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Research article
Sajad Keshavarz
Islamic Azad university
Corresponding Author
ORCiD: https://orcid.org/0000-0003-1103-6810
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
The effect of extremely low frequency electric field on cancer cell proliferation is studied in-vitro.
Methods
Prostate cancer cell culture type Du-145 has been grown in the form of spheroids. It is shown that ELF with 50Hz frequency is effectively suppressing the growth of spheroids and finally reduces their size.
Results
It is observed that low voltage low frequency electric filed applied for at least 2 hours a day over one week can stop the growth or even reduce the volume of multi-cellular tumor spheroids significantly. No effect for the case of electric field presence in order of 10 -30 minutes per day has been observed.
Keywords
Prostate cancer, 50Hz electric field, cell line, Du-145
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research article
Sajad Keshavarz
Islamic Azad university
Corresponding Author
ORCiD: https://orcid.org/0000-0003-1103-6810
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 28 Aug, 2019
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
The effect of extremely low frequency electric field on cancer cell proliferation is studied in-vitro.
Methods
Prostate cancer cell culture type Du-145 has been grown in the form of spheroids. It is shown that ELF with 50Hz frequency is effectively suppressing the growth of spheroids and finally reduces their size.
Results
It is observed that low voltage low frequency electric filed applied for at least 2 hours a day over one week can stop the growth or even reduce the volume of multi-cellular tumor spheroids significantly. No effect for the case of electric field presence in order of 10 -30 minutes per day has been observed.
Figure 1
Figure 2
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