Rational construction of Co-promoted 1T-MoS2 nanoflowers towards high-efficiency 4-nitrophenol reduction

Developing efficient and cost-effective non-noble metal catalysts for the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) is of great importance. Herein, Co-promoted 1T-MoS2 nanoflowers were synthesized via a one-step hydrothermal method. The influence of Co content on the structure and catalytic performance of 1T-MoS2 was studied in detail. It was found that Co doping not only enhanced the electronic conductivity but also increased the hydrogen adsorption ability of 1T-MoS2. Meanwhile, the highest activity was achieved due to the synergy effect of Co-Mo-S and CoS2 active phase. In the catalytic reduction of 4-NP, the reaction rate constant of Co/1T-MoS2-0.3 was as high as 0.908 min−1 and the catalyst exhibited excellent stability after recycling five times. The present work provides new insights for the rational design of highly efficient metal-doped MoS2 catalysts towards 4-NP reduction in wastewater.


Introduction
Over the past few decades, water pollution has been a concerned environmental problem due to the rapid development of modern industry. Aromatic nitro compounds especially 4-nitrophenol (4-NP) is considered as one of the most difficult pollutants to be removed in the polluted water due to its high stability and toxicity (Jiang et al. 2021;Liu et al. 2021a;Yadav et al. 2020;Zhang et al. 2021b). However, as the reduction product of 4-NP, 4-aminophenol (4-AP) has been widely used in medicine and dye industry (Ramalingam et al. 2020;Rossi et al. 2021;Tayyab et al. 2022). Several reduction technologies such as catalytic reduction (Li et al. 2022, Sinha andPurkayastha 2022) or photocatalytic reduction (Ferreira et al. 2021;Li et al. 2019;Lu et al. 2021) have been developed to solve 4-NP pollution in wastewater. Among these technologies mentioned above, catalytic reduction utilizing NaBH 4 as reducing agent has the advantages of being low cost and environmentally friendly.
According to previous report, the selective reduction of 4-NP is a thermodynamically feasible technology. However, high energy barrier and slow kinetics prevent the chemical reaction from taking place efficiently (Danish et al. 2021;Liu et al. 2021b;Su et al. 2013). Hence, it is of great importance to develop highly active catalysts to accelerate this selective reduction reaction. So far, some noble metals such as Au Nasaruddin et al. 2022), Ag (Doan et al. 2021;Paul et al. 2021), Pt (Yang et al. 2022b), and Pd (Gholinejad et al. 2022, Liu and Bai 2021, Wang et al. 2022, Zhang et al. 2020a) have been reported to show good catalytic activity for 4-NP reduction. However, high price and scarcity limit the large-scale industrial application of precious metals. Alternatively, two dimensional molybdenum disulfide (MoS 2 ) was recently found as a promising non-noble metal material for catalyzing the 4-NP reduction reaction Lin et al. 2015;Nethravathi et al. 2017;Ni et al. 2021;Peng et al. 2016;Qiao et al. 2017;Yang et al. 2022a;Zhang et al. 2020b). However, the catalytic Responsible Editor: George Z. Kyzas active sites of MoS 2 are mainly located at the coordinatively unsaturated edge planes instead of basal planes according to both the experimental and theoretical results, which limits the catalytic performance of MoS 2 . Therefore, a series of strategies have been developed to improve the catalytic performance of MoS 2 such as phase engineering, composite modification, defect engineering, and elemental doping. For example, Guardia et al. reported that exfoliated MoS 2 nanosheets with dominant 1T phase are efficient 4-NP reduction catalysts (Guardia et al. 2014). Meng et al. developed a highly efficient 1T-MoS 2 /RGO nanocomposite catalyst by combining the advantages of both exfoliated 1T-MoS 2 nanosheets and reduced graphene oxide (RGO) (Meng et al. 2017). Lin et al. prepared a Fe 3 O 4 @MoS 2 core-shell catalyst with oxygen incorporation and defect-rich structure in MoS 2 nanosheets, which showed excellent performance in the reduction of 4-NP (Lin et al. 2015). Peng et al. demonstrated that MoS 2 /pillared-montmorillonite hybrids with enlarged interlayer spacing showed enhanced catalytic activity (Peng et al. 2016). Besides, the catalytic performance of 2H-MoS 2 could also be improved by transition metal doping. Consequently, the promoters (Ni or Co) can donate electrons to Mo, thus weakening the strength of Mo-S bond and facilitating the desorption of hydrogen (Ni et al. 2021). As far as we know, most of the previous researches only adopted one approach to enhance the catalytic performance of MoS 2 , and few studies have combined two or more advantages above. In our previous work, we reported a one-pot hydrothermal synthesis of ultrathin 1T-MoS 2 nanosheets with oxygen doping and rich defects, which exhibited excellent catalytic activity in the reduction of 4-NP to 4-AP . Therefore, the catalytic activity of 1T-MoS 2 in the reduction of 4-NP can be further boosted by regulating the electronic structure and the ability to activate hydrogen of 1T-MoS 2 through Co doping.
Herein, in present work, Co promoters were incorporated into 1T-MoS 2 by a facile one-step hydrothermal method. The synergy effect between Co promoters and 1T-MoS 2 was characterized in detail, and the catalytic performance of Co-doped 1T-MoS 2 catalysts was evaluated in the reduction of 4-NP. Finally, the structure-performance relationship was revealed to shed light on the rational design of highly efficient MoS 2 -based materials for 4-NP catalytic reduction.

