft, and quality of life after SG in obese patients with a history of RT were assessed using BAROS–Moorhead–Ardelt survey
Results From September 2015 to September 2019, 5 renal transplant patients underwent LSG; 60% were female, and 40 were male. Median body mass index (BMI) decreased from 42.17 kg/m2 (range 36–55) before surgery to 28.16 kg/m2 (range 25–42) after surgery. Improvement in blood pressure, triglyceride, and cholesterol levels was observed, and all cases were able to decrease their medications. Insulin was stopped and replaced with linagliptin in all diabetic patients. Graft function improved, and proteinuria level decreased in all cases (100%). All patients reported to have an excellent quality of life.
Conclusion: LSG showed excellent outcomes in this high-risk group of patients regarding comorbidities, graft function and quality of life
Keywords
Renal transplantation, sleeve gastrectomy, hypertension, dyslipidemia, graft function
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CURRENT STATUS: Under Revision
Version 2
Posted 17 Apr, 2020
No community comments so far
Editorial decision: Minor revision
On 10 Jan, 2021
Review #2 received
Received 19 Jul, 2020
Review #1 received
Received 18 Jul, 2020
Reviewer #2 agreed
On 27 Jun, 2020
Reviewers invited
Invitations sent on 24 Jun, 2020
Reviewer #1 agreed
On 24 Jun, 2020
Editor assigned
On 13 Apr, 2020
Submission checks complete
On 12 Apr, 2020
Editor invited
On 12 Apr, 2020
No comments provided
Editorial decision: Major revision
On 04 Apr, 2020
Review #3 received
Received 03 Apr, 2020
Reviewer #3 agreed
On 30 Mar, 2020
Review #2 received
Received 28 Mar, 2020
Review #1 received
Received 27 Mar, 2020
Reviewer #2 agreed
On 18 Mar, 2020
Submission checks complete
On 17 Mar, 2020
Editor assigned
On 17 Mar, 2020
Editor invited
On 17 Mar, 2020
Reviewers invited
Invitations sent on 17 Mar, 2020
Reviewer #1 agreed
On 17 Mar, 2020
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This preprint is under consideration at BMC Surgery. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Feasibility and impact of laparoscopic sleeve gastrectomy after renal transplantation on comorbidities, graft function and quality of life.
Naif Alenazi
Prince Mohammed Bin Abdul Aziz Hospital
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Revision
Version 2
Posted 17 Apr, 2020
No community comments so far
Editorial decision: Minor revision
On 10 Jan, 2021
Review #2 received
Received 19 Jul, 2020
Review #1 received
Received 18 Jul, 2020
Reviewer #2 agreed
On 27 Jun, 2020
Reviewers invited
Invitations sent on 24 Jun, 2020
Reviewer #1 agreed
On 24 Jun, 2020
Editor assigned
On 13 Apr, 2020
Submission checks complete
On 12 Apr, 2020
Editor invited
On 12 Apr, 2020
No comments provided
Editorial decision: Major revision
On 04 Apr, 2020
Review #3 received
Received 03 Apr, 2020
Reviewer #3 agreed
On 30 Mar, 2020
Review #2 received
Received 28 Mar, 2020
Review #1 received
Received 27 Mar, 2020
Reviewer #2 agreed
On 18 Mar, 2020
Submission checks complete
On 17 Mar, 2020
Editor assigned
On 17 Mar, 2020
Editor invited
On 17 Mar, 2020
Reviewers invited
Invitations sent on 17 Mar, 2020
Reviewer #1 agreed
On 17 Mar, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The aim of this study is to clarify the feasibility and effect of laparoscopic sleeve gastrectomy (LSG) on comorbidities, graft function and quality of life in patients who underwent renal transplantation (RT)
Methods: This is a retrospective review of 5 patients who underwent LSG after RT. Demographic data, anthropometric parameters, the effect on comorbidities, postoperative course, immunosuppressive medications, causes of RT, renal function, the survival of graft, and quality of life after SG in obese patients with a history of RT were assessed using BAROS–Moorhead–Ardelt survey
Results From September 2015 to September 2019, 5 renal transplant patients underwent LSG; 60% were female, and 40 were male. Median body mass index (BMI) decreased from 42.17 kg/m2 (range 36–55) before surgery to 28.16 kg/m2 (range 25–42) after surgery. Improvement in blood pressure, triglyceride, and cholesterol levels was observed, and all cases were able to decrease their medications. Insulin was stopped and replaced with linagliptin in all diabetic patients. Graft function improved, and proteinuria level decreased in all cases (100%). All patients reported to have an excellent quality of life.
Conclusion: LSG showed excellent outcomes in this high-risk group of patients regarding comorbidities, graft function and quality of life
Figure 1
Figure 2