Individual characteristics
The participants’ demographic characteristics in mixed methods, the total qualitative method consisted of 25 participants with COVID-19 with 15 of them were severe symptoms while the other 10 were of non-severe symptoms. They were 10 males and 15 females, with an average age of 52 years (range from 21 to 85 years old). Eight of them were admitted to the ICU, 10 to the COVID ward, and 7 of non-hospitalization. The participants of the quantitative group were 180 including 45 of severe cases (25%), and 135 of non-severe cases (75%). They were 56 males (31%), and 124 females (69%), vulnerable people (aged ≥60, co-morbidity, and pregnant women) 87 (48%), non-vulnerable 93 (52%). Additionally, there were non-vaccination 32 (18%), and vaccination 148 (82%).
In this mixed method study, the qualitative and quantitative data were integrated in each major theme. The analysis of data revealed six major themes emerged with ten sub-themes (Figure 1). In addition, a grounded theory framework was built (Figure 2).
Theme 1 Severity of COVID-19 symptoms
Fifteen participants were severe symptoms, all of them expressed that they were long-termed admitted in ICU or COVID-ward for 28-40 days. According to symptoms were progression of infection, they mentioned that, they had dyspnea/ difficult breathing or shortness of breath, tiredness, fever and shiver, headache, backache, sore throat, stomach upset, diarrhea, etc. Three of them were shocked and unconsciousness. They told:
I have high fever and shiver, took medication and warm wipe to reduce fever. It helped me a bit. The nurses helped me by giving me some oxygen but didn’t work well after that I had blackout. I was conscious again, a tube was inserted in my throat and connected to the monitor. There were many tubes on me. A few days later the doctor had to make a hole on the outside of my throat to help me breathing better. I was admitted in ICU for 30 days and was transferred to the primary hospital for 10 more days. (S-female, 47)
The non-severe cases of high-risk group, including the patients of cancer, diabetes mellitus (DM), hypertension, heart disease, chronic kidney disease (CKD), obesity, and pregnant woman, were admitted in order to monitor closely. They took Favipiravir which helped them to recover very soon, by 7-14 days.
I had mild symptoms, having low fever, headache, body aches but I was in a risk group I have cancer and on chemotherapy. The doctor advised me to be admitted. When I walked to the toilet, I felt too tired. I needed to have oxygen and took Favipiravir then I felt better. I stayed in the hospital for 4 days and 14 days for home isolation. (N-S 10 female, 59 y)
Theme 2 Death anxiety
Participants’ increasing of stress, fear of death and anxiety, sadness when their symptom conditions had worsened. They were afraid of dying from lung infection. They expressed fear of facing lonely dying, hopelessness. Two of them were pregnant women, who mentioned that fear of death fetus due to lung problems and shortness of breath. They had experienced the death of other patients in the ICU every day and the bad news of family death, which were situational stressor.
At that moment, I was so worried, feared the death. I was not ready to die I haven’t done anything yet about my assets and will management. (S- male,75y)
For me, I had mild symptoms, took anti-viral drugs for 2-3 days. I felt much better, but my 2-year-old daughter had fever and her test of ATK was positive. Her fever wasn’t that high but she developed seizure. I’m so sorry for her, felt so sad and worried about her. I didn’t want to lose her and I cried a lot, couldn’t sleep, no time to rest. I started to have chest pain, shortness of breath, coughing a lot. I couldn’t stand how I felt at that time. Then I thought that I had to be stronger in order to looking after my daughter. The time has gone by 2 months I’m still scared for her critical. (NS- male, 43y)
Theme 3 Uncertainty
Participants had the uncertainty of severe symptoms and unknown prognosis. The false negative results of COVID test were found and needed to repeat 3-5 times to find a positive result. The most of them did not trust the efficacy of COVID vaccine. They were worried about the side effects of them. They were 4 older adults with underlying diseases and all 2 pregnant women haven’t got any vaccination because there weren’t any recommendations for the testimonial of vaccine. Some of them had lost their family member.
I was not expected to be infected. I had the problem of both ATK and PCR test results. I had done for 4 times, the results were negative until the fifth time, mine was positive. In spite of the onset of the symptoms became apparent and getting worse. (NS- male, 43 y)
I was admitted for oxygen therapy at all time. There was a bad news during my admission. My son who had cirrhosis of liver with COVID infection and died after 5 days admission. I was so sad, I did not expect him to die so soon. That was reality uncertainty. (S-female 75 y)
I protected myself strictly because my work was related to COVID infection patients. I wore N 95 double masks and face shield all time including washing my hands frequently. The first COVID infection was on August 24, 2021. I had got it from my work place and Delta virus was found. On March 5 ,2022, I was infected again with Omicron virus….could not believe it. (NS- male, 29 y)
Theme 4 Barrier to healthcare access
Participants expressed that Delta variant was so dangerous and spread easily. The risk group or vulnerable group acknowledged the danger of it. There are aging people, pregnant women. The underlying disease such as DM, hypertension, cancer, chronic lung disease, chronic kidney disease (CKD), etc. At that moment, the situation area was critical and in peak conditions. The people were panic when they focused on the number of infected and dead people, fought for rapid antigen test and for admission as well. Participants mentioned that the official announced that there were many sick and dead people, so the hospitals in Bangkok would not be able to handle them.
I was certain of Delta virus was so dangerous, even though I protected myself really good but I still got it. (NS male, 43 y)
In 2021, while I was infected, the situation was so scared. There were many infected people sending by the ambulances to the hospitals but there were not enough health services even COVID screening.