Catalyst preparation
The Co-promoted 1T-MoS 2 nanoflowers were prepared by a one-pot hydrothermal method. Typically, 4/7 mmol (NH 4 ) 6 Mo 7 O 24 ·4H 2 O and 24 mmol CS(NH 2 ) 2 and Co(NO 3 ) 2 ·6H 2 O were dissolved in 20 mL deionized water and stirred for 15 min to form a clear solution. Then, the mixed solution was transferred to a 50-mL Teflon-lined autoclave and hydrothermally treated at 180 °C for 24 h. The obtained black products were washed for several times and dried under vacuum at 60 °C. Finally, the as-prepared catalysts were denoted as Co/1T-MoS 2 -X, where X represents the Co/Mo molar ratio in the initial solution (X = 0.05, 0.1, 0.3, and 0.5).

Catalyst characterization
Powder X-ray diffraction (XRD) patterns were recorded on a PANalytical X'Pert PRO MPD diffractometer. The textual properties were measured on a Micromeritics ASAP2460 instrument by physisorption of N 2 at 77 K. The morphology of catalysts was observed on a Zeiss Sigma 300 emission scanning electronic microscopy (SEM). High-resolution transmission electron microscopy (HRTEM) tests were carried out on a FEI Tecnai F20 electron microscope. X-ray photoelectron spectroscopy (XPS) tests were conducted on a Thermo Scientific K-Alpha spectrometer equipped with Al Kα excitation source (hν = 1486.6 eV). H 2 -temperature programmed desorption (H 2 -TPD) was performed on a home-made instrument with a thermal conductivity detector (TCD). Prior to the test, the catalysts were pretreated in Ar flow at 120 °C for 30 min. After cooling to 50 °C, the samples were adsorbed with 10% H 2 /Ar (60 mL min −1 ) for 30 min. Then, the temperature was increased to 500 °C with the heating rate of 10 °C/min under Ar flow. The electrochemical impedance spectroscopy (EIS) measurements were carried out on a CHI 760E electrochemistry workstation (Shanghai Chenhua) based on a standard three-electrode system in 0.5 M PBS buffer solution (Na 2 HPO 4 /NaH 2 PO 4 ). The work electrode was prepared as follows: 5 mg catalysts were ultrasonically dispersed in a mixture solution containing 500 µL of ethanol and 20 µL of 5 wt% Nafion. Then, 10 µL of the ink was loaded onto a glassy carbon electrode with diameter of 3 mm. The graphite rod and Ag/AgCl were used as counter and reference electrodes, respectively. The EIS tests were performed from 0.1 Hz to 100 kHz with AC amplitude of 5 mV.

Catalytic performance evaluation
The catalytic performance of Co-promoted 1T-MoS 2 catalysts was evaluated in the reduction of 4-nitrophenol. Typically, 200 μL of 4-nitrophenol aqueous solution (1 mM) and 2.5 mL fresh NaBH 4 solution (10 mM) were added to a quartz cuvette with optical path of 1 cm. Then, 100 μL catalysts (2.5 mg/mL) were added to trigger the reaction. The UV-vis spectra were recorded on a UV-vis spectrophotometer (Shimadzu UV-2450) for every 1 min to monitor the reaction progress. For the stability test, the catalysts were collected by centrifuging the suspension after reaction and used for next run.

