The wireless networks of upcoming fifth generation (5G) promises connection speeds and data rates that are one hundred times faster than the existing networks and much improved signal and connection quality. As there is the development of wireless communication systems, the requirement of Power Amplifier’s linearity is hard. The Radio Frequency (RF) power amplifiers that are operating with wideband signals such as WCDMA that is used in UMTS leads to the generation of out-of-band emissions which are referred as “Spectral regrowth”. To improve PA efficiency and linearity, this paper uses Digital Predistortion technique. This paper of DPD in combination with power amplifier using Memory Polynomial Algorithm is designed in the MATLAB/SIMULINK. The designed algorithm was tested with against various test cases and it was observed with high non-linearity and the good performance is seen for the order of 4 and 5 of the memory polynomial and non-linearity coefficients having linear output. Hence by using Memory Polynomial DPD in this paper the output of the previous input and present input is obtained. The advantage of DPD is having a linear power amplifier with less distortion and high non-linearity.