(S-male,75y)
I contacted many hospitals in Bangkok, there was not the place for COVID test or the admission waiting was for 3 days, I felt worse, so my husband with my kid took me in our car in up country, far away more than 400 kilometers. Luckily I was admitted in a hospital, if not I would die.
(S- female 47y)
Theme 5 Compliance and self-regulation coping
The participants expressed their experiences of the onset coping. They would have done the COVID test, using ATK by themselves, and went to hospitals for their treatment. They would follow all the rules and accepted to do so because they were afraid of dying, thinking positively that everything would be better. The severe group, they complied everything as the health care provider advised, and patience to suffering in the ICU. For non-severe group, they would do as advised by well-informed persons, using alternative therapy such as consuming herbs, in order to decrease cough, and sore throat. They were remote treated by Favipiravir sending from the hospital. Some cases used spiritual and religion dimensions. Moreover, social supports, such as helping of family, and health volunteers made them secured.
I prayed with a little Buddha image which I brought with me to the ICU that made me mindful, distractions, lay on lateral side and on oxygen therapy all the time as the nurse advised. And I felt better. (S-pregnant woman, 31 y)
The nurses advised me to lay on the stomach and I must do as they advised. I could do only 5-7 minutes in the daytime, but the night time I was so afraid that no one could come to help me in case the oxygen tube was missing. (S-female, 75 y)
My daughter who looked after me, call the ambulance taking me to the hospital. She had talked to the doctor via phone every day and let me know all that. (S-male,75 y)
Theme 6 Post COVID-19 effects
Almost all participants remained post COVID-19 symptoms such as tiredness, headache, fatigue and decreased activity tolerance. A few cases, the sugar level was increasing, the doctor prescribed the medication to control it. Increasing of allergies, the lungs had fibrosis, and hands and feet were numb. The memory was decreased. In case of pregnant woman, expressed that the baby was been both of valve stenosis and regurgitation.
I was discharged 6 months ago. At the moment I am not the same, easily tired. My sugars level was increased, the doctor prescribed me more medication for my DM. (S-female, 47 y)
After my baby was born by surgery his weight was 3,000 grams and being easy baby. The doctor told me that he had abnormal heart valves. There were both of leakage on the right side and stenosis on the tip of lung.
I believed it was caused by COVID infection, but the doctor stated that
the baby might have it as a congenital disease. (S-pregnant female, 29 y)
In this mixed methods study, the qualitative and quantitative data were integrated in each major theme using a new instrument. This phase was examined physical distress, psychological distress and coping experiences among people with infected COVID-16. The findings revealed that overall physical distress was at a moderate level (mean =48.06, SD= 19.93), psychological distress was at a moderate level (mean= 52.01, SD =20.94). The coping was at a moderate level (mean =37.68, SD= 13.92) respectively.
The relationship between physical distress, psychological distress, and coping among people with infected COVID-19. There were as follows (Table 1).
Table 1 Correlation of physical distress, psychological distress, and coping among people with infected COVID-19 (n=180)
No.
|
Variables
|
1
|
2
|
3
|
p-value
|
Mean
|
SD
|
1
|
Physical distress
|
-
|
.62**
|
.18*
|
<.001,<.05
|
48.06
|
19.93
|
2
|
Psychological distress
|
-
|
-
|
.33**
|
<.001
|
52.01
|
20.94
|
3
|
Coping
|
-
|
-
|
-
|
-
|
37.68
|
13.92
|
The comparison of physical distress, psychological distress, and coping between the non-severe group and severe group was employed independent t-test. The matching of the participants’ age in the non-severe group and severe group were administered. There were 45 for each equally, a total of 90 (Table 2).
Table 2 Comparisons of mean difference of physical distress, psychological distress, and coping
between non-severe and severe group by using independent t-test
Variables
|
Non -severe group
n=45
|
Severe group
n=45
|
t-test
|
p-value
|
mean
|
SD
|
mean
|
SD
|
Physical distress
|
48.06
|
13.98
|
71.02
|
7.16
|
-14.66
|
< .001
|
Psychological distress
|
38.71
|
16.31
|
66.15
|
19.09
|
-7.33
|
< .001
|
Coping
|
34.46
|
13.17
|
40.68
|
12.88
|
-2.26
|
< .05
|
Note: ES= -.47 (Cohen’s d), large effect size
The Post-COVID-19 effects during the 1st and 6th months were 70% effects (Table 3).
Table 3. Post COVID-19 effects (n=180)
Effect of COVID-19
|
frequency
|
percent
|
Non-effects
|
54
|
30
|
Effects
|
126
|
70
|
1. Decreased activity tolerance
|
72
|
40
|
2. Fatigue
|
60
|
33
|
3. Anxiety / fear of abnormal lungs
|
60
|
33
|
4. Dyspnea
|
50
|
27
|
5. Allergy and asthma
|
44
|
24
|
6. Lung impairment
|
40
|
22
|
7. Cough/ sore throat
|
23
|
13
|
8. Muscle pain / back pain /and neck pain
|
23
|
13
|
9. Drowsiness
|
23
|
13
|
10. Sleep disturbance
|
22
|
12
|
11. Loss of appetite
|
22
|
12
|
12.Headache
|
13
|
7
|
13.Hypertension (HT)
|
12
|
6
|
14. High blood sugar level
|
12
|
6
|
15. Memory impairment
|
10
|
5
|
16. Palpitation / chest pain
|
8
|
4
|
17. Hair loss/ fragile nail
|
6
|
3
|
18. Hyper platelet and stroke
|
3
|
2
|
19. Eyes impairment
|
2
|
1
|
20.The others: liver, kidney impairment,
gout, and neuritis
|
12
|
7
|
Note: Many of them had more than 3 effects