Catalytic performance in the reduction of 4-NP
The catalytic performance of 1T-MoS 2 and Co-promoted 1T-MoS 2 catalysts was evaluated in the catalytic reduction of 4-NP as a model reaction. Although the reaction is thermodynamically feasible, it does not take place without a catalyst as shown in Fig. 1a. Once a proper catalyst is added, the reduction reaction will be immediately initiated. Typically, the absorption peak of 4-NP at 400 nm (yellow color) gradually weakened, and finally, a new absorption peak of reduction product 4-AP (clear solution) appeared at 300 nm (Fig. 1b). Therefore, the time-dependent reaction could be monitored in situ by UV-vis spectroscopy. Combined with Fig. 1c, d, it can be seen that the reaction was nearly completed within 5 min under the catalysis of Co/1T-MoS 2 -0.3 while there are still some 4-NP left when 1T-MoS 2 was used, demonstrating the excellent catalytic activity of Co/1T-MoS 2 -0.3. The detailed conversion vs reaction time curves of 1T-MoS 2 and Co/1T-MoS 2 -X catalysts are displayed in Fig. 1e. Obviously, the catalytic performance of 1T-MoS 2 was improved when promoted with Co. With the gradual increase of Co content, the catalytic activity firstly reached the highest value at Co/1T-MoS 2 -0.3 and then decreased. To further distinguish the difference in catalytic activity, the apparent reaction rate constants were calculated. In this reaction, the concentration of NaBH 4 was almost unchanged during the reaction process by considering 4-NP/NaBH 4 molar ratio of 1:125. Hence, the quasi-first-order kinetics is appropriate when applied in the reduction of 4-NP (Ahamad et al. 2020; Ling et al. 2020). The good linear relationship between ln(C t /C 0 ) and reaction time (t) of all catalysts further confirms the assumption of quasi-first-order feature (Fig. 1f). The calculated rate constants of 1T-MoS 2 , Co/1T-MoS 2 -0.05, Co/1T-MoS 2 -0.1, Co/1T-MoS 2 -0.3, and Co/1T-MoS 2 -0.5 were 0.528, 0.619, 0.704, 0.908, and 0.592 min −1 , respectively. Besides, the supplementary performance results of Co/1T-MoS 2 -0.2 and Co/1T-MoS 2 -0.4 also demonstrated that Co/1T-MoS 2 -0.3 had the highest catalytic activity ( Fig. S1 and Table S1). The above results show that an appropriate amount of Co doping could maximize the catalytic performance of 1T-MoS 2 . In order to understand the influence of Co doping on the structure and catalytic activity of 1T-MoS 2 , the catalysts were characterized in detail.

