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Research article
Ding-Cheng Chan
Corresponding Author
ORCiD: https://orcid.org/0000-0003-2215-2243
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Background The three geriatric conditions, depression, dementia and delirium (3D’s), are common among hospitalized older patients and often lead to impairments of activities of daily living. The aim of this study is to explore the impact of depression, dementia and delirium on activities of daily living (ADLs) during and after hospitalization. Methods A prospective cohort study was conducted between 2012 and 2013 in a tertiary medical center in Taiwan. Patients aged 65 years and older admitted to the geriatric ward were invited to this study. Geriatric Depression Scale Short Form, Mini-Mental State and Confusion Assessment Method were used to identify patients with depression, dementia and delirium on admission, respectively. Barthel Index (BI) was used to evaluate patients’ functional status on admission, at discharge, 30-day, 90-day and 180-day after discharge. Generalized Estimating Equation was used to calculate the associations between 3 D’s and BI. Results One-hundred-and-forty-nine patients were included in this study. Twenty-seven patients (18.1%) had depression, 37 (24.8%) had dementia, and 85 (57.0%) had delirium. There were significant lower BI scores in patients with dementia and delirium compared with those without up to 180 days after discharge, but no difference was seen in the depression group. In general, patients had delirium or dementia had worsening functional status, even though significant magnitude of improvements on BI scores after discharge. Conclusions Depression does not affect patients’ ADLs. On the other hand, dementia and delirium can persistently limit patients’ physical function. Future care should focus more on dementia and delirium to restore function.
Keywords
Functional status; Geriatric syndrome; Hospitalization
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CURRENT STATUS: Published
View the published article at BMC Geriatrics.
Version 4
Posted 02 Oct, 2019
No community comments so far
Submission checks complete
On 07 Nov, 2019
Editorial decision: Accept
On 26 Sep, 2019
Editor assigned
On 25 Sep, 2019
Editor invited
On 24 Sep, 2019
No comments provided
Editorial decision: Minor revision
On 24 Sep, 2019
No comments provided
Editorial decision: Minor revision
On 23 Sep, 2019
Review #2 received
Received 17 Sep, 2019
Reviewer #2 agreed
On 12 Sep, 2019
Reviewer #1 agreed
On 10 Sep, 2019
Review #1 received
Received 10 Sep, 2019
Reviewers invited
Invitations sent on 07 Sep, 2019
Editor assigned
On 06 Sep, 2019
Submission checks complete
On 05 Sep, 2019
Editor invited
On 05 Sep, 2019
No comments provided
Editorial decision: Major revision
On 09 Aug, 2019
Review #2 received
Received 03 Aug, 2019
Reviewer #2 agreed
On 25 Jul, 2019
Review #1 received
Received 18 Jul, 2019
Reviewer #1 agreed
On 13 Jul, 2019
Reviewers invited
Invitations sent on 11 Jul, 2019
Editor assigned
On 18 Jun, 2019
Submission checks complete
On 17 Jun, 2019
Editor invited
On 17 Jun, 2019
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A new preprint design is coming!
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See the published version of this preprint at BMC Geriatrics.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Ding-Cheng Chan
Corresponding Author
ORCiD: https://orcid.org/0000-0003-2215-2243
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Geriatrics.
Version 4
Posted 02 Oct, 2019
No community comments so far
Submission checks complete
On 07 Nov, 2019
Editorial decision: Accept
On 26 Sep, 2019
Editor assigned
On 25 Sep, 2019
Editor invited
On 24 Sep, 2019
No comments provided
Editorial decision: Minor revision
On 24 Sep, 2019
No comments provided
Editorial decision: Minor revision
On 23 Sep, 2019
Review #2 received
Received 17 Sep, 2019
Reviewer #2 agreed
On 12 Sep, 2019
Reviewer #1 agreed
On 10 Sep, 2019
Review #1 received
Received 10 Sep, 2019
Reviewers invited
Invitations sent on 07 Sep, 2019
Editor assigned
On 06 Sep, 2019
Submission checks complete
On 05 Sep, 2019
Editor invited
On 05 Sep, 2019
No comments provided
Editorial decision: Major revision
On 09 Aug, 2019
Review #2 received
Received 03 Aug, 2019
Reviewer #2 agreed
On 25 Jul, 2019
Review #1 received
Received 18 Jul, 2019
Reviewer #1 agreed
On 13 Jul, 2019
Reviewers invited
Invitations sent on 11 Jul, 2019
Editor assigned
On 18 Jun, 2019
Submission checks complete
On 17 Jun, 2019
Editor invited
On 17 Jun, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Geriatrics.
Background The three geriatric conditions, depression, dementia and delirium (3D’s), are common among hospitalized older patients and often lead to impairments of activities of daily living. The aim of this study is to explore the impact of depression, dementia and delirium on activities of daily living (ADLs) during and after hospitalization. Methods A prospective cohort study was conducted between 2012 and 2013 in a tertiary medical center in Taiwan. Patients aged 65 years and older admitted to the geriatric ward were invited to this study. Geriatric Depression Scale Short Form, Mini-Mental State and Confusion Assessment Method were used to identify patients with depression, dementia and delirium on admission, respectively. Barthel Index (BI) was used to evaluate patients’ functional status on admission, at discharge, 30-day, 90-day and 180-day after discharge. Generalized Estimating Equation was used to calculate the associations between 3 D’s and BI. Results One-hundred-and-forty-nine patients were included in this study. Twenty-seven patients (18.1%) had depression, 37 (24.8%) had dementia, and 85 (57.0%) had delirium. There were significant lower BI scores in patients with dementia and delirium compared with those without up to 180 days after discharge, but no difference was seen in the depression group. In general, patients had delirium or dementia had worsening functional status, even though significant magnitude of improvements on BI scores after discharge. Conclusions Depression does not affect patients’ ADLs. On the other hand, dementia and delirium can persistently limit patients’ physical function. Future care should focus more on dementia and delirium to restore function.
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