Catalyst characterization results
To determine the crystallographic structure and phase purity of 1T-MoS 2 and Co-promoted 1T-MoS 2 catalysts, XRD characterization was carried out and the results are shown in Fig. 2. The diffraction peaks at 2θ = 9.3°, 18.6°, 32.3°, 35.4°, and 57.4° are indexed to the (002), (004), (100), (103), and (110) crystal planes of 1T-MoS 2 (Liu et al. 2015). Compared with 2H-MoS 2 , the diffraction peak of (002) plane shifts from 14° to a lower angle of 9.3°, indicating the expanded interlayer spacing of 1T-MoS 2 . The average layer number of 1T-MoS 2 calculated by Debye-Scherrer equation using the full width at half maximum intensity (FWHM) of (002) peak is about 3.3, demonstrating a few-layer structure. After incorporating a very small amount of Co, the diffraction peak of 1T-MoS 2 is almost unchanged for Co/1T-MoS 2 -0.05 which indicates that the Co atoms are well embedded in the skeleton of 1T-MoS 2 . By further increasing the Co/Mo molar ratio to 0.1, the characteristic patterns of 1T-MoS 2 are obviously weakened but still no separated Co x S y particles are observed for Co/1T-MoS 2 -0.1. With the gradual increase of Co content, another group of diffraction peaks at 2θ = 28.2°, 32.5°, 36.4°, 40.2°, 46.5°, 55.4°, 60.4°, and 63.0° corresponding to small CoS 2 crystallites (JCPDS Card No. 41-1471) starts to appear on the Co/1T-MoS 2 -0.3, and the CoS 2 particles grow larger if excess Co content was incorporated.
The textual properties of 1T-MoS 2 and Co-promoted 1T-MoS 2 catalysts were characterized by nitrogen physisorption. As shown in Fig. 3a, all the catalysts display typical type IV isotherms which indicates that the materials are stacked by sheet particles (Leofanti et al. 1998). The pore size distribution in Fig. 3b shows that the pore channels of all catalysts are in the mesoporous range. Besides, 1T-MoS 2 and Co/1T-MoS 2 -0.05 have bimodal pore distribution while the large pores disappear if more Co were incorporated. The surface area and total pore volume listed in Table 1 decrease in the following order: 1T-MoS 2 (49.9 m 2 /g, 0.211 cm 3 /g) > Co/1T-MoS 2 -0.05 (35.6 m 2 /g, 0.163 cm 3 /g) > Co/1T-MoS 2 -0.1 (27.2 m 2 /g, 0.096 cm 3 /g) > Co/1T-MoS 2 -0.3 (15.7 m 2 /g, 0.062 cm 3 /g) > Co/1T-MoS 2 -0.5 (8.5 m 2 /g, 0.041 cm 3 /g). The reduction of surface area and total pore volume are mainly caused by pore filling of Co species. In addition, larger CoS 2 particles formed by excessive Co The morphology of 1T-MoS 2 and Co-promoted 1T-MoS 2 catalysts was observed by scanning electronic microscopy (SEM). As shown in Fig. 4a, 1T-MoS 2 displays a typical flower morphology with diameter of 0.5-1.5 μm. In order to reduce the total surface energy, a large number of MoS 2 nanosheets are assembled spontaneously to form a flower-like structure. After promoted with a small amount of Co additives, the flake morphology and flower structure of MoS 2 aggregates are well maintained for Co/1T-MoS 2 -0.05 and Co/1T-MoS 2 -0.1 (Fig. 4b, c). However, when the Co/Mo molar ratio increases to 0.3, some cubic-shaped nanoparticles attributed to CoS 2 are found to deposit on the surface of 1T-MoS 2 nanoflowers (Fig. 4d). Besides, the energy-dispersive X-ray (EDX) mapping results (Fig. S2) show that Co, Mo, S, O, and N elements are evenly distributed in the whole region of Co/1T-MoS 2 -0.3. The presence of N elements confirms the successful intercalation of NH 3 molecules which induced phase transition from 2H-MoS 2 to 1T-MoS 2 . If too much Co was added, the flake morphology of MoS 2 flower is gradually weakened and larger CoS 2 aggregates are formed for Co/1T-MoS 2 -0.5 (Fig. 4f). This observation illustrates that Co atoms preferentially enter the structure of 1T-MoS 2 when incorporated. However, if there are not enough sites in the crystal structure of MoS 2 to accommodate Co, the Co species will gather and form separated CoS 2 particles. The as-formed CoS 2 aggregates thus inserted between MoS 2 nanosheets blocked the large pores, in consistent with the XRD and N 2 -physisorption results.
To further explore the effect of Co doping on the microstructure of 1T-MoS 2 , the HRTEM images of 1T-MoS 2 and Co/1T-MoS 2 -0.3 are provided in Fig. 5. The black fringes with interlayer spacing of 0.93 nm in Fig. 5a are assigned to the (002) planes of 1T-MoS 2 . The enlarged d-spacing compared with 2H-MoS 2 (0.65 nm) is resulted from NH 3 intercalation according to our previous report . The zoom-in image of (002) basal plane clearly shows a trigonal atomic arrangement which is typical characteristic of 1T phase . Besides, the statistical analysis by counting 200 particles demonstrates the average layer number (N av ) and average slab length (L av ) of 1 T-MoS 2 of 3.1 and 22.8 nm, respectively (Fig. S3). Another different group fringes with spacing of 0.25 nm are observed on Co/1T-MoS 2 -0.3 which corresponds well to the (210) planes of cubic CoS 2 pyramids (Fig. 5b). From the SEM and HRTEM results, it is concluded that the CoS 2 particles are deposited on the surface of 1T-MoS 2 nanosheets, and these two phase are in close contact.
The surface species and chemical valence states of 1T-MoS 2 and Co/1T-MoS 2 -0.3 catalysts were characterized by X-ray photoelectron spectroscopy (XPS). As shown  Fig. 6a, 1T-MoS 2 has two dominant peaks located at 228.3 and 231.4 eV which are attributed to Mo 4+ 3d 5/2 and Mo 4+ 3d 3/2 of 1T phase, which agrees well with previously reported 1T-MoS 2 materials (Cao et al. 2021b;Liu et al. 2017). Besides, two other oxidation state Mo species are also found which are assigned to MoS x O y (229.0 eV 3d 5/2 , 232.1 eV 3d 3/2 ) and Mo 6+ (232.3 eV 3d 5/2 , 235.4 eV 3d 3/2 ). As for the S 2p spectra, the doublet at 161.3 and 162.4 eV is assigned to S2p 3/2 and S2p 1/2 orbitals of S 2− species (Fig. 6b). The existence of MoS x O y and Mo 6+ species indicates an incomplete sulfidation of Mo species caused by the low hydrothermal synthesis temperature. It is widely accepted that only the Mo 4+ species could act as active centers, and the sulfidation degree is defined as the proportion of Mo 4+ to the sum of all Mo species . For the Co/1T-MoS 2 -0.3 catalyst, the binding energy of all Mo species and S 2− species is positively shifted by about 0.2 eV which suggests a strong electronic  interaction between Co and 1T-MoS 2 . In addition, it was found that the proportion of Mo 4+ increased and the content of MoS x O y and Mo 6+ species decreased after incorporating Co, indicating that Co promotion could effectively improve the sulfidation degree of Mo species. To further identify the chemical state of Co species, the Co 2p 3/2 spectra of Co/1T-MoS 2 -0.3 was deconvoluted. As shown in Fig. 6c, three different species are observed which could be attributed to Co-Mo-S (778.6 eV), CoS 2 (779.0 eV), and Co oxides (782.2 eV) . As a comparison, the Co-Mo-S phase is not shown in XRD pattern because it might exist as a very small crystallite.
According to the above characterization results, the effect of Co incorporation on the structure of 1T-MoS 2 is summarized in Scheme 1. When Co is added to 1T-MoS 2 , the Co atoms are firstly anchored on the edge planes of 1T-MoS 2 to form Co-Mo-S active phase (Lauritsen et al. 2001). In this case, there would be electron transfer between Co, Mo, and S atoms, which promotes the sulfurization degree of Mo species to form more Mo(IV) active species. With the increase of Co content, the anchor sites on the edge planes of 1T-MoS 2 are gradually covered completely, thus forming isolated CoS 2 phase. If too much Co is added, a large number of CoS 2 particles

Proposed reaction mechanism
According to the results above in present work and some reported literatures, a plausible reaction mechanism is suggested for the reduction of 4-NP by using Co-promoted 1T-MoS 2 catalysts (Scheme 2). The whole reaction process can be divided into four typical steps based on Langmuir-Hinshelwood model (Wunder et al. 2011;Zhou et al. 2018): (I) electrons are transferred from BH 4 − to the catalyst surface and the adsorbed hydrogen species are formed; (II) electrons jump freely on the catalyst surface to form an electron-rich region; (III) adsorbed hydrogen species and surface electrons simultaneously attack the adsorbed 4-NP molecules, resulting in the breakage of N-O bonds and the formation of reduced product 4-AP; and (IV) 4-AP is desorbed from the catalyst surface, and the initial state of active sites is recovered for next catalytic cycle.
Scheme 1 Illustration of structure evolution of Co-promoted 1T-MoS 2 with the increase of Co content Scheme 2 Proposed catalytic mechanism in the reduction of 4-NP utilizing Co/1T-MoS 2 -0.3 as catalyst Although Co incorporation results in the decrease of specific surface area, it is clear that there is no direct correlation between catalytic activity and surface area ( Fig. 1 and Table 1). Thus, conductivity and hydrogen adsorption capability are two important factors affecting the catalytic performance in the reduction of 4-NP. As shown in Fig. 7, the electrical resistance characterized by electrochemical impedance spectroscopy (EIS) showed a decrease in the order: 1T-MoS 2 > Co/1T-MoS 2 -0.5 > Co/1T-MoS 2 -0.1 > Co/1T-MoS 2 -0.3, indicating that the electron transfer kinetics of 1T-MoS 2 was enhanced after Co promotion and Co/1T-MoS 2 -0.3 had the best electron transfer efficiency. The H 2 -TPD curves in Fig. 8 displayed that 1T-MoS 2 had a H 2 desorption peak at around 250 °C while Co/1T-MoS 2 -0.1 showed a doublet at 250 °C and 294 °C. Besides, Co/1T-MoS 2 -0.3 exhibited a broad peak centered at 294 °C, and Co/1T-MoS 2 -0.5 showed a rather weak peak around 315 °C. Usually, a higher desorption temperature and bigger peak area represented a higher H 2 adsorption capability. Hence, the adsorption ability of H is enhanced by the formation of Co-Mo-S active phase , thus resulting in a higher enrichment degree of H species on the catalyst surface. Additionally, a suitable amount of oxygen incorporation confirmed by the EDX mapping and XPS results is beneficial for improving the electrical conductivity and facilitating the charge transfer process (Saadati et al. 2021). As a consequence, the reaction rate of step III is improved and the whole catalytic activity is enhanced. Meanwhile, CoS 2 particles could also activate BH 4 − and the spillover hydrogen species then migrate to the surface of 1T-MoS 2 which was well explained by remote control model (Ojeda et al. 2003;Wang et al. 2016). Therefore, the concentration of surface H active species is further increased due to the synergistic effect between Co-Mo-S and CoS 2 phase, resulting in the highest catalytic activity of Co/1T-MoS 2 -0.3. However, the catalytic activity of Co/1T-MoS 2 -0.5 is decreased because a large amount of Co-Mo-S active sites are covered. Hence, only an appropriate amount of Co promotion could maximize the synergism between Co and 1T-MoS 2 , which significantly boosts the reduction activity of 4-NP.

Stability test of Co/1T-MoS 2 -0.3 and comparison with other reported MoS 2 -based catalysts
The catalytic stability was tested by recycling the Co/1T-MoS 2 -0.3 for several times. In order to facilitate the recovery of catalyst for stability testing, the reaction volume was increased by 10 times. As shown in Fig. 9a, the 4-NP conversion was decreased from 99.2 to 96.3% after testing for 5 times. The reduced catalytic activity might be caused by the weight loss of catalyst during recovery process. XRD patterns of fresh and spent catalysts display that the structure of 1T-MoS 2 and CoS 2 is maintained after recycling test, suggesting the good stability of Co/1T-MoS 2 -0.3 (Fig. 9b). However, the peak intensity of CoS 2 showed a modest decrease after test, which might be caused by in situ interaction between 1T-MoS 2 and CoS 2 during the reaction. Catalytic performance comparison of Co/1T-MoS 2 -0.3 in the present work and other reported MoS 2 -based catalysts is summarized in Table 2. It could be seen that the 4-NP reduction activity of Co/1T-MoS 2 nanoflowers is better than most of the reported MoS 2 -based catalysts.

Conclusions
Co doping can not only affect the electronic structure of 1T-MoS 2 but also facilitate the activation of hydrogen. When incorporating Co into 1T-MoS 2 , Co was preferentially anchored at the edge sites to form Co-Mo-S active phase which promoted the electron transfer kinetics and the hydrogen adsorption ability, thus improving the catalytic activity for 4-NP reduction. By further increasing the Co content, isolated CoS 2 particles were deposited on the surface of 1T-MoS 2 nanoflowers, which could provide spillover hydrogen to further enhance catalytic performance. With an appropriate Co/Mo molar ratio, Co/1T-MoS 2 -0.3 showed the highest catalytic activity of 0.908 min −1 and excellent recycling stability of five times due to the optimal synergism between Co-Mo-S and CoS 2 . This work provides a promising candidate for removing the organic nitro-compounds in wastewater. In the future work, the influence of other transition metals (Fe, Ni, Cu, or Zn) doping on the catalytic performance of 4-NP reduction will be investigated.
Author contribution All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by Cen Zhang, Li Wang, Xi Huang, Liang Bai, Qiyuan Yu, Bin Jiang, and Chenlu Zheng. The first draft of the manuscript was written by Jing Cao, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. Data availability All data during this study are included in this article.

Declarations
Ethics approval Not applicable.

Conflict of interest
The authors declare no competing interests.